Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer’s diseaseResearch Article Published on 2024-06-212024-09-05 Journal: Alzheimer's & dementia : the journal of the Alzhei [Category] update2024, [키워드] Alzheimer's disease Biomarkers glial cells nonhuman primates Tau [DOI] 10.1002/alz.13868 PMC 바로가기 [Article Type] Research Article
Neuropathological findings in Down syndrome, Alzheimer’s disease and control patients with and without SARS-COV-2: preliminary findingsOriginal Paper Published on 2024-05-272024-09-05 Journal: Acta Neuropathologica [Category] update2024, [키워드] Alzheimer’s disease Brain Corona viruses COVID-19 Down syndrome glial cells neurologic symptoms SARS-CoV-2 [DOI] 10.1007/s00401-024-02743-9 PMC 바로가기 [Article Type] Original Paper
COVID-19 causes neuronal degeneration and reduces neurogenesis in human hippocampusArticle Published on 2022-12-012022-11-16 Journal: Apoptosis [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Alter Analysis Apoptosis assist Brain cause cells Central nervous system changes in Characteristics CNS COVID-19 degeneration demonstrated died distribution Effect glial cell glial cells granular hippocampus histological impairment increase in individual mechanisms memory microglia cells MONITOR Morphological morphological change morphology neurodegenerative disorder Neuroinflammation neurological Neuron neuronal neuronal cell organ oxidative stress recent reduce SARS-COV-2 infection Sholl analysis. the disease tissue sample virus while [DOI] 10.1007/s10495-022-01754-9 PMC 바로가기
Neuroinflammation in Dementia-Therapeutic Directions in a COVID-19 Pandemic SettingArticle Published on 2022-09-222022-11-15 Journal: Cells [Category] SARS, 진단, [키워드] activate Activation Affect cognitive complications Concentration COVID-19 cytokine production Dementia direction dysfunction Efficacy Factors Glia glial cell glial cells group of diseases heterogenous highlight human organism IL-1β immune response Inconclusive Inflammation Inflammatory Intervention molecular neurodegenerative Neuroinflammation Neuron NSAID outcome pathology peripheral pro-inflammatory signaling provide resulting risk SARS-CoV-2 setting shown Side effects therapeutic approaches TNF TNF antagonist TNF antagonists while [DOI] 10.3390/cells11192959 PMC 바로가기
TOM70 in Glial Cells as a Potential Target for Treatment of COVID-19Cellular Neuroscience Published on 2021-12-242022-10-31 Journal: Frontiers in Cellular Neuroscience [Category] COVID-19, [키워드] COVID-19 glial cells Mitochondria Neurological symptoms Potential SARS-CoV-2 target TOM70 [DOI] 10.3389/fncel.2021.811376 PMC 바로가기 [Article Type] Cellular Neuroscience
Sex-Specific Microglial Activation and SARS-CoV-2 Receptor Expression Induced by Chronic Unpredictable StressNeuroscience Published on 2021-11-242022-10-31 Journal: Frontiers in Cellular Neuroscience [Category] COVID-19, [키워드] angiotensin-converting enzyme 2 Anxiety Brain changes in chronic chronic unpredictable mild stress coronavirus disease COVID-19 detrimental effect disorders Effect Evidence exacerbate expression female General population glial cells globe Immune homeostasis induced infected patient male MHCII mice microglia Mild monocyte mRNA level Neuroinflammation Neuropsychiatric neuropsychiatric disorders NRP1 pandemic provided receptor receptors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral SARS-CoV2 Stress susceptibility susceptible the SARS-CoV-2 upregulated Withdrawal [DOI] 10.3389/fncel.2021.750373 PMC 바로가기 [Article Type] Neuroscience
The Potential Roles of Glial Cells in the Neuropathogenesis of Cerebral Malaria뇌 말라리아의 신경병리학에서 신경교세포의 잠재적 역할Article Published on 2021-10-072024-08-08 Journal: Frontiers in Cellular and Infection Microbiology [Category] 말라리아, [키워드] astrocytes blood-brain barrier cerebral malaria glial cells microglia Plasmodium [DOI] 10.3389/fcimb.2021.741370 PMC 바로가기
Brainstem neuropathology in two cases of COVID-19: SARS-CoV-2 trafficking between brain and lungCOVID-19의 두 가지 사례에서 뇌간 신경병리학: 뇌와 폐 사이의 SARS-CoV-2 트래피킹Case Reports Published on 2021-05-182022-09-10 Journal: Journal of Neurology [Category] SARS, 치료기술, [키워드] abnormality Activation Anatomy Antigen Autopsies Brain Brainstem brainstem reflex cells controls COVID-19 COVID-19 negative COVID-19 patients cranial cranial nerves demonstrated died element Evidence exhibited expression feature glial cells histopathological examination immunohistochemistry include increase in lung material Medulla oblongata negative patients nervous system Neurological COVID-19 Neuron neuronal Neuropathology oblongata Other pathophysiology Patient reported respiratory centers Respiratory failure Result SARS-Co SARS-CoV-2 SARS-CoV-2 nucleoprotein Spread supplementary material the SARS-CoV-2 two COVID-19 patients two patients vagus nerve Viral widespread [DOI] 10.1007/s00415-021-10604-8 PMC 바로가기 [Article Type] Case Reports
Intercellular viral spread and intracellular transposition of Drosophila gypsy초파리 집시의 세포간 바이러스 전파 및 세포내 전위Research Article Published on 2021-04-222022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence acquisition age aging ancestor animals arthropods assembly Author biological processe biological processes Cancer Cell chromosome chromosomes Combination develop disease Drosophila dysfunction element elements envelope gene Evidence exhibit exogenous retrovirus exogenous retroviruses expressed expression feature functional Genome genomes genomic germ line glial cell glial cells host genome implicated Implications incompatible increasingly infectious intercellular Like Long Long Terminal Repeat murine myriad neurodegeneration Neuron neurons occur organism plant plants Protein question raise related diseases Repeat replicate Replication retrotransposon retrotransposons retroviral retrovirus retroviruses similarity somatic cell somatic cells terminal the cell thought tissue transitioned Transmission Viral viral envelope protein viral spread Viral transmission viruses [DOI] 10.1371/journal.pgen.1009535 PMC 바로가기 [Article Type] Research Article
Does COVID‐19 contribute to development of neurological disease?Review Published on 2020-12-172022-10-30 Journal: Immunity, Inflammation and Disease [Category] COVID-19, MERS, SARS, [키워드] ACE2 ACE2 receptor activated acute respiratory syndrome Brain Central nervous system clinical manifestation CNS consequence Consequences contribute coronavirus coronavirus disease COVID‐19 COVID‐19 patient COVID‐19 database Depression disease Effect enzyme Evidence expected Express glial cell glial cells Healthcare provider immune mediated demyelination infect Infection information kidneys literature review Lungs memory impairment neurodegeneration Neuroinflammation neurological neurological circuits Neurological complication NEUROLOGY Neuron Olfactory epithelium organ Patient Pneumonia recent receptor Region Research Result SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 Standard Transmission virus [DOI] 10.1002/iid3.387 PMC 바로가기 [Article Type] Review