Understanding the dynamic relation between wastewater SARS-CoV-2 signal and clinical metrics throughout the pandemicArticle Published on 2022-12-202022-11-16 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha variant clinical testing Community complementary COVID-19 COVID-19 disease COVID-19 incidence deaths Delta VOC disease disease incidence Effectiveness expected Hospital admissions ICU admissions immunization incidence Infection Laboratory positive cases Metrics moderate omicron pandemic Population positive SARS-CoV-2 shown Spread Surveillance understanding vaccination vaccination rate Vaccine virulence VoC waned wastewater weakened widespread wildtype WWS. [DOI] 10.1016/j.scitotenv.2022.158458 PMC 바로가기
The impact of COVID-19 non-pharmaceutical interventions on HIV care continuum in China: An interrupted time series analysisResearch article Published on 2022-12-012022-10-05 Journal: The Lancet Regional Health - Western Pacific [Category] 변종, [키워드] 95% CI affected Analysis Antiretroviral therapy ART Care CD4 count CD4 counts CD4+ T cell China collected continuum COVID-19 decrease diagnose diagnoses Diagnosis disease early stage effort evaluate expected finding foundation funding HIV hospital implementation increase in Infectious disease Interrupted time series analysis interval Intervention maintain majority male median time natural non-pharmaceutical interventions (NPIs) NPI NPIs occurred outcome outcomes Poisson Prophylaxis public health emergency reached Region Regression model Science study period time interval time intervals Transmission were recorded [DOI] 10.1016/j.lanwpc.2022.100569 [Article Type] Research article
A SARS-CoV-2 vaccine based on conjugation of SARS-CoV-2 RBD with IC28 peptide and mannanArticle Published on 2022-12-012022-11-15 Journal: International journal of biological macromolecules [Category] COVID19(2023년), SARS, 진단, [키워드] ACE2 adjuvant Antibody titer Antigen antigenicity Bacterial cause cellular immunity COVID-19 COVID-19 pandemic cytokine develop domain E. coli effective effective vaccine elicit elicited expected expressed feasibility humoral IFN-γ IL-10 IL-5 IMPROVE Interaction Ligand mannan neutralization neutralizing antibody organs peptide polysaccharide RBD RBD-specific IgG SARS-CoV-2 SARS-CoV-2 RBD SARS-CoV-2 spike protein SARS-CoV-2 vaccine SARS-CoV-2. sera severe respiratory disease Th2-type Toxicity Vaccine Vaccine development viral infection virus [DOI] 10.1016/j.ijbiomac.2022.09.180 PMC 바로가기
Validation of SARS-CoV-2 pooled testing for surveillance using the Panther Fusion® system: Impact of pool size, automation, and assay chemistryArticle Published on 2022-11-072022-11-15 Journal: PLoS ONE [Category] SARS, 진단, 치료기술, [키워드] approach assays authorization automated conducted cut-off threshold cycle threshold decrease demonstrated diagnostic Emergency evaluated expected FDA FIVE generate Impact less limit of detection lowering nasopharyngeal sample nucleic acid amplification positive positive sample resources SARS-CoV-2 SARS-CoV-2 RNA sensitivity specificity specimen Surveillance surveillance testing System tested validation was used [DOI] 10.1371/journal.pone.0276729 PMC 바로가기
Antiviral efficacy of cerium oxide nanoparticlesArticle Published on 2022-11-052022-11-15 Journal: Scientific Reports [Category] SARS, 치료제, [키워드] Antiviral antiviral activity antiviral efficacy candidate Concentration coronavirus SARS-CoV-2 cytotoxicity decrease Effect Efficacy evidenced expected gastroenteritis highest Influenza virus Ion mechanism MS2 bacteriophage Nanomaterial no decrease non-enveloped virus nonspecific plaque forming unit Registered released sensitivity significantly lower tested virus virus viruses were assessed [DOI] 10.1038/s41598-022-23465-6 PMC 바로가기
Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics InitiativeArticle Published on 2022-11-032022-11-15 Journal: PLoS Genetics [Category] SARS, 변종, 진단, [키워드] analysis Analysis association chromosome Cohort controls country COVID-19 Deleterious disease expected Genetic genetics Genome-wide association study identify increase in initiative loci outcome outcomes Pathogenesis performed rare variant Result severe disease Support susceptibility the SARS-CoV-2 TLR7 Toll-like receptor variant whole-genome sequencing with COVID-19 [DOI] 10.1371/journal.pgen.1010367 PMC 바로가기
Effects of the COVID-19 Pandemic on Incidence and Epidemiology of Catheter-Related Bacteremia, SpainArticle Published on 2022-11-012022-11-16 Journal: Emerging Infectious Diseases [Category] 치료기술, [키워드] 95% CI acute respiratory syndrome Bacteremia Bacteria calculated Care Catalonia catheter-related bacteremia coronavirus coronavirus disease COVID-19 COVID-19 pandemic diagnosed Effect effort expected hospital Hospital admissions incidence rate increase in Patient patient safety predicted quality of care Regression model respiratory infections SARS SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Spain stratified viruses zoonoses zoonoses. [DOI] 10.3201/eid2811.220547 PMC 바로가기
Targeting SARS-CoV-2 papain-like protease in the postvaccine eraArticle Published on 2022-11-012022-11-15 Journal: Trends in pharmacological sciences [Category] SARS, 치료제, [키워드] approval artificial intelligence Compound computer-aided drug design COVID-19 Critical direct-acting antiviral drug drugs expected global healthcare Host innate immune response methodology Papain-like protease PLPro Rapid responses SARS-CoV-2 SARS-CoV-2 protein Small molecules small molecules. targeting therapeutic target Vaccine viral replication waning immunity while [DOI] 10.1016/j.tips.2022.08.008 PMC 바로가기
SARS-CoV-2 dual infection with Delta and Omicron variants in an immunocompetent host: a case reportArticle Published on 2022-11-012022-11-15 Journal: International Journal of Infectious Diseases [Category] SARS, 변종, 치료기술, [키워드] Admission Analysis Case report caused Contamination coronary syndrome COVID-19 Delta detect discharged dominant variant Dual infection expected highlight hospital Hospitalized Infection Lineage Mild symptom omicron Patient positive test result reported SARS-CoV-2 SARS-CoV-2 infections SARS-CoV-2 RNA sequence sequenced Sequencing Single-genome sequencing. the SARS-CoV-2 variant variants virus whole genome [DOI] 10.1016/j.ijid.2022.08.027 PMC 바로가기
Fear learning and generalization during pandemic fear: How COVID-19-related anxiety affects classical fear conditioning with traumatic film clipsResearch article Published on 2022-11-012022-10-05 Journal: Journal of psychiatric research [Category] 바이오마커, 임상, 치료기술, [키워드] acquisition Affect Anxiety anxiety disorders classical clinical trial collected conditioned connection contribute COVID-19 COVID-19 pandemic Effect expected experiment fear Fear conditioning Fear generalization Final greater Health healthy higher risk impairment increase in investigated mechanism pandemic Pandemic fear participant Psychological well-being recent risk factor significantly Stress Symptom [DOI] 10.1016/j.jpsychires.2022.07.068 [Article Type] Research article