A Systematic Study on the Optimal Nucleotide Analogue Concentration and Rate Limiting Nucleotide of the SARS-CoV-2 RNA-Dependent RNA PolymeraseSARS-CoV-2 RNA 의존성 RNA 중합효소의 최적 뉴클레오티드 유사체 농도 및 속도 제한 뉴클레오티드에 대한 체계적인 연구Article Published on 2022-07-272022-09-11 Journal: International Journal of Molecular Sciences [Category] [DOI] 10.3390/ijms23158302 PMC 바로가기 [Article Type] Article
The impact of obesity and dyslipidemia on Remdesivir effectiveness in hospitalized patients with SARS-CoV-2-related pneumonia: An observational studySARS-CoV-2 관련 폐렴으로 입원한 환자에서 비만과 이상지질혈증이 렘데시비르 효과에 미치는 영향: 관찰 연구Observational Study Published on 2022-07-012022-09-11 Journal: Nutrition, metabolism, and cardiovascular diseases [Category] [DOI] 10.1016/j.numecd.2022.04.005 PMC 바로가기 [Article Type] Observational Study
Comparative Greenness Metric Estimates for Content Uniformity Testing of Anti-Cov-2, GS-5734 in Commercial Vials: Validated Micellar Electrokinetic Chromatographic Assay상업용 바이알에서 Anti-Cov-2, GS-5734의 함량 균일성 테스트에 대한 비교 녹색도 측정법 추정: 검증된 미셀 동전기 크로마토그래피 분석Article Published on 2022-04-272022-09-11 Journal: Journal of AOAC International [Category] [DOI] 10.1093/jaoacint/qsac001 PMC 바로가기 [Article Type] Article
The development of broad-spectrum antiviral medical countermeasures to treat viral hemorrhagic fevers caused by natural or weaponized virus infectionsReview Published on 2022-03-082022-10-28 Journal: PLoS Neglected Tropical Diseases [Category] [DOI] 10.1371/journal.pntd.0010220 PMC 바로가기 [Article Type] Review
Broad-Spectrum In Vitro Antiviral Activity of ODBG-P-RVn: An Orally-Available, Lipid-Modified Monophosphate Prodrug of Remdesivir Parent Nucleoside (GS-441524)Article Published on 2021-11-242023-07-02 Journal: Microbiology Spectrum [Category] [DOI] 10.1128/Spectrum.01537-21 PMC 바로가기
Remdesivir: Quo vadis?렘데시비르: 쿼바디스?Review Published on 2021-11-012022-09-11 Journal: Biochemical pharmacology [Category] [DOI] 10.1016/j.bcp.2021.114800 PMC 바로가기 [Article Type] Review
Why Remdesivir Failed: Preclinical Assumptions Overestimate the Clinical Efficacy of Remdesivir for COVID-19 and Ebola렘데시비르가 실패한 이유: 전임상 가정이 COVID-19 및 에볼라에 대한 렘데시비르의 임상 효능을 과대평가함Article Published on 2021-09-172022-09-11 Journal: Antimicrobial Agents and Chemotherapy [Category] [DOI] 10.1128/AAC.01117-21 PMC 바로가기 [Article Type] Article
Broad-spectrum in vitro antiviral activity of ODBG-P-RVn: an orally-available, lipid-modified monophosphate prodrug of remdesivir parent nucleoside (GS-441524)Article Published on 2021-08-102023-08-29 Journal: bioRxiv [Category] [DOI] 10.1101/2021.08.06.455494 PMC 바로가기 [Article Type] Article
A combined assay for quantifying remdesivir and its metabolite, along with dexamethasone, in serum혈청 내 렘데시비르 및 덱사메타손과 함께 렘데시비르의 대사 산물을 정량화하기 위한 결합 분석Article Published on 2021-06-182022-09-11 Journal: Journal of Antimicrobial Chemotherapy [Category] [DOI] 10.1093/jac/dkab094 PMC 바로가기 [Article Type] Article
Key Metabolic Enzymes Involved in Remdesivir Activation in Human Lung Cells인간 폐 세포에서 Remdesivir 활성화에 관여하는 주요 대사 효소Antiviral Agents Published on 2021-06-142022-09-10 Journal: Antimicrobial Agents and Chemotherapy [Category] [DOI] 10.1128/AAC.00602-21 PMC 바로가기 [Article Type] Antiviral Agents