The Effect of the COVID-19 Pandemic on Non–COVID-19 Deaths: Population-Wide Retrospective Cohort StudyOriginal Paper Published on 2024-02-132024-09-05 Journal: JMIR Public Health and Surveillance [Category] update2024, [키워드] avoidance Causal inference Cohort COVID-19 death death rate death toll emergency department Epidemiology excess Excess death Health care health care avoidance Hong Kong hospital hospital avoidance behavior hospital care Impact Mortality Population [DOI] 10.2196/41792 PMC 바로가기 [Article Type] Original Paper
Mediators of Obesity Do Not Influence SARS-CoV-2 Infection or Activation of Primary Human Lung Microvascular Endothelial Cells In Vitro비만 매개체는 SARS-CoV-2 감염 또는 시험관 내 1차 인간 폐 미세혈관 내피 세포 활성화에 영향을 미치지 않습니다Article Published on 2022-06-282022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료기술, [키워드] activated Activation addition Adhesion Molecule adipokines adipose Adipose tissue Alter Cell cells clinical clinical observations COVID-19 Critically ill driving dysfunction E-selectin endothelial endothelial activation Endothelial cell endothelial cells Endothelial dysfunction evidenced exacerbate excess exposure to expression fat Human human lung ICAM-1 IL-6 Incubation individuals induce Infection Inflammation Inflammatory Inflammatory cytokine Inflammatory response Inflammatory responses influence initiated lack Leptin lung Lungs mechanism mediator mounted obese obese COVID-19 patients obesity observation other organs outcome phenotype plasma pro-inflammatory produced virus required response SARS-CoV-2 SARS-CoV-2 entry receptor SARS-COV-2 infection selectin severe disease shown susceptibility susceptibility to infection susceptible systemic level tested tissue VCAM-1 Viral protein Viral proteins virus visceral with COVID-19 [DOI] 10.3389/fimmu.2022.879033 PMC 바로가기 [Article Type] Article
Heparanase Is a Putative Mediator of Endothelial Glycocalyx Damage in COVID-19 – A Proof-of-Concept Study헤파라나제는 COVID-19에서 내피 글리코칼릭스 손상의 추정 매개체입니다 - 개념 증명 연구Article Published on 2022-06-102022-09-12 Journal: Frontiers in Immunology [Category] MERS, 진단, [키워드] atomic Bacterial sepsis changes in Coronavirus disease 2019 correlated COVID-19 COVID-19 patient cultured cell damage dimension disease endothelial endothelial glycocalyx (EG) enzyme excess experiments glycocalyx Heparanase heparanase (HPSE) heparin HPSE immunofluorescence inhibition Injury marker mediator Microscopy plasma plasma sample prevented Protective protective effect serum shown translational Vascular endothelium vessel videomicroscopy. [DOI] 10.3389/fimmu.2022.916512 PMC 바로가기 [Article Type] Article
Commentary on “Poor evidence for host-dependent regular RNA editing in the transcriptome of SARS-CoV-2”"SARS-CoV-2의 전사체에서 숙주 의존적 정규 RNA 편집에 대한 불충분한 증거"에 대한 논평Article Published on 2022-05-012022-09-11 Journal: Journal of applied genetics [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] ADAR ADARs Analysis APOBEC APOBECs cellular RNA changes criticism Evidence excess experimental validation explain form genetic change genetic variability Host Hypothesis in viral involved RNA RNA editing SARS-CoV-2 SARS-CoV-2 transcriptome shown similarities similarity the SARS-CoV-2 Transcriptome Variability viral genome viral replication Viral RNA viruses while [DOI] 10.1007/s13353-022-00688-x PMC 바로가기 [Article Type] Article
Effect of plasma exchange on COVID-19 associated excess of von Willebrand factor and inflammation in critically ill patients Research Published on 2022-03-212022-10-05 Journal: Scientific Reports [Category] 치료법, [키워드] accompanied acute respiratory distress ADAMTS13 Antigen ARDS benefit C-reactive protein clinical parameter COVID-19 Critically ill patient cytokine Effect excess expiratory hospitals immunothrombosis Inflammation Inflammatory Inflammatory cytokine inflammatory state investigated lactate dehydrogenase monocyte chemotactic protein-1 on mechanical ventilation parameter parameters pathogenesis of COVID-19 Patient patients plasma plasma exchange Pneumonia positive reduce reduced reduction resulting sequence severe COVID-19 significant decrease significant increase significantly syndrome therapeutic option therapy vasculature Ventilation von Willebrand factor were assessed [DOI] 10.1038/s41598-022-08853-2 [Article Type] Research
Excess all-cause deaths stratified by sex and age in Peru: a time series analysis during the COVID-19 pandemicEpidemiology Published on 2022-03-102022-10-28 Journal: BMJ Open [Category] COVID-19, Fulltext, MERS, [키워드] age age and sex Analysis Annual Complete COVID-19 COVID-19 pandemic cross-sectional study death death rate deaths distribution eight epidemiological Epidemiology excess expected expected mortality Infectious diseases men Meta-analysis Ministry of Health Mortality mortality data occurred outcome measure participant public health random-effect Region regions Result setting Seven Sex stratified by sex women [DOI] 10.1136/bmjopen-2021-057056 PMC 바로가기 [Article Type] Epidemiology
Heat-related mortality amplified during the COVID-19 pandemicObservational Study Published on 2022-03-012022-10-05 Journal: International journal of biometeorology [Category] SARS, 임상, [키워드] addressed Admission amplification amplified cause caused changes in collected COVID-19 COVID-19 pandemic death excess expected expressed extreme fraction healthcare facility healthcare service Healthcare system Heatwaves High-resolution lockdown magnitude measure Mortality mortality data pandemic performed Portugal prevented Public public health reached reported shown statistical model temperature virus while [DOI] 10.1007/s00484-021-02192-z PMC 바로가기 [Article Type] Observational Study
Excess risk and clusters of symptoms after COVID-19 in a large Norwegian cohortCovid-19 Published on 2022-02-252022-10-31 Journal: European Journal of Epidemiology [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] 95% CI adjusted relative risk breath calculate Child Cluster cognitive Cohort cohort study correlation cough COVID COVID-19 COVID-19 pandemic COVID-19 patient Depression Dizziness excess explained Factor father fatigue identify Infection less mechanism memory MoBa moderate non-infected Occurrence participant Post-acute sequelae Psychological question Registered reported risk SARS-CoV-2 SARS-COV-2 infection strongly related subject subjects supplementary material swing Symptom Symptoms syndrome The Norwegian Mother, Father and Child Cohort Study uninfected [DOI] 10.1007/s10654-022-00847-8 PMC 바로가기 [Article Type] Covid-19
Rethinking COVID-19 and Beyond: Prevention, Remedies, and RecoveryPublic Health Published on 2022-02-232022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, [키워드] accompanied adverse effects carbohydrate change chronic disease Chronic diseases Comorbidity COVID-19 COVID-19 infection death excess fat glycocalyx Health healthcare illness immune function Immunity Implementing increased the risk Infection Inflammation Inflammatory Inflammatory diseases involved Malnutrition measure Modification obesity overfat pandemic prevention public health reactive reported response Rethinking rising risk Safe sugar vaccination Vitamin D while with COVID-19 [DOI] 10.3389/fpubh.2022.748498 PMC 바로가기 [Article Type] Public Health
Disparities in Excess, All-Cause Mortality among Black, Hispanic, and White Veterans at the U.S. Department of Veterans Affairs during the COVID-19 PandemicArticle Published on 2022-02-182022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] Affair affected age and gender all-cause mortality all-cause mortality rate black calculated Care change COVID-19 COVID-19 pandemic death Department disparity examined excess Factor group groups highest Hispanic increase in mitigate Mortality occurred Older pandemic Racial Racial disparities Rate receiving Research SMRs understanding veteran veterans white [DOI] 10.3390/ijerph19042368 PMC 바로가기 [Article Type] Article