Deep learning-based cell segmentation for rapid optical cytopathology of thyroid cancerArticle Published on 2024-07-162024-09-05 Journal: Scientific Reports [Category] update2024, [키워드] Applied optics Automated cell segmentation cytopathology Fluorescence polarization Methylene blue Optical imaging Semantic segmentation thyroid cancer [DOI] 10.1038/s41598-024-64855-2 PMC 바로가기 [Article Type] Article
Manidipine is not a potential inhibitor against SARS-CoV-2 main proteaseAntiviral Agents Published on 2024-03-312024-09-05 Journal: Med Instrum [Category] update2024, [키워드] COVID-19 Fluorescence polarization Main protease inhibitor manidipine SARS-CoV-2 [DOI] 10.1128/aac.01297-23 PMC 바로가기 [Article Type] Antiviral Agents
DNA Probes for Cas12a-Based Assay with Fluorescence Anisotropy Enhanced Due to Anchors and SaltsArticle Published on 2023-12-162024-09-05 Journal: Biosensors [Category] update2024, [키워드] CRISPR/Cas12 DNA trans-target Fluorescence polarization G-quadruplex hairpin probe ssDNA probe trans-cleavage [DOI] 10.3390/bios13121034 PMC 바로가기 [Article Type] Article
A robust high-throughput fluorescence polarization assay for rapid screening of SARS-CoV-2 papain-like protease inhibitorsSARS-CoV-2 파파인 유사 프로테아제 억제제의 신속한 스크리닝을 위한 강력한 고처리량 형광 편광 분석Article Published on 2022-09-012022-09-11 Journal: Virology [Category] COVID19(2023년), SARS, 치료제, [키워드] Anacardic acid antiviral agent Antiviral agents cleavage competitive inhibitor COVID-19 develop disease effective therapy Fluorescence Fluorescence polarization functional High-throughput screening immune evasion in vitro inhibitor inhibitors lifecycle Papain Papain-like protease Papain-like protease inhibitors pathogen PLPro polyprotein protease protease inhibitors public health responsible robust SARS-CoV-2 Vaccines [DOI] 10.1016/j.virol.2022.07.006 PMC 바로가기 [Article Type] Article
Identification of potent inhibitors of arenavirus and SARS-CoV-2 exoribonucleases by fluorescence polarization assayArticle Published on 2022-08-012023-07-09 Journal: Antiviral Research [Category] COVID19(2023년), [키워드] Arenaviridae Cellular assays Coronaviridae Exoribonuclease activity Fluorescence polarization IC(50) inhibitors Phosphohydrolase activity Screening [DOI] 10.1016/j.antiviral.2022.105364 PMC 바로가기
[Identifying SARS-CoV-2 main protease inhibitors by a novel sandwich-like fluorescence polarization screening assay]Article Published on 2022-06-252023-07-09 Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology [Category] COVID19(2023년), [키워드] Anacardic acid Fluorescence polarization High-throughput screening Main protease inhibitor pentagalloylglucose. SARS-CoV-2 [DOI] 10.13345/j.cjb.210949
Development of a simple and miniaturized sandwich-like fluorescence polarization assay for rapid screening of SARS-CoV-2 main protease inhibitorsMethodology Published on 2021-12-052022-11-01 Journal: Cell & Bioscience [Category] COVID-19, [키워드] 3CL protease inhibitor acute respiratory syndrome Analysis antiviral agent approved BAS catalytic site caused Chinese traditional medicine conserved coronavirus coronavirus disease COVID-19 COVID-19 patients develop development Dieckol docking Ecklonia cava enzyme evaluated exhibited Fluorescence polarization genomic RNA high affinity High-throughput screening highest identify in viral in vitro inhibitor Interaction Main protease inhibitor MPro pandemic polyprotein predicted protease Proteases Replication Result SARS-CoV-2 SARS-CoV-2 main protease SARS-CoV-2 Mpro selective SPR Spread therapeutic agent therapeutic target Treatment [DOI] 10.1186/s13578-021-00720-3 PMC 바로가기 [Article Type] Methodology
Fluorescence polarization system for rapid COVID-19 diagnosisArticle Published on 2021-04-152023-06-19 Journal: Biosensors & bioelectronics [Category] MERS, SARS, [키워드] biosensor COVID-19 CRISPR/Cas Fluorescence polarization isothermal amplification point-of-care [DOI] 10.1016/j.bios.2021.113049 PMC 바로가기
An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screenArticle Published on 2020-08-042023-06-08 Journal: Proceedings of the National Academy of Sciences of [Category] Fulltext, 신종인플루엔자, [키워드] Fluorescence polarization hemagglutinin inhibitor High-throughput screening Influenza virus X-ray crystallography [DOI] 10.1073/pnas.2006893117 PMC 바로가기