rVSV-ΔG-SARS-CoV-2-S vaccine: repeated intramuscular (IM) toxicity, local tolerance, immunogenicity and biodistribution study in NZW rabbitsrVSV-ΔG-SARS-CoV-2-S 백신: NZW 토끼에서 반복되는 근육내(IM) 독성, 국소 내성, 면역원성 및 생체 분포 연구Article Published on 2022-08-012022-09-11 Journal: Archives of Toxicology [Category] COVID19(2023년), MERS, SARS, 비임상, 진단, 치료기술, [키워드] Administered animals antibody antibody levels Antibody titers Antigen assigned binding biodistribution biodistribution study body temperature body weight breath C-reactive protein change Clinical pathology Clinical signs clinical trial clinical trials correlated COVID-19 detection elicited evaluate Express followed by Gross High-dose high-dose group histopathological iliac lymph node immunogenicity inflammatory reaction injection intervals intramuscular intramuscularly Local local reactions Lymph node mesenteric lymph nodes Necrosis Neutralizing antibodies Neutralizing antibody titer neutralizing antibody titers New Nonclinical ophthalmology pathology Phase 2 platform Reactions repeated RNA Safe Safety SARS-CoV-2 SARS-CoV-2-S significant increase spleen stomatitis supported systemic the vaccine Tolerance Toxicity two group two groups Urinalysis vaccination Vaccine vaccine doses Vector-based vaccine vesicular stomatitis vesicular stomatitis virus Viremia VSV was performed [DOI] 10.1007/s00204-022-03302-5 PMC 바로가기 [Article Type] Article
Stillbirth due to SARS-CoV-2 placentitis without evidence of intrauterine transmission to fetus: association with maternal risk factors태아에 대한 자궁내 전파의 증거가 없는 SARS-CoV-2 태반염으로 인한 사산: 산모 위험 인자와의 연관성Multicenter Study Published on 2022-06-012022-09-11 Journal: Ultrasound in obstetrics & gynecology : the offici [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected affecting Analysis asphyctic association Asymptomatic Autopsy carried caused Chain Reaction characterized Clinical characteristics Combination coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis death demise diagnosed electron microscopy Evidence evidence of examined Factor Factors fetal fetal death fetal infection fetus FGR Greece Gross growth Gynecology histological histological change histopathological identify immunostaining independent Infection Inflammatory intervillous space intrauterine fetal death lesion less live birth Microscopy mild clinical symptom mild clinical symptoms molecular mother multicenter Multiple multiple sclerosis Neonates no evidence of obstetrics occurred organs pathology Placenta placental Placentas placentitis polymerase chain polymerase chain reaction positive potential risk predisposing factors pregnancies Pregnancy pregnant women prenatally ranged Regression regression analysis respiratory retrieved risk risk factor Risk factors SARS-CoV-2 SARS-CoV-2 placentitis SARS-CoV-2 spike protein Seven severe acute respiratory syndrome Coronavirus Society Spike protein Stillbirth stillborn Thrombophilia tissues Transmission Ultrasound Viral Viral transmission virion virions was performed was used [DOI] 10.1002/uog.24906 PMC 바로가기 [Article Type] Multicenter Study
Economic losses from COVID-19 cases in the Philippines: a dynamic model of health and economic policy trade-offs Research Published on 2022-04-042022-10-05 Journal: Humanities & Social Sciences Communications [Category] 치료기술, 치료법, [키워드] Analysis average Capital Combination country COVID-19 case COVID-19 infection COVID-19 pandemic cumulative expand Government Gross Health health system health-care high risk IMPROVE include lockdown lockdown policies lockdown policy mathematical measure Measures mechanism proceed product Region Regional regions SEIR Spread subject the disease threshold trade-off Transmission virus [DOI] 10.1057/s41599-022-01125-4 [Article Type] Research
IgA Nephropathy with Gross Hematuria Following COVID-19 mRNA VaccinationCOVID-19 mRNA 백신 접종 후 심한 혈뇨를 동반한 IgA 신병증Case Reports Published on 2022-04-012022-09-12 Journal: Internal medicine (Tokyo, Japan) [Category] Coronavirus, MERS, 진단, [키워드] administration BNT162b2 Cell conducted COVID-19 diagnosed Disease progression elicit Gross gross hematuria Hematuria IgA IgA nephropathy immune activation increase in medication mesangial region Mild mRNA mRNA vaccine nephropathy progression renal second dose vaccination Vaccine [DOI] 10.2169/internalmedicine.8787-21 PMC 바로가기 [Article Type] Case Reports
Fire association with respiratory disease and COVID-19 complications in the State of Pará, BrazilResearch article Published on 2022-02-012022-10-05 Journal: The Lancet Regional Health - Americas [Category] 유전자 메커니즘, [키워드] accompanied affected Algorithm Analysis ARIMAX association average Brazil caused Cluster Clustering confidence level contribute COVID COVID-19 COVID-19 complication COVID-19 mortality COVID-19 pandemic Critical death deaths development environmental factor evaluate Exogenous finding fire funding funding source GDP Gross group Health high mortality rate highest highlight Hospitalization hospitalizations Human identify incidence rate Incidence rate ratio index K-Means knowledge lowest measure Mortality mortality rate mortality risk Occurrence Pandemics problem product public health Region required Respiratory disease respiratory diseases risk SARS-CoV-2 selected serial correlation state Support Time series analysis [DOI] 10.1016/j.lana.2021.100102 [Article Type] Research article
Discovering spatial-temporal patterns via complex networks in investigating COVID-19 pandemic in the United StatesResearch article Published on 2022-02-012022-10-05 Journal: Sustainable Cities and Society [Category] 치료기술, [키워드] adopted Analysis approach Characteristics Community complementary complex Complex network component COVID-19 COVID-19 pandemic COVID-19 progression data-driven diffusion epidemiological Evolution Factor GDP Gross help hidden highest information Intervention knowledge mapped Metrics Online random forest prediction pandemic PCA Perspective principal product random response significantly the United State Time series analysis unique [DOI] 10.1016/j.scs.2021.103508 [Article Type] Research article
Placental deficiency during maternal SARS-CoV-2 infection산모의 SARS-CoV-2 감염 중 태반 결핍Multicenter Study Published on 2022-01-012022-09-12 Journal: Placenta [Category] MERS, SARS, 진단, [키워드] abnormality age anti-SARS-CoV-2 anti-SARS-CoV-2 IgM antibody change Clinical severity collected Concentration correlated COVID-19 cross deficiency disease evaluate feature fetal Gross histopathological indicated Infection Maternal moderate mother Nasopharyngeal swab Neonatal Neonate Neonates outcome outcomes pathology Placenta placental Placental infection Placental pathological findings positive Pregnancy pregnant women prospective cohort study Prospective Study Protein reported risk SARS- CoV-2 SARS-CoV-2 SARS-COV-2 infection sera severe disease severity spike staining structures Swab the disease transmission of SARS-CoV-2 umbilical [DOI] 10.1016/j.placenta.2021.10.012 PMC 바로가기 [Article Type] Multicenter Study
Non-Pharmaceutical Interventions against COVID-19 Pandemic: Review of Contact Tracing and Social Distancing Technologies, Protocols, Apps, Security and Open Research DirectionsReview Published on 2021-12-302022-10-29 Journal: Sensors (Basel, Switzerland) [Category] COVID-19, SARS, [키워드] addition adopted artificial intelligence assist combating concerning Contact tracing coronavirus disease country COVID-19 died direction disease effective effort GDP Government Gross high risk highlight infecting Interaction Internet of Things maintain majority product protocols Psychological Public health intervention recommendation Research researchers review security sensor technologies social distancing spread of COVID-19 the disease tracing Transmission [DOI] 10.3390/s22010280 PMC 바로가기 [Article Type] Review
Temporal Patterns of COVID-19-Associated Pulmonary Pathology: An Autopsy StudyPathology Published on 2021-12-192022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory distress age alveolar alveolar cell Autopsy Bulgaria cause Cell change changes in clinical complication clinically Cohort coronavirus COVID-19 criteria develop disease disease onset distress Endotheliitis Endothelitis expired female fibrosis Gross Hematoxylin and eosin Histopathology hyaline membrane independent Infection interstitial light microscopy long-lasting lung changes Lungs male manifested Marina material mechanism morbidity and mortality notable Novel coronavirus novel coronavirus disease pathology Patient pattern polymerase chain Probability pulmonary pulmonary morphology Pulmonary pathology respiratory tract Result SARS-CoV-2 selected severe complication severe COVID-19 severe disease severity significantly increased squamous cell metaplasia symptom onset syndrome Temporal the disease the mean Type II pneumocyte university variant Varna Vascular withdrawn [DOI] 10.7759/cureus.20522 PMC 바로가기 [Article Type] Pathology
An outbreak of SARS-CoV-2 with high mortality in mink ( Neovison vison) on multiple Utah farms여러 유타 농장에서 밍크(Neovison vison)의 사망률이 높은 SARS-CoV-2 발생Research Article Published on 2021-11-122022-09-12 Journal: PLoS Pathogens [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Animal host animal hosts animals anorexia bat bats breadth caused Chain Reaction clinical disease collected coronavirus damage death demonstrated disease distribution early phase edema effort epithelial F486L FIVE Gross high mortality hosts Human humans In situ hybridization indicate information interstitial pneumonia Localization localized infection lower respiratory system lung Lymph node measure mink moderate molecular Mortality multiple organ multiple organs Mutation nasal turbinates necropsy Neovison Novel coronavirus occurred outbreak pathology perivasculitis polymerase chain polymerase chain reaction Polymorphisms potential transmission PPE Prevent provided pulmonary congestion Pulmonary edema RBD mutation reported reservoir reservoirs Respiratory disease respiratory tract reveal reverse transcriptase Reverse transcriptase polymerase chain reaction RT-PCR SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 viral RNA sequenced severe acute respiratory syndrome Coronavirus severe respiratory disease Spread strain susceptible symptomatic the disease The United States tissue tissues tracheobronchial Transmission unique United States upper respiratory tract Utah Vasculitis viral infection Viral RNA Viral transmission virus virus transmission while whole genome Whole genome sequencing Y453F [DOI] 10.1371/journal.ppat.1009952 PMC 바로가기 [Article Type] Research Article