Vedolizumab for the prevention of intestinal acute GVHD after allogeneic hematopoietic stem cell transplantation: a randomized phase 3 trialArticle Published on 2024-06-062024-09-05 Journal: Nature Medicine [Category] update2024, [키워드] Graft-versus-host disease Randomized controlled trials [DOI] 10.1038/s41591-024-03016-4 PMC 바로가기 [Article Type] Article
Reconstitution of double-negative T cells after cord blood transplantation and its predictive value for acute graft-versus-host diseaseOriginal Article Published on 2023-08-242024-09-05 Journal: Chinese medical journal [Category] update2024, [키워드] breg cell Double negative T Graft-versus-host disease Hematological malignancies immune reconstitution Treg cell Umbilical cord blood transplantation [DOI] 10.1097/CM9.0000000000002807 PMC 바로가기 [Article Type] Original Article
A prospective phase 2 clinical trial of a C5a complement inhibitor for acute GVHD with lower GI tract involvementArticle Published on 2023-05-182024-09-05 Journal: Bone marrow transplantation [Category] update2024, [키워드] Drug development Graft-versus-host disease [DOI] 10.1038/s41409-023-01996-4 PMC 바로가기 [Article Type] Article
The impact of SARS-CoV2 vaccines on the incidence of graft versus host disease in allogeneic hematopoietic stem cell transplant recipients: a single-center retrospective studyarticle Published on 2023-04-182024-09-05 Journal: Stem Cell Research & Therapy [Category] update2024, [키워드] allogeneic hematopoietic stem cell transplantation BNT162b2 COVID-19 vaccine Graft-versus-host disease mRNA-1273 severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) [DOI] 10.1186/s13287-023-03326-3 PMC 바로가기 [Article Type] article
Predictors of Covid-19 Vaccination Response After In-Vivo T-Cell-Depleted Stem Cell TransplantationArticle Published on 2022-09-012022-11-16 Journal: Transplantation and cellular therapy [Category] COVID19(2023년), SARS, 치료기술, [키워드] age Allogeneic allogeneic transplantation antibody Antibody Response average binding antibody unit Blood donors BNT162b2 chronic GVHD CORD COVID-19 detectable Donor dose Efficacy Graft-versus-host disease GVHD in vivo independent predictor initial involved JNJ-78436735 Johnson & Johnson less Lymphocyte count lymphocyte counts Moderna mRNA-1273 multivariable analysis Patient Predictive Prophylaxis question recipient recipients respond response robust SARS-CoV-2 spike protein SARS-CoV-2 vaccination Serologic response STEM stem cell Stem cell transplantation T cell depletion T-cell T-cell Depletion Transplant transplantation transplants umbilical cord blood vaccination Vaccine [DOI] 10.1016/j.jtct.2022.06.012 PMC 바로가기
Possible Chronic Graft-versus-host Disease in the Central Nervous System Manifesting as Cerebellar Ataxia after Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid LeukemiaCase Report Published on 2022-08-102024-09-04 Journal: Internal medicine (Tokyo, Japan) [Category] 대상포진, [키워드] allogeneic hematopoietic stem cell transplantation Ataxia Central nervous system downbeat nystagmus Graft-versus-host disease leukemia [DOI] 10.2169/internalmedicine.9720-22 PMC 바로가기 [Article Type] Case Report
Immune Responses to SARS-CoV-2 Vaccination in Young Patients with Anti-CD19 Chimeric Antigen Receptor T Cell-Induced B Cell Aplasia항-CD19 키메라 항원 수용체 T 세포 유도 B 세포 무형성증이 있는 젊은 환자에서 SARS-CoV-2 백신 접종에 대한 면역 반응Article Published on 2022-07-012022-09-11 Journal: Transplantation and cellular therapy [Category] COVID19(2023년), MERS, SARS, 바이오마커, 변종, 진단, 치료기술, [키워드] Acute lymphoblastic leukemia acute respiratory syndrome acute respiratory syndrome coronavirus advent adverse events age Anti-CD19 Anti-CD19 CAR T cell-induced B cell aplasia anti-S Antigen antigen receptor aplasia B cell CAR CAR T cell therapy CD19 CD4 CD4/CD8 Cell therapy cellular immunity chimeric antigen receptor Cohort coronavirus coronavirus disease coronavirus disease 19 COVID-19 Cytometry deficiency diagnosed disease Endpoint Exacerbation exhibited expected flow cytometry grade 3 Graft-versus-host disease GVHD healthy healthy controls humoral Humoral response humoral responses Immune cell immune response Immunoglobulin Immunoglobulin G incidence individual induce Infection leukemia Lymphoblastic leukemia lymphocyte Lymphocyte count Lymphocyte subsets mRNA vaccine Mutation Omicron variant outcome Patient precursor primary endpoint Prospective Study PROTECT protective effect recipient Relapse respiratory response risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination second dose secondary Secondary endpoints Seroconversion severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spike protein subsequent T cell T cell response T cell responses T cells T-cell the patient the vaccine therapy treated vaccination Vaccine [DOI] 10.1016/j.jtct.2022.04.017 PMC 바로가기 [Article Type] Article
Association of Host Factors With Antibody Response to Seasonal Influenza Vaccination in Allogeneic Hematopoietic Stem Cell Transplant PatientsArticle Published on 2022-04-152023-06-14 Journal: The Journal of Infectious Diseases [Category] Fulltext, 신종인플루엔자, [키워드] categorical regression Graft-versus-host disease Hemagglutination inhibition titer hematopoietic stem cell transplantation Immunosuppression Influenza sequential model Seroconversion vaccination [DOI] 10.1093/infdis/jiab391 PMC 바로가기
Antibody Response to SARS-CoV-2 Vaccination in Patients following Allogeneic Hematopoietic Cell Transplantation동종 조혈 세포 이식 후 환자에서 SARS-CoV-2 백신 접종에 대한 항체 반응Article Published on 2022-04-012022-09-11 Journal: Transplantation and cellular therapy [Category] COVID19(2023년), SARS, 치료법, [키워드] age Allogeneic Allogeneic hematopoietic cell transplantation Analysis antibody antibody levels Antibody Response Antibody titer Antibody titers approved BNT162b2 Cell cell transplantation chronic GVHD Cohort conditioning regimen conducted Critical disease domain Efficacy examined Factor Graft-versus-host disease group GVHD had no healthy control healthy controls healthy volunteers hematopoietic Hematopoietic cell transplantation highest homogenous humoral immune response IgA IgG IgM immune response immune responses Immunocompromised patients Immunosuppression information intensity Moderna mRNA mRNA vaccine mRNA vaccines mRNA-1273 nucleocapsid protein pandemic Patient physician reactivity receiving Receptor-binding domain recipient recipients regimen response revaccination S1 and S2 SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-CoV-2 pandemic SARS-CoV-2 vaccination second dose significantly lower single center spike glycoprotein stratified subunit Switzerland the SARS-CoV-2 the vaccine transplantation Treatment underlying disease vaccination Vaccine waned was performed [DOI] 10.1016/j.jtct.2022.01.019 PMC 바로가기 [Article Type] Article
Humoral serological response to the BNT162b2 vaccine after allogeneic haematopoietic cell transplantation동종 조혈 세포 이식 후 BNT162b2 백신에 대한 체액 혈청 반응Article Published on 2022-02-012022-09-12 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% confidence interval 95%CI Allogeneic Allogeneic haematopoietic cell transplantation anti-spike antibodies BNT162b2 BNT162b2 vaccine Cell cell transplantation chronic GVHD Cohort comparable declined demonstrated disease General population Graft-versus-host disease GVHD HCT humoral humoral immune response Immunosuppression moderate Odds ratio Patient patients precautions proportion prospective cohort study quantitative measurement receiving recipient reported SARS-CoV-2 serological response seronegative seronegative patient Symptom vaccination was performed worsened [DOI] 10.1016/j.cmi.2021.10.007 PMC 바로가기 [Article Type] Article