Plasma Proteomics of COVID-19–Associated Cardiovascular Complications: Implications for Pathophysiology and TherapeuticsResearch article Published on 2022-05-012022-10-05 Journal: JACC: Basic to Translational Science [Category] 바이오마커, 유전자 메커니즘, [키워드] ADAMTS13 cardiovascular cardiovascular complication Case-control cause Cohort COVID-19 COVID-19 patient COVID-19 patients disease severity dominant driving finding FSTL3 identify Implications Injury loss-of-function marker mechanism Microvascular thrombosis Myocardial myocardial injury pathophysiology performed phenotype plasma proteomics protease Protein proteomics senescence Signaling Stress therapeutic Therapeutics [DOI] 10.1016/j.jacbts.2022.01.013 [Article Type] Research article
The Activin/FLRG Pathway Associates with Poor COVID-19 Outcomes in Hospitalized PatientsActivin/FLRG Pathway는 입원 환자의 COVID-19 결과가 좋지 않습니다.Clinical Trial Published on 2021-11-012022-09-10 Journal: Molecular and Cellular Biology [Category] MERS, SARS, 비임상, 임상, 진단, [키워드] activate activin activin A activin B acute respiratory disease acute respiratory disease syndrome all-cause mortality antibody ARDS Associate blockade breath characterized Comorbidities COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokine storm Cytokines decrease demonstrated develop elevated evaluate Evidence examined FLRG FSTL3 Hospital admission hospitalized COVID-19 patients increase in indicate indicated induce inhibitor lung viral load mechanical ventilation NF-κB NF-κB pathway outcome pathology Poor risk SARS-CoV-2 SARS-COV-2 infection Signaling subset syndrome the disease those with comorbidities treating COVID-19 patient Viral Viral load [DOI] 10.1128/MCB.00467-21 PMC 바로가기 [Article Type] Clinical Trial