Single-residue linear and conformational B cell epitopes prediction using random and ESM-2 based projectionsProblem Solving Protocol Published on 2024-03-142024-09-05 Journal: Briefings in Bioinformatics [Category] update2024, [키워드] BiLSTM embedding Epitope prediction machine learning protein structure [DOI] 10.1093/bib/bbae084 PMC 바로가기 [Article Type] Problem Solving Protocol
A robust deep learning workflow to predict CD8 + T-cell epitopesarticle Published on 2023-09-132024-09-05 Journal: Genome Medicine [Category] update2024, [키워드] CD8 + T-cell epitopes computational immunology deep learning Epitope prediction immunogenicity MHC binding Neoepitope identification Self-antigen tolerance Thymic selection transfer learning vaccine candidates [DOI] 10.1186/s13073-023-01225-z PMC 바로가기 [Article Type] article
Recent trends in next generation immunoinformatics harnessed for universal coronavirus vaccine designReview Published on 2023-03-012023-07-09 Journal: Pathogens and global health [Category] COVID19(2023년), [키워드] characterization database Epitope prediction human coronavirus immunoinformatics peptide vaccine vaccine target. [DOI] 10.1080/20477724.2022.2072456 PMC 바로가기 [Article Type] Review
Designing multi-epitope monkeypox virus-specific vaccine using immunoinformatics approachArticle Published on 2023-01-012023-06-10 Journal: Journal of infection and public health [Category] Fulltext, 원숭이두창, [키워드] codon optimization Epitope prediction expression analysis molecular docking Monkeypox virus Vaccine [DOI] 10.1016/j.jiph.2022.11.033 PMC 바로가기
CAVES: A Novel Tool for Comparative Analysis of Variant Epitope SequencesCAVES: 변이 에피토프 서열의 비교 분석을 위한 새로운 도구Article Published on 2022-05-262022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] Accuracy Analysis antigenic antigenic variation approach bioinformatics categories category coding Comparative Comparative analysis Comparative genomics comparison Computational biology database epitope Epitope prediction Epitopes Evolution fraction Github graphical user interface IEDB immune IMPROVE novel open-source software pathogen Pathogens peptide peptides reducing required SARS-CoV-2 variant SARS-CoV-2 variants sequence Sequence analysis source code speed subject test dataset therapeutic user interface Vaccine variant window [DOI] 10.3390/v14061152 PMC 바로가기 [Article Type] Article
An integrated in silico based subtractive genomics and reverse vaccinology approach for the identification of novel vaccine candidate and chimeric vaccine against XDR Salmonella typhi H58article Published on 2022-03-312024-09-01 Journal: Genomics [Category] 살모넬라증, [키워드] Chimeric vaccine Epitope prediction reverse vaccinology Salmonella typhi XDR H58 vaccine target [Article Type] article
Immunodominant and Neutralizing Linear B-Cell Epitopes Spanning the Spike and Membrane Proteins of Porcine Epidemic Diarrhea VirusImmunology Published on 2022-01-192022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, MERS, [키워드] amino acid sequence B-cell epitope cause Complete consensus sequence contribute demonstrated disease ELISA testing epidemic diarrhea epitope Epitope prediction genetic diversity greater group high mortality rate identify immune stimulation immunodominant epitope immunoinformatics insight linear linear B-cell epitope M protein membrane membrane protein NCBI database neutralization Neutralizing neutralizing epitope nine offer PEDV peptide peptide-based immunoassays Porcine epidemic diarrhea virus predicted profile Protein Proteins provided retrieved S2 subunit sera Seven Spike protein strain Strains the S protein the Spike Vaccine virus Virus neutralization [DOI] 10.3389/fimmu.2021.785293 PMC 바로가기 [Article Type] Immunology
Origin, phylogeny, variability and epitope conservation of SARS-CoV-2 worldwide전 세계적으로 SARS-CoV-2의 기원, 계통 발생, 가변성 및 에피토프 보존Article Published on 2021-10-152022-09-11 Journal: Virus research [Category] SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Amino acid amino acid change amino acid changes analyzed antibodies caused Cluster Comparative genomics conserved contributed coronavirus Coronavirus comparative genomics coronavirus disease Coronavirus disease 2019 COVID-19 distribution Efficacy epitope epitope conservation Epitope prediction Epitopes Evidence evidence of favor GenBank Genome genomes Geographic distribution GISAID database hotspot identify Multiple Mutation N protein nucleotide ORF origin pandemic pangolin Phylogeny predicted primary structure Protein Recombination Region RNA virus SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 genomics severe acute respiratory syndrome Coronavirus Single nucleotide variant SNV SNVs spike spike gene spike glycoprotein Spike protein structural proteins target targets the spike protein triggered Vaccine vaccine efficacy Variability variable variant viral genome virus VoC VOCs [DOI] 10.1016/j.virusres.2021.198526 PMC 바로가기 [Article Type] Article
Immunoinformatics approach for multi-epitope vaccine design against P. falciparum malariaarticle Published on 2021-08-312024-09-01 Journal: Infection, Genetics and Evolution [Category] 말라리아, [키워드] Epitope prediction immunoinformatics Infectious disease malaria Vaccine [Article Type] article
Infectious disease mRNA vaccines and a review on epitope prediction for vaccine designArticle Published on 2021-06-042023-07-01 Journal: Briefings in functional genomics [Category] SARS, [키워드] COVID-19 Epitope prediction machine learning mRNA vaccines other infectious diseases [DOI] 10.1093/bfgp/elab027 PMC 바로가기