Empirical Quantification of Predictive Uncertainty Due to Model Discrepancy by Training with an Ensemble of Experimental Designs: An Application to Ion Channel Kineticsarticle Published on 2023-11-242024-09-05 Journal: Bulletin of Mathematical Biology [Category] update2024, [키워드] discrepancy experimental design ion channel mathematical model misspecification Uncertainty quantification [DOI] 10.1007/s11538-023-01224-6 PMC 바로가기 [Article Type] article
Use of research electronic data capture (REDCap) in a sequential multiple assignment randomized trial (SMART): a practical example of automating double randomizationarticle Published on 2023-07-062024-09-05 Journal: BMC Med Res Methodol [Category] update2024, [키워드] Adaptive interventions Automation experimental design randomization Randomized controlled trials (RCT) Reducing human errors Research Electronic Data capture (REDCap) Sequential multiple assignment Randomized Trial (SMART) [DOI] 10.1186/s12874-023-01986-6 PMC 바로가기 [Article Type] article
Modeling COVID-19 disease processes by remote elicitation of causal Bayesian networks from medical expertsarticle Published on 2023-03-292024-09-05 Journal: BMC Med Res Methodol [Category] update2024, [키워드] Bayesian network Causal model COVID-19 DAG DBN Decision support experimental design expert elicitation pathophysiology [DOI] 10.1186/s12874-023-01856-1 PMC 바로가기 [Article Type] article
Interleukin-18 and COVID-19Original Paper Published on 2022-12-162022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, SARS, [키워드] 95% CI 95% confidence interval Analysis applied association conducted Coronavirus Disease (COVID)-19 COVID-19 cytokine estimate Evolutionary biology experimental design Exploratory analysis Genetic Genome-wide association study genome-wide significant hospitalised IFN Immunity interferon interferon gamma Interleukin-18 investigated less liberal lower risk Mendelian randomisation Odds ratio precursor predicted predictor predictors Prevent randomisation severe COVID-19 severity Standard deviation vulnerability was related with COVID-19 [DOI] 10.1017/S0950268821002636 PMC 바로가기 [Article Type] Original Paper
Art-science multidisciplinary collaborations to address the scientific challenges posed by COVID-19Article Published on 2022-12-012022-11-15 Journal: Annals of Medicine [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Algorithm approach art-based method Asymptomatic individuals Contagion contribute coronavirus COVID COVID-19 COVID-19 pandemic develop Diagnosis Effect experimental design host immunity Human immunology incidence increase Interaction Interpretation Mixed-methods Modification Molecular biology Multidisciplinary nutritional intervention pandemic Pandemics Perspective promote Protean art Protective protective mechanism reduce Research response to vaccination risk SARS-CoV-2 variant SARS-CoV-2 virus Surveillance translate transmission of SARS-CoV-2 Vaccine vector virus virus transmission zoonotic disease [DOI] 10.1080/07853890.2022.2123557 PMC 바로가기
Effectiveness of prone position in acute respiratory distress syndrome and moderating factors of obesity class and treatment durations for COVID-19 patients: A meta-analysisResearch article Published on 2022-10-012022-10-05 Journal: Intensive & critical care nursing [Category] COVID19(2023년), SARS, 치료법, [키워드] 95% CI 95%CI acute respiratory distress acute respiratory distress syndrome Analysis article body mass index calculated CINAHL conducted coronavirus 2 COVID-19 COVID-19 patient effect size Effectiveness eligible experimental design Factor Final Invasive mechanical ventilation mean difference Meta-analysis methodology NCBI non-invasive ventilation obesity objective oxygen saturation PaO2 paO2/fiO2 Patient patients patients with COVID-19 prone Prone position prone positioning ProQuest Respiratory failure Result SARS-CoV-2 secondary outcome significantly SpO2 statistically significant syndrome Treatment Web of Science [DOI] 10.1016/j.iccn.2022.103257 [Article Type] Research article
Mathematical Modeling to Guide Experimental Design: T Cell Clustering as a Case StudyArticle Published on 2022-08-172024-08-29 Journal: Am J Roentgenol Radium Ther [Category] 말라리아, [키워드] Clustering experimental design liver mathematical modeling Plasmodium sporozoites power analysis Stochastic simulations T cells
Reciprocal perspective as a super learner improves drug-target interaction prediction (MUSDTI) Research Published on 2022-08-022022-10-05 Journal: Scientific Reports [Category] 신약개발, [키워드] binary classification binding affinity computation computational method Course Critical database Davis Diseases Drug discovery drug-target drug-target interaction effort experiment experimental design generate IMPROVE interact Interaction Meta outperform Perspective physically predictor Protein public health Reciprocal student transfer [DOI] 10.1038/s41598-022-16493-9 [Article Type] Research
Effects of Narrative Messages on Key COVID-19 Protective Responses: Findings From a Randomized Online ExperimentRandomized Controlled Trial Published on 2022-07-012022-10-04 Journal: American journal of health promotion : AJHP [Category] 임상, [키워드] Administered assigned baseline benefit communication condition COVID-19 disease disease management drug Effect Effectiveness experimental design finding Health health communications individual Intention Interaction investigated less Measures message misinformation MTurk multivariable narrative narratives. outcomes Perception positive Randomly receive recommendations recruited social distancing unproven treatment unproven treatments vaccination Vaccine were assessed [DOI] 10.1177/08901171221075612 PMC 바로가기 [Article Type] Randomized Controlled Trial
Replication kinetics and infectivity of SARS-CoV-2 variants of concern in common cell culture models일반적인 세포 배양 모델에서 우려되는 SARS-CoV-2 변이체의 복제 동역학 및 감염성Article Published on 2022-04-262022-09-11 Journal: Virology Journal [Category] COVID19(2023년), SARS, 변종, [키워드] African airway Alpha antibody B.1.617.2 Beta Caco-2 Calu Calu-3 caused Cell culture cell culture supernatant cell culture supernatants cell line cell lines Colon concern conducted coronavirus different time point different time points Drug screening epidemiological epithelial experimental design FIVE Genome green growth human cell line human cell lines immunological in viral Infection information investigated kidney Kinetics mutations omicron pandemic pathogenic Post-infection Propagation provide replication kinetics Research researcher SARS-CoV-2 SARS-CoV-2 variant several variants Support the SARS-CoV-2 Vero Vero E6 viral particle Viral particles viral replication kinetics Viral RNA virus virus isolation viruses VoC VOC. VOCs [DOI] 10.1186/s12985-022-01802-5 PMC 바로가기 [Article Type] Article