Sialic Acid Receptor Specificity in Mammary Gland of Dairy Cattle Infected with Highly Pathogenic Avian Influenza A(H5N1) VirusResearch Published on 2024-07-012024-09-05 Journal: Emerging Infectious Diseases [Category] update2024, [키워드] dairy cattle epithelial cell H5N1 highly pathogenic avian influenza Influenza Macrophage mammary gland Neu5Ac respiratory tract sialic acid United States viruses zoonoses α2,3-gal α2,6-gal [DOI] 10.3201/eid3007.240689 PMC 바로가기 [Article Type] Research
SARS-CoV-2 Spike Protein Stimulates Macropinocytosis in Murine and Human Macrophages via PKC-NADPH Oxidase SignalingArticle Published on 2024-01-302024-09-05 Journal: The Cochrane database of systematic reviews [Category] update2024, [키워드] epithelial cell Macrophage macropinocytosis SARS-CoV-2 [DOI] 10.3390/antiox13020175 PMC 바로가기 [Article Type] Article
EGR1 regulates oral epithelial cell responses to Candida albicans via the EGFR- ERK1/2 pathwayArticle Published on 2023-04-032024-09-05 Journal: bioRxiv [Category] update2024, [키워드] Candida EGR1 epithelial cell [DOI] 10.1101/2023.03.31.535186 PMC 바로가기 [Article Type] Article
Nasopharyngeal epithelial cells from patients with coronavirus disease 2019 express abnormal levels of Toll-like receptorsResearch Article Published on 2023-01-182024-09-05 Journal: Pathogens and global health [Category] update2024, [키워드] Coronavirus disease 2019 epithelial cell Inflammation severe acute respiratory syndrome coronavirus 2 Toll-like receptor [DOI] 10.1080/20477724.2023.2166378 PMC 바로가기 [Article Type] Research Article
Induction of pulmonary HLA-G expression by SARS-CoV-2 infectionArticle Published on 2022-11-052022-11-15 Journal: Cellular and Molecular Life Sciences [Category] SARS, 치료기술, 치료제, [키워드] accompanied Antigen Autopsy biopsies CD8 Cell changes in correlated distribution epithelial cell Evidence expressed expression expression level Frequency heart muscle HLA-G Hyperactivation Immune cell Immune cell infiltration immune cells Immune escape immune response induction information kidney leukocyte lung lung alveolar lung epithelia lung epithelial cell lung tissue Macrophage marker microRNA miRNA miRNA expression modulating organs other organ patients protein expression SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 nucleocapsid SARS-CoV-2- SARS-CoV-2-infected patient specimen Spike protein surgical T cell responses T cells therapeutic target tissue tissues Treatment Tumor virus-infected cells while [DOI] 10.1007/s00018-022-04592-9 PMC 바로가기
Brief Research Report: Serum clara cell 16 kDa protein levels are increased in patients hospitalized for severe SARS-CoV-2 or sepsis infectionArticle Published on 2022-10-132022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 바이오마커, [키워드] age Anti-inflammatory Biomarker case-control study CC16 Cell cell damage chronic pulmonary diseases Concentration disease Diseases ELISA epithelial epithelial cell epithelial cell damage Evidence expressed healthy Increased Infection Infectious disease kDa Lungs Non-pulmonary patients hospitalized patients treated Platelet positively correlated previous study Protein protein level SARS-CoV-2 Sepsis Serum level severe infections severe SARS-CoV-2 significantly increased subjects were measured [DOI] 10.3389/fimmu.2022.1037115 PMC 바로가기
A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugsResearch article Published on 2022-10-012022-10-05 Journal: Journal of controlled release : official journal o [Category] 신약개발, [키워드] addition approach approval bovine CAD cancer cell cationic Cationic amphiphilic drugs Cationic lipid Cell Cellular delivery component Corneal COVID-19 mRNA vaccines drug drug combination Drug repurposing Efficiency encapsulation epithelial cell epithelial cells eyes functional healthcare HeLa cell in vitro in vivo Lipid lipid component Lipid nanoparticles Liposome LNP maintain Messenger RNA mRNA nanomedicine Patient pharmacological platform primary cell RNA RNA therapeutics selected small molecule drug subsequent Therapies Vesicle was obtained [DOI] 10.1016/j.jconrel.2022.08.009 [Article Type] Research article
SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expressionArticle Published on 2022-09-232022-11-16 Journal: Science Advances [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome blood vessels CLDN5 coronavirus coronavirus disease COVID-19 disrupt disrupting down-regulation endothelial epithelial cell expression fluvastatin infect initial investigated junctions lung mechanism organ other organ overexpression patient with COVID-19 produced Protein protein expression rescued respiratory epithelial cell SARS-CoV-2 therapeutic strategy transfer Treatment Vascular [DOI] 10.1126/sciadv.abo6783 PMC 바로가기
Contribution of Trp63CreERT2-labeled cells to alveolar regeneration is independent of tuft cellsArticle Published on 2022-09-212022-11-15 Journal: eLife [Category] 바이오마커, 유전자 메커니즘, [키워드] alveolar alveolar epithelial cell alveolar epithelium alveolar regeneration Basal cell basal cells Biomarkers cause Cell Cell Biology Complete COVID-19 ectopic epithelial epithelial cell function IMPROVE increase independent Infection lineages lung lung parenchyma lung regeneration Lungs mechanism mice mouse mouse model Notch other organs proliferate promote promoted regenerative regenerative medicine regulate significantly stem cells suggested suppressed Tamoxifen tuft cell tuft cells viral infection Wnt [DOI] 10.7554/eLife.78217 PMC 바로가기
The choroid plexus and its role in the pathogenesis of neurological infectionsArticle Published on 2022-09-102022-11-15 Journal: Fluids and Barriers of the CNS [Category] SARS, 치료기술, 치료제, [키워드] Activation Alter bidirectional Blood–CSF barrier Borrelia Borrelia burgdorferi Brain Cell cells cellular response Central nervous system cerebrospinal fluid changes in chemotaxis choroid Choroid plexus circulating CNS CNS disorder cytokine dendritic cells develop Diseases disorder driving epithelia epithelial epithelial cell function greater highlight homeostasis homing hydrocephalus Immune cell immune cells immune response Immunity immunological Including induce Infection infections Inflammation inflammatory signal John Cunningham virus junction knowledge less macrophages Neuroinflammation neurological pathogen Pathogenesis Pathogens pharmacological intervention promote provide Research SARS-CoV-2 shown T cells target these cell virus Zika virus [DOI] 10.1186/s12987-022-00372-6 PMC 바로가기