Association of vitamin B12, folate, and homocysteine with COVID-19 severity and mortality: A systematic review and meta-analysisSystematic Review Published on 2024-05-202024-09-05 Journal: SAGE Open Medicine [Category] update2024, [키워드] COVID-19 folate homocysteine Mortality severity vitamin B12 [DOI] 10.1177/20503121241253957 PMC 바로가기 [Article Type] Systematic Review
Climate Stressors and Physiological Dysregulations: Mechanistic Connections to PathologiesReview Published on 2023-12-232024-09-05 Journal: International Journal of Environmental Research an [Category] update2024, [키워드] Autoimmune disease chaperones folate metabolites Mitochondria oxidative stress [DOI] 10.3390/ijerph21010028 PMC 바로가기 [Article Type] Review
Correlates of Iron, Cobalamin, Folate, and Vitamin A Status among Stunted Children: A Cross-Sectional Study in UgandaArticle Published on 2023-08-022024-08-28 Journal: Nutrients [Category] 말라리아, [키워드] cobalamin folate iron micronutrient status stunting vitamin A
Repurposing benzbromarone as antifolate to develop novel antifungal therapy for Candida albicans벤즈브로마론을 항엽산으로 용도 변경하여 칸디다 알비칸스에 대한 새로운 항진균 요법 개발Article Published on 2022-06-182022-09-11 Journal: Journal of molecular modeling [Category] 신약개발, [키워드] Absorption Antifungal antifungal therapy approach Benzbromarone Biosynthesis Candida Candida albican Candida albicans candidiasis coenzyme complex complications Computational drug COVID-19 COVID-19 patient COVID-19 patients develop DHFR dihydrofolate drug resistance Effect enzyme folate Folic acid followed by fungal Fungal infection fungal infections Human identify Immunocompromised Infection inhibitor involved macromolecular Mild molecular molecular docking Mortality nucleotides Probability problem problems repurposing required responsible resulting Severe infection severe infections symptomatic systemic effect systemic effects tetrahydrofolate therapy toxic effects Treatment Virtual screening White-fungus. [DOI] 10.1007/s00894-022-05185-w PMC 바로가기 [Article Type] Article
COVID-19 and One-Carbon MetabolismReview Published on 2022-04-102023-07-08 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), [키워드] choline cysteine folate glutathione homocysteine methionine methionine sulfoxide purine biosynthesis. S-adenosylhomocysteine S-adenosylmethionine [DOI] 10.3390/ijms23084181 PMC 바로가기 [Article Type] Review
The Role of Methyl Donors of the Methionine Cycle in Gastrointestinal Infection and InflammationReview Published on 2021-12-292023-08-30 Journal: International journal for equity in health [Category] E형 간염, [키워드] folate Inflammation methionine Methylation S-adenosyl methionine vitamin B12 [DOI] 10.3390/healthcare10010061 PMC 바로가기 [Article Type] Review
Impaired Folate-Mediated One-Carbon Metabolism in Type 2 Diabetes, Late-Onset Alzheimer’s Disease and Long COVID제2형 당뇨병, 후기 발병 알츠하이머병 및 장기 코로나에서 엽산 매개 단일 탄소 대사 장애Review Published on 2021-12-232022-09-10 Journal: Medicina [Category] SARS, 유전자 메커니즘, [키워드] Abnormalities Alzheimer’s disease Alzheimer’s disease biochemical Biomarker biosynthetic biosynthetic pathways carbon clinical disease COVID COVID-19 cytoplasm developmental diabetes Diabetes Mellitus Diseases elevated epigenetics folate functional homocysteine hyperhomocysteinemia Impaired incorporation knowledge Long Long COVID mechanism metabolic network metabolic pathway metabolic pathways metabolism Mitochondria MTHFR gene mutations nucleus nutritional B vitamin deficiencies PASC pathology pathway progression Repurposed drugs responsible SARS-CoV-2 Stress the reader Therapeutics Treatment Type type 2 diabete Type 2 diabetes mellitus Vitamin vitamins [DOI] 10.3390/medicina58010016 PMC 바로가기 [Article Type] Review
Nutritional risk factors for SARS-CoV-2 infection: a prospective study within the NutriNet-Santé cohortSARS-COV-2 감염에 대한 영양 위험 요인 : Nutrinet-Santé 코호트 내의 전향 적 연구Research Article Published on 2021-11-302022-09-10 Journal: BMC Medicine [Category] MERS, SARS, 치료기술, [키워드] Analysis anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody association calcium Cohort cohort study conducted contribute COVID-19 COVID-19 pandemic diet dietary intake Dietary intakes Dried blood spots ELISA Evidence Factor fiber folate food group food groups France French fruit immune system Infectious disease Infectious diseases logistic regression model non-communicable diseases positive Prevent Probability Prospective Study repeated Result risk risk factor SARS-CoV-2 SARS-COV-2 infection Seroprevalence supplementary material susceptibility Vitamin C vitamin K vitamins women [DOI] 10.1186/s12916-021-02168-1 PMC 바로가기 [Article Type] Research Article
The association between micronutrient and hemogram values and prognostic factors in COVID-19 patients: A single-center experience from TurkeyObservational Study Published on 2021-06-012022-10-05 Journal: International journal of clinical practice [Category] SARS, 임상, [키워드] addition advanced age age Anemia anti-inflammatory effect antioxidant effect approach association Chronic diseases city comorbid disease Complete Concentration correlated COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients dead patients deficiencies demonstrated diagnosed with COVID-19 died disease evaluated examined excessive use folate Follow-up Gender hemoglobin hospital Hospital stay Hospitalization hypertension ICU ICU admission immune system immunomodulatory intensive care unit Intubated iron Leukocytosis lymphocyte lymphocyte counts male material men Micronutrient micronutrients multivitamin supplementation parameter Patient poor prognosis Prognostic factor Prognostic factors protective role provided respiratory tract infection retrospective significantly higher single-center the disease the mean the patient Turkey vitamin B12 vitamin D deficiency vitamin D level White blood cell worse prognosis [DOI] 10.1111/ijcp.14078 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replicationSARS-CoV-2는 바이러스 복제를 위해 엽산과 단일 탄소 대사를 납치합니다.Article Published on 2021-03-152022-09-10 Journal: Nature Communications [Category] SARS, 유전자 메커니즘, 치료제, [키워드] acute respiratory syndrome coronavirus Alter Analysis bypassing carbon carbon metabolism cell growth cellular metabolism coronavirus coronavirus 2 COVID-19 pandemic de novo Effect folate Glucose growth Host host cell infected cells inhibitor inhibitors Intracellular lifecycle metabolism metabolomic metabolomics methotrexate novel beta-coronavirus Outbreaks performed post-transcriptional level purine Replication respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected cells severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Support survival targeted therapy transcriptional translation Viral viral genome viral replication Viral RNA virus Virus-host interactions viruses [DOI] 10.1038/s41467-021-21903-z PMC 바로가기 [Article Type] Article