A six-month study of anti-SARS-CoV-2 BNT162b2 mRNA vaccination: A comparative analysis of essential trace elements and anti-RBD IgG sera levelsArticle Published on 2022-12-012022-11-15 Journal: Journal of trace elements in medicine and biology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] (Post)vaccinal immunity adaptive Analysis analyzed Anti-RBD IgG anti-SARS-CoV-2 anti-SARS-CoV-2 IgG Antibody detection Antibody titers association biochemical BNT162b2 mRNA BNT162b2 mRNA vaccine changes in Concentration Cu Effect elevated Essential Essential trace elements expressed female follow-up period glycoprotein healthy HEK-293 human serum IgG antibody Immunity immunization investigated mRNA vaccine not affected observation period produced producing Protein purified RBD Receptor binding domain remained SARS-CoV-2 sera serum specific IgG antibody spike T cells Total Trace element vaccination Vaccine Volunteer women Zn [DOI] 10.1016/j.jtemb.2022.127079 PMC 바로가기
Reactive synovitis of the knee joint after COVID-19 vaccination: The first ultrastructural analysis of synovial fluidArticle Published on 2022-11-012022-11-15 Journal: International journal of rheumatic diseases [Category] SARS, 치료기술, [키워드] acute respiratory syndrome Administered adverse event affected Analysis Arthritis blood test clinical examination complex Consequences coronavirus coronavirus 2019 disease COVID-19 COVID-19 vaccination COVID-19 vaccine cytological-energy analysis detect Dexamethasone Diseases dose examined excluded Fever first dose follow-up period full recovery Infection intravenously joint Messenger RNA outcome Patient polymerase chain reactive Reactive arthritis recorded resulting reverse transcription SARS-CoV-2 Side-effects Spread Symptom synovial fluid therapy Treatment Ultrastructural analysis Vaccine Vaccines virus with COVID-19 [DOI] 10.1111/1756-185X.14411 PMC 바로가기
Six-month humoral and cellular immune response to the third dose of BNT162b2 anti-SARS-CoV-2 vaccine in patients with solid tumors: a longitudinal cohort study with a focus on the variants of concernArticle Published on 2022-10-012022-11-15 Journal: ESMO open [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] anti-SARS-CoV-2 Anti-spike antibody BNT162b2 BNT162b2 anti-SARS-CoV-2 vaccine BNT162b2 vaccine booster Cancer cancer patient cell-mediated immune Cellular immune response Concentration COVID-19 delta variant dose evaluated follow-up period highest highlight Hospitalization humoral Immunoglobulin Infection interferon-γ interquartile range longitudinal cohort study lowest median Messenger RNA Neutralizing Neutralizing activity neutralizing antibody of BNT162b2 omicron Oxygen therapy Patient positive response reduced reduction in required SARS-CoV-2 serum Seven solid tumor subject the SARS-CoV-2 third dose Treatment triggering Vaccine variant variants of concern VOCs were measured were used whole blood sample wild-type strain [DOI] 10.1016/j.esmoop.2022.100574 PMC 바로가기
Evaluation of the efficacy of oral nano-silymarin formulation in hospitalized patients with COVID-19: A double-blind placebo-controlled clinical trialArticle Published on 2022-10-012022-11-15 Journal: Phytotherapy research : PTR [Category] COVID19(2023년), SARS, 치료제, [키워드] alanine aminotransferase Anti-viral Antiviral assigned baseline clinical trial Concomitant COVID-19 cytokine release Cytokine release syndrome Dexamethasone dosage double-blind Effect effective Effectiveness Efficacy Evidence follow-up period gel Hospitalization hospitalized patient Laboratory Laboratory parameters lack liver enzyme management outbreak pandemic participant Patient patients with COVID-19 placebo group placebo-controlled clinical trial receiving Remdesivir sample sizes SARS-CoV-2 significant difference significantly silymarin Symptom the placebo group therapeutic strategy Treatment treatment group two group viral disease were assessed [DOI] 10.1002/ptr.7537 PMC 바로가기
Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patientsArticle Published on 2022-10-012022-11-16 Journal: The lancet. Psychiatry [Category] COVID19(2023년), SARS, 변종, [키워드] 1:1 Adults Affect age Alpha Analysis Anxiety Anxiety Disorder B.1.1.529 B.1.1.7 B.1.617.2 baseline Brain Bulgaria children cognitive Cohort cohort of patient cohorts cohorts of patient collected COVID-19 death rate Dementia Demographic factors diagnose diagnosed diagnosed with COVID-19 Diagnosis diagnosis of COVID-19 died disorder disorders Electronic health record epilepsy female Follow-up follow-up period foundation greater hazard ratio health-care health-care system help higher risk hospital HRs incidence increased risk India indicate individual Insomnia International ischaemic stroke less Malaysia male matching neurological Older other respiratory infections outcome outcomes Oxford Parkinsonism Pathogenesis Patient primary care profile proportion Psychiatric psychiatric diagnose psychiatric diagnosis psychiatric disorder reached recorded remained representing respiratory infection response retrospective cohort retrospective cohort study returned risk risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant Seizure Seizures severe COVID-19 illness significantly Spain stratified study period sustained Taiwan trajectory USA vaccination variant variants was done while with COVID-19 Wolfson [DOI] 10.1016/S2215-0366(22)00260-7 PMC 바로가기
Household transmission of the SARS-CoV-2 Omicron variant in DenmarkArticle Published on 2022-09-232022-11-16 Journal: Nature Communications [Category] SARS, 변종, [키워드] Contact Delta delta variant Denmark dominant driven by follow-up period household immune immune evasion increase in inherent odds of infection omicron SARS-CoV-2 transmission SARS-CoV-2 variant secondary attack rate Secondary infection the SARS-CoV-2 Transmissibility Transmission variant VoC [DOI] 10.1038/s41467-022-33328-3 PMC 바로가기
SARS-CoV-2 specific T cell and humoral immune responses upon vaccination with BNT162b2: a 9 months longitudinal studyArticle Published on 2022-09-142022-11-15 Journal: Scientific Reports [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome BNT162b2 vaccine booster dose Cellular immune response changes in conducted coronavirus coronavirus disease COVID-19 demonstrated dose first vaccination follow-up period highest hospital humoral humoral immune response IgG IgG antibody immune response neutralization Neutralizing activity neutralizing antibody no correlation performed receiving SARS-CoV-2 SARS-CoV-2 neutralizing antibodies SARS-CoV-2 spike second vaccination serological Seven significantly sustained T cell T cell assay T cell response T cell responses the vaccine vaccination [DOI] 10.1038/s41598-022-19581-y PMC 바로가기
Efficacy, immunogenicity and safety of COVID-19 vaccines in older adults: a systematic review and meta-analysisArticle Published on 2022-09-132022-11-15 Journal: Frontiers in Immunology [Category] 변종, 진단, [키워드] 95% confidence interval Adults adverse event AEs analyzed booster caused Cochrane Library control group control groups Controlled trial coronavirus disease Coverage COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines DNA vaccines dose Efficacy eligible Factor Factors Fever follow-up period geometric mean titer GMT Health highest immunogenicity inactivated incidence Increased Local Meta-analysis meta-regression analysis mRNA vaccine Neutralizing antibodies Older older adult Older adults outcome Pain provided random-effect Randomized controlled trial randomized controlled trials (RCTs) Registered required Research risk Safety searched seroconversion rate severe disease significantly increased SMD standardized mean difference Strains Surveillance susceptible systematic review systemic AEs Universal vaccination Vaccine variant Web of Science [DOI] 10.3389/fimmu.2022.965971 PMC 바로가기
Effectiveness and adherence to closed face shields in the prevention of COVID-19 transmission: a non-inferiority randomized controlled trial in a middle-income setting (COVPROSHIELD)COVID-19 전염 예방에 대한 폐쇄형 안면 보호구의 효과 및 준수: 중간 소득 환경에서의 비열등 무작위 대조 시험(COVPROSHIELD)Randomized Controlled Trial Published on 2022-08-202022-09-11 Journal: Trials [Category] SARS, 임상, 치료기술, [키워드] 95% CI active control group Antibody test assigned benefit Chain Reaction clinical clinical trial Closed face shield combined use Community condition COVID-19 COVID-19 pandemic cross crowding determine disease Effectiveness face Face mask Face masks Face shield Follow-up follow-up period groups highly active IgM antibody inferiority intention-to-treat analysis intervention group limit Mask Masks mitigate non-inferiority Open-label participant per-protocol analysis polymerase chain polymerase chain reaction positive Prevent prevention of COVID-19 Primary outcome Randomized Randomized controlled trial Randomly reverse transcription risk risk difference SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV-2 test SARS-CoV-2 transmission setting Spread surgical test result two groups Ventilation Viral transmission [DOI] 10.1186/s13063-022-06606-0 PMC 바로가기 [Article Type] Randomized Controlled Trial
Inactivated vaccines prevent severe COVID-19 in patients infected with the Delta variant: A comparative study of the Delta and Alpha variants from China비활성화된 백신은 Delta 변이에 감염된 환자에서 심각한 COVID-19를 예방합니다: 중국의 Delta 및 Alpha 변이에 대한 비교 연구Article Published on 2022-08-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] addition Alpha variant Antibiotics China Clinical characteristics clinical manifestation clinical manifestations Delta delta variant diagnosed disease dose Efficacy follow-up period generally mild glucocorticoid Glucocorticoids Hospital stay Hospitalization hospitalized patient Inactivated vaccine Inactivated Vaccines Infection information majority Mild MOST outcome Patient Prevent proportion replaced SARS-CoV-2 SARS-COV-2 infection severe COVID-19 vaccination Vaccine widespread Zhejiang [DOI] 10.1002/jmv.27759 PMC 바로가기 [Article Type] Article