Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assemblyArticle Published on 2024-01-202024-09-05 Journal: Nature Communications [Category] update2024, [키워드] Golgi SARS-CoV-2 [DOI] 10.1038/s41467-024-44958-0 PMC 바로가기 [Article Type] Article
A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPsarticle Published on 2023-12-152024-09-05 Journal: Nature Communications [Category] update2024, [키워드] Biophysical chemistry Golgi SARS-CoV-2 X-ray crystallography [DOI] 10.1038/s41467-023-44076-3 PMC 바로가기 [Article Type] article
Cellular Release of Infectious Hepatitis C Virus Particles via Endosomal PathwaysReview Published on 2023-12-142024-09-05 Journal: Viruses [Category] update2024, [키워드] endosomal sorting complex required for transport machinery Golgi hepatitis C virus multivesicular bodies recycling endosome Release [DOI] 10.3390/v15122430 PMC 바로가기 [Article Type] Review
Extracellular vesicles mediate antibody-resistant transmission of SARS-CoV-2article Published on 2023-01-062024-09-05 Journal: Cell Discovery [Category] update2024, [키워드] Golgi Super-resolution microscopy [DOI] 10.1038/s41421-022-00510-2 PMC 바로가기 [Article Type] article
A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infectionArticle Published on 2022-09-152024-08-29 Journal: Cell Chem Biol [Category] 말라리아, [키워드] CENPJ CRISPR-Cas9 Genome-wide Golgi liver-stage malaria microtubule MTOC Plasmodium vesicular trafficking.
Steric accessibility of the N-terminus improves the titer and quality of recombinant proteins secreted from Komagataella phaffiiArticle Published on 2022-09-052022-11-16 Journal: Microbial Cell Factories [Category] SARS, 변종, [키워드] addition addressed aggregation Alpha Amino acid applied benefit caused Cell cleavage cleave demonstrated eliminated extension extracellular space functional Golgi highest Host IMPROVE Modification N-terminal N-terminus observation occur peptide Pichia Pichia pastoris product Product quality protease Protein protein engineering protein sequence Proteins purification Receptor binding domain Recombinant protein recombinant proteins residue Saccharomyces cerevisiae secrete secreted secreted protein secretion signal signal peptide steric steric hindrance subunit the SARS-CoV-2 the signal peptide therapeutic vaccine antigen variant variants [DOI] 10.1186/s12934-022-01905-2 PMC 바로가기
Genetic variation of Golgi membrane protein 1 is associated with COVID-19 diseaseCorrespondence Published on 2022-07-012022-10-05 Journal: The Journal of Infection [Category] 바이오마커, 유전자 메커니즘, [키워드] disease Golgi membrane protein Variation with COVID-19 [DOI] 10.1016/j.jinf.2022.07.013 [Article Type] Correspondence
The life cycle and enigmatic egress of coronaviruses코로나바이러스의 수명 주기와 불가사의한 탈출Review Published on 2022-06-012022-09-11 Journal: Molecular microbiology [Category] COVID19(2023년), SARS, 치료법, [키워드] adopted alternative route causative agent Cell cell surface cellular Consensus coronavirus CoV CoV infection CoV replication COVID-19 pandemic CoVs drugs Endoplasmic reticulum expression Extracellular genome replication genomic RNA Golgi Golgi apparatus host cell host cells Interference life cycle lumen membrane envelope mobilization nucleocapsid nucleocapsid protein Nucleocapsid proteins pandemic pathway progeny promote Protein rab1 rab11 respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 shown situation the Golgi apparatus the intermediate compartment (IC) the recycling endosome (RE). therapeutic virion assembly virus [DOI] 10.1111/mmi.14907 PMC 바로가기 [Article Type] Review
Identification of SARS-CoV-2 Spike Palmitoylation Inhibitors That Results in Release of Attenuated Virus with Reduced Infectivity감소된 감염성과 함께 약독화된 바이러스의 방출을 초래하는 SARS-CoV-2 스파이크 팔미토일화 억제제의 식별Article Published on 2022-03-042022-09-11 Journal: Viruses [Category] SARS, 변종, [키워드] acylation Antiviral antivirals biogenesis bis-piperazine C-terminal cysteine cysteine residue cytoplasmic DHHC9 domain ER and Golgi FIVE fusion Glycoproteins Golgi identification Infection Infectivity inhibit SARS-CoV-2 inhibitor interact Intervention knockdown membrane fusion palmitate palmitoylation palmitoyltransferase palmitoyltransferase inhibitor Particle piperazine post-translational modifications progeny virion Protein reduced Release released Result resulting S protein S-acylation SARS-CoV-2 SARS-CoV-2 S protein spike Spike mutant Spike protein Spike proteins the SARS-CoV-2 the spike protein transmembrane glycoprotein undergo virus [DOI] 10.3390/v14030531 PMC 바로가기 [Article Type] Article
Analysis of Glycosylation and Disulfide Bonding of Wild-Type SARS-CoV-2 Spike GlycoproteinArticle Published on 2021-11-242023-06-16 Journal: Journal of Virology [Category] COVID19(2023년), MERS, SARS, [키워드] coronavirus COVID-19 Disulfide glycosylation Golgi membrane protein SARS-CoV-2 spike glycoprotein Viral protein virus entry [DOI] 10.1128/jvi.01626-21 PMC 바로가기