Pathogenesis and Host Immune Response in LeprosyArticle Published on 2021-12-312024-09-08 Journal: Adv Exp Med Biol [Category] 한센병, [키워드] foamy macrophages giant cells granuloma lepromatous leprosy Mycobacterium laprae Schwann cells Tuberculoid leprosy PMC 바로가기
Essential gene deletions producing gigantic bacteria거대 박테리아를 생성하는 필수 유전자 결실Research Article Published on 2019-06-102022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accelerated Acinetobacter Analysis antibiotic Antibiotics Bacteria Bacterial Bacterial infections blocked Cell cell wall cell wall synthesis cells cleave consequence conserved creating dead dead cell dead cells deleted Deletion eliminating enzyme Essential feature function functions Genetic Giant giant cell giant cells help hydrolysis identify inactivated independent life lysed lytic transglycosylase mutant mutants Mutation natural transformation osmotic overcome overlapping pathogenic pathway peptide peptidoglycan polymerization precursor predicted produced producing required respond responsible resulting sacculus targets the cell the dead Tn-seq transposon Treatment [DOI] 10.1371/journal.pgen.1008195 PMC 바로가기 [Article Type] Research Article