Amantadine for Traumatic Brain Injury—Supporting Evidence and Mode of ActionReview Published on 2024-07-132024-09-05 Journal: Biomedicines [Category] update2024, [키워드] amantadine aromatic amino acids decarboxylase clinical GDNF in vitro in vivo mechanism of action NMDA receptors Preclinical sigma-1 Traumatic brain injury [DOI] 10.3390/biomedicines12071558 PMC 바로가기 [Article Type] Review
Association of extracellular vesicle inflammatory proteins and mortality세포외 소포 염증 단백질과 사망률의 연관성Article Published on 2022-08-182022-09-11 Journal: Scientific Reports [Category] 바이오마커, [키워드] age Biomarker CCL23 CDCP1 circulating Cohort Concentration COVID-19 pandemic CSF-1 CXCL9 Deceased Decline died disease DNA Ethnic groups EVs Extracellular Extracellular vesicles functional GDNF identify increased mortality individual inflammatory protein inflammatory proteins intercellular Life expectancy lipids marker MCP-1 mitochondrial mitochondrial DNA Mortality no significant difference no significant differences nucleic acids plasma Potential biomarker potential biomarkers Proteins Racial risk Sex significantly STAMBP the United State United States Vesicle [DOI] 10.1038/s41598-022-17944-z PMC 바로가기 [Article Type] Article
Advantages of visualisations to evaluate and communicate adverse event information in randomised controlled trials무작위 대조 시험에서 이상 반응 정보를 평가하고 전달하기 위한 시각화의 장점Research Published on 2020-12-222022-09-10 Journal: Trials [Category] 임상, 치료제, [키워드] adverse event adverse events Adverse reactions AEs Analysis article asymmetry collected communication comparison complex construction Controlled trial controlled trials COVID-19 Data analysis effective evaluate event extreme Frequency GDNF Graphics Guidance harms implementation in some information investigator investigators lack less offer outcome Parkinson disease Parkinson’s disease Placebo-controlled trials point estimate point estimates profile Prominent provided randomised controlled trial Randomised controlled trials RCTs Remdesivir Reporting risk shown Stata statistical supplementary material Support treatment effect treatment effects Trial trials Visual Visualisation volcano plot Volume [DOI] 10.1186/s13063-020-04903-0 PMC 바로가기 [Article Type] Research
Suppressor of cytokine signaling 2 modulates the immune response profile and development of experimental cerebral malariaarticle Published on 2016-05-312024-09-01 Journal: Brain, Behavior, and Immunity [Category] 말라리아, [키워드] BDNF cerebral malaria GDNF immune regulation l-NAME Neuroimmune response Neuroinflammation neurotrophic factors nitric oxide SOCS2 [Article Type] article