Novel Synthetic Lipopeptides as Potential Mucosal Adjuvants Enhanced SARS-CoV-2 rRBD-Induced Immune ResponseSARS-CoV-2 rRBD 유도 면역 반응을 향상시키는 잠재적 점막 보조제로서의 새로운 합성 리포펩티드Article Published on 2022-03-092022-09-12 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, [키워드] activity adjuvant adjuvants Affect agonist agonists Bacterial BALF candidate vaccine charged residue COVID-19 vaccine CSK cytotoxicity Effect enhanced evaluated exhibited Figuring IgA IgG immune response immunized in vitro induce investigated lipopeptide lipoprotein mimicking mucosal N-terminal nasal novel OVA peptide Potential promote RBD residue response rRBD SARS-CoV-2 SARS-CoV-2 neutralizing antibody SARS-CoV-2 rRBD sequence sera serum significantly increased significantly lower Structure Structure-activity relationship suggested Support support vector machine SVM synthetic the SARS-CoV-2 TLR2 Vaccine vaccine adjuvant [DOI] 10.3389/fimmu.2022.833418 PMC 바로가기 [Article Type] Article
Aerosol transmission, an indispensable route of COVID-19 spread: case study of a department-store clusterResearch Article Published on 2020-12-252022-10-31 Journal: Frontiers of Environmental Science & Engineering [Category] COVID-19, [키워드] activities aerosol transmission analyzed Characteristics China Cluster COVID-19 Department dependent on environmental condition environmental factor Epidemiologic characteristic epidemiological Factor Figuring Hospitalization Incubation indicated Infection route Isolation median occur outbreak outbreak sites Patient released respiratory tract RNA SARS-CoV-2 Spread SRAS-CoV-2 temperature the SARS-CoV-2 Transmission unique Ventilation widespread with COVID-19 [DOI] 10.1007/s11783-021-1386-6 PMC 바로가기 [Article Type] Research Article
Mitochondrial-targeted ubiquinone: A potential treatment for COVID-19Research article Published on 2020-11-012022-10-05 Journal: Medical Hypotheses [Category] 치료법, [키워드] alleviate antioxidant characterized COVID-19 COVID-19 patient Cytokine storm disease dysregulated immune response dysregulation Effect Evidence Figuring immune dysregulation Inflammatory cytokine mitochondrial dysfunction MitoQ Potential treatment recent responsible SARS-CoV-2 severe COVID-19 Support T cell T cell exhaustion therapy [DOI] 10.1016/j.mehy.2020.110161 [Article Type] Research article