MultiTEP-Based Vaccines Targeting SARS-CoV-2 Spike Protein IgG Epitopes Elicit Robust Binding Antibody Titers with Limited Virus-Neutralizing ActivityArticle Published on 2024-06-202024-09-05 Journal: Pathogens [Category] update2024, [키워드] COVID-19 epitope vaccines immunogenicity MultiTEP platform neutralization Spike protein [DOI] 10.3390/pathogens13060520 PMC 바로가기 [Article Type] Article
Genome-based prediction of cross-protective, HLA-DR-presented epitopes as putative vaccine antigens for multiple Bordetella species유전체 기반의 교차 보호 HLA-DR 제시 에피토프 예측을 다수의 보르데텔라 종에 대한 잠재적 백신 항원으로서Article Published on 2024-01-112024-08-25 Journal: Microbiol Spectr [Category] 백일해, [키워드] Bordetella pertussis cross-protection epitope vaccines immunogenicity
Rarely Recognized Antibody Diversification in Covid-19 Evolution to Counteract Advanced SARS-CoV-2 Evasion Strategies, and Implications for Prophylactic TreatmentPhysiology Published on 2021-08-032022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] adaptive Amino acid amino-acid sequence dependency antibody antibody diversification B-cell candidate component consequence COVID-19 Critical defined determinant disease effective elicited epitope vaccines Evidence Evolution example explain gene sequence Genome glycosylation help highlight human cell humoral immune response hypothese immune response immune system Immunity immunogenic peptides immunomodulatory effects Implications Interpretation mechanism natural infection neutralizing antibody pandemic patient groups platform post-translational modification prophylactic treatment rarely recognized immune responses Safe SARS-CoV-2 SARS-COV-2 infection sequence somatic mutations Structural variation the vaccine translational Trial unique Vaccine design virus [DOI] 10.3389/fphys.2021.624675 PMC 바로가기 [Article Type] Physiology