Fighting fibrosis News Published on 2022-08-012022-10-05 Journal: Nature biotechnology [Category] 바이오마커, [키워드] fibrosis Fighting [DOI] 10.1038/s41587-022-01412-0 [Article Type] News
Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer응급실 스트레스 상태의 급성기에 대응하기 위해 항혈소판제 티클로피딘의 용도 변경: 코로나바이러스 감염 및 암 퇴치를 위한 기회Article Published on 2022-07-062022-09-11 Journal: Molecules [Category] COVID19(2023년), SARS, 신약개발, [키워드] Achille agent antiplatelet Antiplatelet agent approach approved drugs attribute Cancer Cancer cells Cell Coronavirus infections Coronavirus-2 COVID-19 demonstrated Endoplasmic reticulum endoplasmic reticulum (ER) ER membranes ER stress exacerbating Fighting heel homeostasis life cycle Metastasis Modification modulation opportunity P2Y12 P2Y12 inhibitors pathological conditions Perturbation phase promote receptor representing repurposing responsible SARS Coronavirus SARS-CoV-2 sigma sigma 1 receptor (S1R) terminal UPR the disease therapeutic intervention Therapies ticlopidine ticlopidine. Tumor tumor growth unfolded protein response UPR viral glycoprotein viral glycoproteins viral infection viral infections viral life cycle [DOI] 10.3390/molecules27144327 PMC 바로가기 [Article Type] Article
Comparison Between China and Brazil in the Two Waves of COVID-19 Prevention and ControlCOVID-19 예방 및 통제의 두 가지 물결에서 중국과 브라질의 비교Article Published on 2022-06-012022-09-11 Journal: Journal of Epidemiology and Global Health [Category] COVID19(2023년), SARS, 변종, [키워드] Brazil China conditions confirmed case confirmed cases Containment Containment measure Containment strategy Control cooperation country COVID-19 COVID-19 case COVID-19 cases cumulative cumulative death rate death case death rate effective Effectiveness Epidemic evaluate Factors Fighting indicate Intervention long-lasting measure Meteorological factor Mitigation Mitigation strategy much higher Multiple mutant strain Mutant strains National Perspective Policy Policy evaluation. premise prevention Prevention and control provide reached situation spread of COVID-19 the epidemic vaccination Wave [DOI] 10.1007/s44197-022-00036-6 PMC 바로가기 [Article Type] Article
Fighting SARS-CoV-2 with structural biology methods Comments & Opinion Published on 2022-04-082022-10-05 Journal: Nature methods [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Fighting SARS-CoV-2 [DOI] 10.1038/s41592-022-01448-9 [Article Type] Comments & Opinion
Fighting the SARS-CoV-2 pandemic requires a global approach to understanding the heterogeneity of vaccine responses Reviews Published on 2022-02-242022-10-05 Journal: Nature Immunology [Category] COVID19(2023년), SARS, 비임상, [키워드] acute respiratory syndrome Adaptive immune response adaptive immune responses adjuvant age approach cellular contribute coronavirus Coronaviruses effective Efficacy environmental factor Factor failure Fighting Genetic geographical location heterogeneity humoral immune response Humoral immunity immune protection impair innate immune innate immune response innate immune system long-lived plasma cell mechanism memory T cell metabolite microbiome composition MOST pandemic SARS-CoV-2 Sex the SARS-CoV-2 Vaccine vaccine response Vaccines vectors [DOI] 10.1038/s41590-022-01130-4 [Article Type] Reviews
Fighting Fire with Fire: Immunogenicity of Viral Vectored Vaccines against COVID-19화재로 화재 퇴치 : Covid-19에 대한 바이러스 성 벡터 백신의 면역 원성Review Published on 2022-02-122022-09-01 Journal: Viruses [Category] COVID19(2023년), Fulltext, MERS, SARS, 비임상, 임상, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody approved breadth breath caused cellular Clinical studies coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 distribution effective elicited Fighting fire global pandemic globe humoral immune correlate immune correlates immune response immune responses immunogenicity innate immune response limitation mass vaccination morbidity Mortality offer provide rationale reduce regimens respiratory Safe SARS-CoV-2 severe acute respiratory syndrome Coronavirus T cells Transmission vaccination Vaccine Viral viral vectored vaccine viral vectored vaccines viral vectors [DOI] 10.3390/v14020380 PMC 바로가기 [Article Type] Review
Antiviral Effects of Artemisinin and Its Derivatives against SARS-CoV-2 Main Protease: Computational Evidences and Interactions with ACE2 Allelic VariantsArticle Published on 2022-01-222022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] ACE2 ACE2 allelic variants acute respiratory syndrome allelic variant allelic variants antiviral activity Artemisinin binding affinity binding interactions Bioavailability complex Compound computational approach coronavirus coronavirus disease COVID-19 Cys145 dependent on derivative drug-likeness Effect enzyme evaluate explain Fighting Frame Hydrogen bond in silico Infection inhibit Interaction investigated main protease (Mpro) manifested molecular molecular dynamics MPro outlined pharmacokinetic protease recent reported Research residue SARS-CoV-2 SARS-COV-2 infection selected Spike protein stability the SARS-CoV-2 trajectory was recorded [DOI] 10.3390/ph15020129 PMC 바로가기 [Article Type] Article
Why the World Should Not Follow the Failed United States Model of Fighting Domestic HungerCommentary Published on 2022-01-122022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] America country COVID-19 COVID-19 pandemic develop empowerment Fighting food banks food insecurity Government healthcare help hunger measure Model organization outcome pandemic provide raise reducing robust survival the United State United State [DOI] 10.3390/ijerph19020814 PMC 바로가기 [Article Type] Commentary
Human Organoids as a Promising Platform for Fighting COVID-19Review Published on 2022-01-012022-10-29 Journal: International Journal of Biological Sciences [Category] COVID-19, SARS, [키워드] acute respiratory syndrome basic cell tropism clinical trial coronavirus coronavirus disease COVID-19 disease pathogenesis Disease progression Drug screening effective therapy ex vivo model facilitate Fighting global pandemic highlight Human in viral Infection molecular mechanism morbidity and mortality Organoid pandemic Pathogenesis platform potential therapeutic agent potential therapy public health regimens Replication Research SARS-CoV-2 triggered understanding vaccination viral invasion virus [DOI] 10.7150/ijbs.64993 PMC 바로가기 [Article Type] Review
Fighting the pandemic with collaboration at heart: Report from cardiologists in a COVID-19-dedicated Portuguese intensive care unit협력을 중심으로 전염병 퇴치: COVID-19 전담 포르투갈 집중 치료실의 심장 전문의의 보고서Article Published on 2021-12-012022-09-11 Journal: Revista portuguesa de cardiologia [Category] SARS, 치료기술, [키워드] Adult patients age analyzed cardiac marker Cardiac markers Cardiologia Cardiology cardiovascular risk Care changed coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 prognosis Cuidados intensivos Cuidados multidisciplinares de novo Decision making died discharged dysfunction dyslipidemia English Extra-corporeal membrane oxygenation Fighting followed by hypertension ICU intensive care male Manifestations mechanical ventilation membrane mobilization Multidisciplinary care myocardial injury N-terminal N-terminal pro-B-type natriuretic peptide Nova NT-proBNP one patient Oxigenação por membrana extracorporal pandemic Patient Patient care patients with COVID-19 pelo peptide pro-B-type natriuretic peptide report required Respiratory illness severe COVID-19 Spread Takotsubo the disease Vasopressor vasopressor support [DOI] 10.1016/j.repce.2021.11.009 PMC 바로가기 [Article Type] Article