Impact of Concomitant Thiopurine on the Efficacy and Safety of Filgotinib in Patients with Ulcerative Colitis: Post Hoc Analysis of the Phase 2b/3 SELECTION StudyOriginal Article Published on 2024-06-292024-09-04 Journal: Journal of Crohn's and Colitis [Category] 대상포진, [키워드] filgotinib Thiopurine ulcerative colitis [DOI] 10.1093/ecco-jcc/jjad201 PMC 바로가기 [Article Type] Original Article
Matching-Adjusted Indirect Comparisons of Filgotinib vs Vedolizumab, Tofacitinib, and Ustekinumab for Moderately to Severely Active Ulcerative ColitisClinical Research Published on 2024-01-222024-09-04 Journal: Inflammatory bowel diseases [Category] 대상포진, [키워드] filgotinib MAIC ulcerative colitis [DOI] 10.1093/ibd/izad037 PMC 바로가기 [Article Type] Clinical Research
Withdrawal and Re-treatment with Filgotinib in Ulcerative Colitis: Post Hoc Analyses of the Phase 2b/3 SELECTION and SELECTIONLTE StudiesOriginal Article Published on 2024-01-042024-09-05 Journal: Journal of Crohn's and Colitis [Category] update2024, [키워드] filgotinib re-treatment ulcerative colitis [DOI] 10.1093/ecco-jcc/jjad123 PMC 바로가기 [Article Type] Original Article
Safety and efficacy of filgotinib, lanraplenib and tirabrutinib in Sjögren’s syndrome: a randomized, phase 2, double-blind, placebo-controlled studyClinical Science Published on 2022-12-042024-09-04 Journal: Rheumatology (Oxford, England) [Category] 대상포진, [키워드] Efficacy filgotinib lanraplenib randomized trial Safety Sjögren's syndrome tirabrutinib [DOI] 10.1093/rheumatology/keac167 PMC 바로가기 [Article Type] Clinical Science
Are Janus kinase inhibitors safe and effective in treating the key clinical domains of psoriatic arthritis? A systematic review and meta‐analysisReviews Published on 2022-10-022024-09-04 Journal: International journal of rheumatic diseases [Category] 대상포진, [키워드] dactylitis Enthesitis filgotinib Janus kinase inhibitors psoriasis psoriatic arthritis Tofacitinib Upadacitinib [DOI] 10.1111/1756-185X.14447 PMC 바로가기 [Article Type] Reviews
Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequencesEchinacea purpurea (L.) 단핵구의 Moench 처리는 강장제 인터페론 신호 전달, 선천 면역 유전자 발현 증가 및 내인성 레트로 바이러스 서열의 DNA 반복 과메틸화 침묵을 촉진합니다Research Article Published on 2021-05-122022-09-10 Journal: BMC Complementary Medicine and Therapies [Category] SARS, 유전자 메커니즘, 치료제, [키워드] Activation Analysis Antiviral change changes in characterisation chemokine chemotaxis common cold conserved CoV CpG Defense DNA DNA methylation Duration of infection Echinacea element epigenome experiment expression filgotinib Gene Expression genomic Herbal HERV HERVs IFN IFN signaling immunomodulation immunomodulatory effect induce inhibitor innate immune Innate immunity interferon interferon signaling involved janus Janus kinase kinase LTR monocyte Monocytes nuclear DNA Pathways Pattern recognition Pattern recognition receptors pharmacological promise promote Protective reduce Regulation respiratory Respiratory tract infections Result retroviral SARS-CoV-2 sequence Severe acute respiratory syndrome Signaling strain supplementary material Symptom Systems biology THP1 monocytes Transcription Transcriptome Treatment Trigger triggers Viral viral infections virus viruses [DOI] 10.1186/s12906-021-03310-5 PMC 바로가기 [Article Type] Research Article
Early phase studies of JAK1 selective inhibitors in rheumatoid arthritisSupplement Published on 2021-05-052024-09-04 Journal: Rheumatology (Oxford, England) [Category] 대상포진, [키워드] filgotinib itacitinib Janus kinase inhibitors rheumatoid arthritis Treatment Upadacitinib [DOI] 10.1093/rheumatology/keaa893 PMC 바로가기 [Article Type] Supplement
Clinical use of Jak 1 inhibitors for rheumatoid arthritisSupplement Papers Published on 2021-05-052024-09-04 Journal: Rheumatology (Oxford, England) [Category] 대상포진, [키워드] Efficacy filgotinib Jak 1 selectivity Safety Upadacitinib [DOI] 10.1093/rheumatology/keab265 PMC 바로가기 [Article Type] Supplement Papers
Effect of janus kinase inhibitors and methotrexate combination on malignancy in patients with rheumatoid arthritis: a systematic review and meta-analysis of randomized controlled trialsReview Published on 2021-04-282024-09-02 Journal: Autoimmunity Highlights [Category] 대상포진, [키워드] Baricitinib Decernotinib filgotinib jak inhibitors methotrexate Peficitinib rheumatoid arthritis Tofacitinib Upadacitinib [DOI] 10.1186/s13317-021-00153-5 PMC 바로가기 [Article Type] Review
Emerging oral targeted therapies in inflammatory bowel diseases: opportunities and challengesReviews Published on 2017-09-052024-09-04 Journal: Therapeutic Advances in Gastroenterology [Category] 대상포진, [키워드] AJM300 filgotinib fingolimod inflammatory bowel diseases mongersen oral therapy Ozanimod Phosphatidylcholine Tofacitinib [DOI] 10.1177/1756283X17727388 PMC 바로가기 [Article Type] Reviews