Dysregulation of Plasma Growth Factors and Chemokines in Cocaine Use Disorder: Implications for Dual Diagnosis with Schizophrenia and Antisocial Personality Disorder in an Exploratory StudyResearch Article Published on 2024-05-202024-09-05 Journal: Neuropsychobiology [Category] update2024, [키워드] Antisocial personality disorder BDNF chemokines cocaine Dual diagnosis Eotaxin-1 Growth factors Schizophrenia [DOI] 10.1159/000536265 PMC 바로가기 [Article Type] Research Article
Elucidating systemic immune responses to acute and convalescent SARS‐CoV‐2 infection in children and elderly individualsOriginal Article Published on 2024-02-012024-09-05 Journal: Immunity, Inflammation and Disease [Category] update2024, [키워드] acute phase proteins chemokines children complement components COVID‐19 Cytokines elderly Growth factors [DOI] 10.1002/iid3.1167 PMC 바로가기 [Article Type] Original Article
Changes in chemokine and growth factor levels may be useful biomarkers for monitoring disease severity in COVID-19 patients; a pilot studyImmunology Original Research Published on 2024-01-042024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] chemokines COVID-19 Growth factors MEWS score SARS-CoV-2 [DOI] 10.3389/fimmu.2023.1320362 PMC 바로가기 [Article Type] Immunology Original Research
Serum biomarkers associated with SARS-CoV-2 severityArticle Published on 2022-09-262022-11-15 Journal: Scientific Reports [Category] SARS, 바이오마커, [키워드] acute phase Angiogenesis Asymptomatic biological marker Biomarker cardiovascular diseases chemokine Clinical course controls correlated cytokine D-dimer disease disease severity elevated evaluated Factor group groups Growth factors help Hospitalized identify immune response individual infected with SARS-CoV-2 Infection Mild negative control Patient patients with SARS-CoV-2 prognostic Prognostic markers RT-PCR SARS-CoV-2 SARS-COV-2 infection sera Severe case severity [DOI] 10.1038/s41598-022-20062-5 PMC 바로가기
The Bovine Seminal Plasma Protein PDC-109 Possesses Pan-Antiviral ActivityArticle Published on 2022-09-132022-11-15 Journal: Viruses [Category] SARS, 치료제, [키워드] accompanied activity affected antiviral activity bovine Bovine seminal plasma Cell component components concentrations COVID-19 Cytokines cytotoxicity demonstrated elements etiological agent experiment Fn-type 2 proteins function Glucose glycoprotein Growth factors impair Infection infections Infectious disease Influenza virus inhibit investigated limit lipids mammalian membrane fusion metabolites Particle PDC-109 plasma plasma protein Proteins reporter respiratory SARS-CoV-2 Seminal sexual transmission significantly spike treatment regimen viability viral infection virus virus inhibition virus particles VSV VSV replicon. without affecting [DOI] 10.3390/v14092031 PMC 바로가기
Immunomodulatory Mechanisms of Mesenchymal Stem Cells and Their Potential Clinical ApplicationsArticle Published on 2022-09-022022-11-16 Journal: International Journal of Molecular Sciences [Category] 유전자 메커니즘, [키워드] application Autoimmune disease Cell Characteristics chemokines clinical Clinical applications Contact contribute COVID-19 Cytokines disease Diseases Effect Engineering Factor Growth factors homing immune immune cells immune disorders Immune homeostasis immune response immunomodulation immunomodulatory immunomodulatory effect immunomodulatory property IMPROVE incurable Inflammatory diseases Inflammatory responses maintain mechanism mesenchymal stem cell mesenchymal stem cells (MSCs). MSC MSCs multifunctional Potential regenerative Regulation Secretome shown signaling molecules STEM stem cell systemic lupus erythematosus therapeutic strategy treat [DOI] 10.3390/ijms231710023 PMC 바로가기
SARS-CoV-2 infection- induced growth factors play differential roles in COVID-19 pathogenesisSARS-CoV-2 감염 유발 성장 인자는 COVID-19 발병 기전에서 다른 역할을 합니다Article Published on 2022-09-012022-09-11 Journal: Life sciences [Category] COVID19(2023년), MERS, SARS, 바이오마커, 치료기술, [키워드] adverse effect adverse effects angiopoietin association COVID-19 COVID-19 pathogenesis COVID-19 patient Critical Critically ill cytokine Cytokine storm Cytokine storms Cytokines D-dimer disease dysregulation EGF elevated Endothelial dysfunction EPO erythropoietin exhibited G-CSF growth factor Growth factors HGF Hospitalized ICU Inflammation Injury inverse correlation investigation marker moderate Myoglobin negative correlation non-ICU occur P-selectin Pathogenesis pathogenesis of COVID-19 pathophysiology PDGF plasma positive correlation reflected remained repair SARS-COV-2 infection selectin specific disease Thromboembolism tissue tissue injury Tissue injury. upregulated vague VEGF was performed [DOI] 10.1016/j.lfs.2022.120703 PMC 바로가기 [Article Type] Article
Effectiveness, safety, and immunogenicity of half dose ChAdOx1 nCoV-19 COVID-19 Vaccine: Viana projectArticle Published on 2022-08-292022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] adverse event age and sex analyzed anti-SARS-CoV-2 baseline Biomarker booster dose ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine chemiluminescence chemokines Concentration Controlled trial COVID-19 Cytokines death dose effective Effectiveness evaluated exclusion first dose Fractional dose Frequency geometric mean Growth factors healthcare worker Hospitalization immune response immunization immunoassay immunogenic immunogenicity incidence incidence rate increase in indicate individual individuals multiplex neutralizing antibody non-inferiority non-randomized plaque reduction neutralization plasma pre-immune primary endpoint PRNT Protein quantified RBD Receptor binding domain Registered reported RT-PCR Safe Safety second dose Serious Adverse Event seroconversion rate seronegative seropositive seropositive subject SUS Vaccine Vaccines [DOI] 10.3389/fimmu.2022.966416 PMC 바로가기
Maternal vaccination as an additional approach to improve the protection of the nursling: Anti-infective properties of breast milkArticle Published on 2022-08-102022-11-15 Journal: Clinics [Category] 진단, [키워드] anti-SARS-CoV-2 anti-SARS-CoV-2 vaccines antibody Antibody Response approach B lymphocyte bacterial antigen Bioactive factors Breast breast milk Breastfeeding chemokines complement component cytokine elevated Factors fatty acids function Growth factors hormone Human IgA IgA antibodies IgA antibody IgG antibody IMPROVE inactivated induce lactation lactoferrin leukocyte mammary Maternal maternal immunization MicroRNAs nucleic acids oligosaccharides pandemic passive immunity performed Placenta Plasma cell plethora polysaccharide Pregnancy produced Proteins respiratory infections respiratory tracts secretion secretory secretory IgA Secretory IgA antibodies. Specific specific antibody unique vaccination Vaccine Vaccines virus virus-neutralizing viruses [DOI] 10.1016/j.clinsp.2022.100093 PMC 바로가기
Platelets in the NETworks interweaving inflammation and thrombosis염증과 혈전을 뒤섞는 NETworks의 혈소판Review Published on 2022-08-012022-09-11 Journal: Frontiers in Immunology [Category] 치료기술, 치료제, [키워드] activate Bacterial Capillaries capillary characterized chemokine chemokines chromatin Clinical outcome Coagulation factors contribute contributing to Course COVID-19 COVID-19 pandemic COVID-19 patient Cytokine storm disease DNA engage ENhance Evidence expression Extracellular extracellular space Growth factors hemorrhage Hemostasis histone Histones host innate immunity immune response immunothrombosis IMPROVE increased mortality induce infiltration Inflammation Inflammatory diseases inflammatory signaling Interaction interface kill lesion lung majority mechanism microthrombi molecular mechanism NET NETs neutrophil neutrophil activation Neutrophil extracellular trap Neutrophil extracellular traps neutrophil infiltration Neutrophils other tissue other tissues pathogen Pathogens Pathways Patient Pattern recognition Pattern recognition receptors Platelet Platelets procoagulant Protein Proteins provide provided resulting signaling pathway subsequent surface expression survival target thrombi thrombosis thrombotic TLR2 TLR4 Topic TRAP Treatment vascular beds virus [DOI] 10.3389/fimmu.2022.953129 PMC 바로가기 [Article Type] Review