An Age-Specific Crisis Awareness Survey of COVID-19 Vaccines and Treatments Among Healthy Japanese AdultsInfectious Disease Published on 2024-07-272024-09-05 Journal: Cureus [Category] update2024, [키워드] age Awareness COVID-19 Generation pandemic [DOI] 10.7759/cureus.65549 PMC 바로가기 [Article Type] Infectious Disease
The Binding of the SARS-CoV-2 Spike Protein to Platelet Factor 4: A Proposed Mechanism for the Generation of Pathogenic AntibodiesArticle Published on 2024-02-202024-09-05 Journal: Biomolecules [Category] update2024, [키워드] Generation mechanism PF4 PF4/SP antibodies SARS-CoV-2 spike protein [DOI] 10.3390/biom14030245 PMC 바로가기 [Article Type] Article
Artificial Cell Membrane Polymersome-Based Intranasal Beta Spike Formulation as a Second Generation Covid-19 VaccineArticle Published on 2022-10-252022-11-15 Journal: ACS Nano [Category] COVID19(2023년), SARS, 변종, 비임상, 진단, [키워드] ACM acute respiratory syndrome adverse effect airway antibodies antibody antigen presenting cells artificial Beta Beta spike C57BL/6 cell membrane clinical symptom clinical trial component conditions coronavirus coronavirus disease COVID-19 CpG cross-neutralizing current delivery of cargo dendritic cells dose doses evaluate evaluated Formulation generate Generation Good hamster hamsters immune responses immunization immunogenic induce Infection initiated interval intranasal mice neutralize neutralizing antibody neutralizing responses New omicron Phase 1 polymersome Practice PROTECT reduction repeated Safety SARS-CoV-2 second serum IgG spike Spike protein Spike-based vaccine Support Toxicity upper respiratory tract Vaccine variants viral clearance Viral load virus weight loss wild type [DOI] 10.1021/acsnano.2c06350 PMC 바로가기
Nucleocapsid and spike antibody responses following virologically confirmed SARS-CoV-2 infection: an observational analysis in the Virus Watch community cohortArticle Published on 2022-10-012022-11-15 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] affected age Analysis Anti-N anti-S antibody Antibody Response capillary blood categories Cohort cohort study Community Corona Corona virus COVID-19 COVID-19 infection cumulative eligible England enrolled Evidence female Generation incidence individual Infection nucleocapsid participant past medical history PCR PCR-confirmed peaked polymerase chain positive Primary outcome provided SARS-CoV-2 SARS-COV-2 infection second sensitivity Seroprevalence Serosurveillance Sex Swab System tested vaccination variable [DOI] 10.1016/j.ijid.2022.07.053 PMC 바로가기
Toward Next Generation Lateral Flow Assays: Integration of NanomaterialsArticle Published on 2022-09-282022-11-15 Journal: Chemical reviews [Category] Fulltext, MERS, 진단, [키워드] Bacterial complex COVID-19 diagnostic diagnostics feasibility Flow Generation highlight inherent integration Lateral limitation limits Nanomaterial pesticide platform point-of-care pregnancy test quantification receptor review sensitivity [DOI] 10.1021/acs.chemrev.1c01012 PMC 바로가기
Aerosol Generation During Otologic SurgeryObservational Study Published on 2022-09-012022-10-05 Journal: Otology & neurotology : official publication of th [Category] COVID19(2023년), SARS, 임상, [키워드] acute respiratory syndrome aerosol Aerosol generation aerosol-generating procedures average Concentration concentrations coronavirus cough coughing ENhance Factor Generation help identify measure occur Operating room Otologic outcome Particle pathogen Pathogens Prospective Study quantified recorded reduce reduced required significantly higher Spread suction surgery to define Total was measured were recorded were used [DOI] 10.1097/MAO.0000000000003591 PMC 바로가기 [Article Type] Observational Study
Development of a pentavalent broadly protective nucleoside-modified mRNA vaccine against influenza B viruses Research Published on 2022-08-092022-10-05 Journal: Nature Communications [Category] 유전자 메커니즘, 치료제, [키워드] Antigen antigenic conserved cross-reactive immune response development effective elicit evaluate expressing Generation influenza B Influenza virus lineages long-lasting low dose messenger mice morbidity morbidity and mortality mRNA nucleoside-modified mRNA pentavalent platform PROTECT Protective reducing RNA single vaccination Support tested Vaccine vaccine candidate vaccine candidates vaccine platform virus [DOI] 10.1038/s41467-022-32149-8 [Article Type] Research
Generation and characterization of humanized synergistic neutralizing antibodies against SARS-CoV-2SARS-CoV-2에 대한 인간화 시너지 중화 항체의 생성 및 특성화Article Published on 2022-08-012022-09-12 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome antibody binding chimeric clinical therapy Combination coronavirus coronavirus disease COVID-19 epitope exhibited Generation global public health humanized humanized antibodies humanized neutralizing antibody Local neutralization activity Neutralizing Neutralizing activity neutralizing antibody Protein pseudovirus pseudovirus system RBD recognize SARS-CoV-2 SARS-CoV-2 pseudovirus single-chain antibody synergistic synergistic neutralizing activity. the receptor-binding domain the SARS-CoV-2 [DOI] 10.1002/jmv.27801 PMC 바로가기 [Article Type] Article
Gestational SARS-CoV-2 infection is associated with placental expression of immune and trophoblast genes임신성 SARS-CoV-2 감염은 면역 및 영양막 유전자의 태반 발현과 관련이 있습니다Article Published on 2022-08-012022-09-11 Journal: Placenta [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] absence age Analysis antibody Birth CGB3 change contribute correlation CXCL10 DDX58 decreased expression during pregnancy Effect evaluate expression feature Features fetus Fisher Gene Expression Generation gestational age group groups Health histologic Histopathology IgG IgG antibody immune immune gene immune genes increased expression Infant Infants Linear regression linear regression models Maternal median molecular Mount Sinai Mount Sinai Health System NanoString nasal swab New York City no significant differences not differ offspring outcome participant Participants performed Placenta placental Placentas positive positive RT-PCR Pregnancy pregnant prospective cohort study PSG3 SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV-2 IgG antibody SARS-COV-2 infection serology test severe disease significant difference significant differences Spearman statistical analyses System term the SARS-CoV-2 TLR3 Transmission vertical transmission [DOI] 10.1016/j.placenta.2022.06.017 PMC 바로가기 [Article Type] Article
A Comparison of Bioinformatics Pipelines for Enrichment Illumina Next Generation Sequencing Systems in Detecting SARS-CoV-2 Virus StrainsSARS-CoV-2 바이러스 균주 검출 시 Illumina 차세대 시퀀싱 시스템 강화를 위한 생물정보학 파이프라인 비교Comparative Study Published on 2022-07-262022-09-11 Journal: Genes [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Algorithm Amino acid bioinformatics bioinformatics pipeline capture method characterization coronavirus 2 coronavirus disease Coronavirus disease 2019 Coverage COVID-19 Critical Deletion downstream enrichment enrichment. full-length SARS-CoV-2 genome Generation Hope Human genome Illumina Indonesia insertion limitation Major mapped mapping metagenomic mutations next generation sequencing NGS normal nucleotide nucleotide substitution nucleotide substitutions pandemic Panel Previous studies previous study reads respiratory respiratory virus respiratory viruses SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 strain SARS-CoV-2 strains sequence Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus situation SNPs strain Strains System table the SARS-CoV-2 genome utilization Variation virus worldwide pandemic worsening [DOI] 10.3390/genes13081330 PMC 바로가기 [Article Type] Comparative Study