The Impact of Sleep on Haematological Parameters in FirefightersArticle Published on 2024-06-262024-09-05 Journal: Clocks & Sleep [Category] update2024, [키워드] circadian rhythms Haematocrit Haemoglobin PSQI [DOI] 10.3390/clockssleep6030021 PMC 바로가기 [Article Type] Article
Clinical features and high-resolution chest computerized tomography findings of children infected by the B.1.617.2 variant of coronavirus disease 2019Article Published on 2022-12-012022-11-16 Journal: Annals of Medicine [Category] COVID19(2023년), SARS, 변종, [키워드] absence age analysed analyses B.1.617.2 B.1.617.2 (Delta) variant biochemical Blood Cell Chest Chest CT chest. children China clinical clinical symptom Clinical symptoms collected Computerized tomography Concentration consolidation coronavirus disease corpuscular correlated correlation cough COVID-19 CT CT finding Delta Diagnosis Disease diagnosis disease stage distribution elevated Factor feature Fever Follow-up ground-glass opacity group Haemoglobin High-resolution imaging Infection Laboratory Laboratory tests lymphocyte males Mild monocyte Nanjing no difference pathological change Patient percentage pharyngeal Platelet regression analysis serum alkaline phosphatase significant effect Stage stages statistically significant Subtypes Symptom Symptoms the disease variant Volume [DOI] 10.1080/07853890.2022.2114608 PMC 바로가기
Early but reversible haemostatic changes in a-symptomatic females expressing COVID-19 antibodiesCOVID-19 항체를 발현하는 무증상 여성의 초기이지만 가역적인 지혈 변화Article Published on 2022-09-012022-09-12 Journal: Thrombosis research [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] age and gender aggregation antibody Antibody Response Asymptomatic COVID-19 carried change changes in circulating coagulation parameter Cohort cohort study Control coronavirus country COVID-19 COVID-19 antibody COVID-19 pandemic COVID-19-associated coagulopathy Effect effort expressing extracellular vesicle female Female patients globe Haemoglobin highest IgM and IgG individual Infection initial intensive care treatment male Mortality participant Participants pathway Platelet platelet activation Platelet responsiveness. positive positive COVID-19 Prevalence Prothrombin time risk serious complication significant decrease significant increase Spread subject unique vaccination Vaccine viral mutation were assessed with COVID-19 [DOI] 10.1016/j.thromres.2022.07.012 PMC 바로가기 [Article Type] Article
Severe refractory warm autoimmune haemolytic anaemia after the SARS-CoV-2 Pfizer-BioNTech vaccine (BNT162b2 mRNA) managed with emergency splenectomy and complement inhibition with eculizumabArticle Published on 2022-08-312022-11-15 Journal: BMJ case reports [Category] SARS, 진단, [키워드] 48 hour Autoimmune Bilirubin Blood BNT162b2 mRNA Chest complement Complement pathway Corticosteroid described disease eculizumab fatigue first dose haematology (incl blood transfusion) Haemoglobin highlight inhibitor initiated investigation jaundice lactate dehydrogenase life-threatening liver male over Pfizer-BioNTech SARS-CoV-2 standard treatment the patient the SARS-CoV-2 transplantation Urine Vaccine warm was performed [DOI] 10.1136/bcr-2022-250774 PMC 바로가기
A phase 1b randomised controlled trial of a glucagon-like peptide-1 and glucagon receptor dual agonist IBI362 (LY3305677) in Chinese patients with type 2 diabetes Research Published on 2022-06-242022-10-05 Journal: Nature Communications [Category] 임상, 진단, [키워드] agonist Analysis baseline blood glucose China Chinese patient clinically Cohort cohorts conducted decreased appetite develop diarrhoea effective Efficacy effort eight enrolled evaluate Glucose Haemoglobin investigator involved MOST nausea nine obesity Open-label outcome Patient patients Placebo placebo-controlled plasma randomised randomised controlled trial receive receiving receptor reduced reductions in safety profile secondary subcutaneously T2D Tolerability Tolerance treat Treatment treatment-emergent adverse event type 2 diabete [DOI] 10.1038/s41467-022-31328-x [Article Type] Research
The clinical features and estimated incidence of MIS-C in Cape Town, South Africa남아프리카 케이프타운에서 MIS-C의 임상적 특징 및 추정 발생률Article Published on 2022-05-022022-09-12 Journal: BMC Pediatrics [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] abdominal pain Affect age Analysis black calculated Cape cardiac children children with MIS-C clinical clinical feature clinical manifestation Coagulation Cohort collected comparison CRP D-dimer deaths demographic data Diagnosis eight Epidemiology ferritin Fever fibrinogen global health Haemoglobin healthy children highlight hospital Hospital stay ICU admission immune incidence independent Infection Inflammatory intravenous invasive ventilation involved lack Logistic regression Low-middle income countries marker median median age Methylprednisolone MIS-C neutrophil count organ system outcome Oxygen therapy paediatrics pandemic performed Peritoneal dialysis Rash recruited renal required SARS-CoV-2 SARS-CoV-2 antibodies serum Seven sodium South Africa Support Surveillance syndrome Tachycardia the healthy town Treatment was tested white cell [DOI] 10.1186/s12887-022-03308-z PMC 바로가기 [Article Type] Article
Hybrid closed-loop glucose control compared with sensor augmented pump therapy in older adults with type 1 diabetes: an open-label multicentre, multinational, randomised, crossover studyRandomized Controlled Trial Published on 2022-03-012022-10-05 Journal: The Lancet. Healthy longevity [Category] 임상, [키워드] adverse event age assigned baseline block Cambridge Characteristics clinically COVID-19 death diabete diabetes effective enrolled event Glucose glycaemic control Haemoglobin hospital hybrid Hydrocortisone Hypothesis insulin intention-to-treat median multicentre occurred Older older adult Open-label participant primary endpoint proportion random randomisation randomised Randomly Registered resulting risk risk factor Safe sequence significantly higher stratified the primary endpoint therapy Treatment with COVID-19 [DOI] 10.1016/S2666-7568(22)00005-8 PMC 바로가기 [Article Type] Randomized Controlled Trial
A randomised double-blind placebo-controlled clinical trial of oral hydroxyurea for transfusion-dependent β-thalassaemiaArticle Published on 2022-02-172022-10-04 Journal: Scientific Reports [Category] 임상, [키워드] 1:1 Alter Anaemia assigned Block randomisation Blood Cell Concentration conducted disease double-blind Efficacy and safety evaluate fetal Genotype Haemoglobin hydroxyurea increases in induce ineffective erythropoiesis Patient patients Placebo placebo-controlled clinical trial polymorphism proportion randomised Randomized controlled trials receptor reduced reductions in required response significantly higher significantly lower stratified Stress Therapeutics Transferrin Treatment Volume [DOI] 10.1038/s41598-022-06774-8 PMC 바로가기 [Article Type] Article
Atypical lymphoid cells circulating in blood in COVID-19 infection: morphology, immunophenotype and prognosis valueCOVID-19 감염에서 혈액에서 순환하는 비정형 림프 세포: 형태, 면역 표현형 및 예후 값Article Published on 2022-02-012022-09-11 Journal: Journal of Clinical Pathology [Category] 바이오마커, 치료기술, [키워드] Accuracy activated analysed Analysis approach Atypical lymphocyte automatically Blood blood sample Blood samples blue CD4 CD8 T cells Characteristics circulating classical clinical CNNs Convolutional neural network Convolutional neural networks COVID-19 COVID-19 patient COVID-19 patients Cytometry cytoplasm D-dimer develop Digital image effector memory ENhance Evolution filtration rate glomerular filtration rate Haemoglobin Immunophenotyping Laboratory lymphocyte Lymphocyte count lymphocyte counts Lymphocytes lymphoid cell Morphological morphological and microscopic findings morphology Neutrophils nucleus outcome Patient patients died patients without COVID-19 procalcitonin Prognosis Protein reactive reported sensitivity specificity T cells these cell These cells total protein virus-specific T cell viruses was performed were used [DOI] 10.1136/jclinpath-2020-207087 PMC 바로가기 [Article Type] Article
SARS-CoV-2 in Egypt: epidemiology, clinical characterization and bioinformatics analysisResearch Article Published on 2022-01-312022-10-31 Journal: Heliyon [Category] COVID-19, [키워드] age average B.1 Bioinformatics analysis C-reactive protein caused clade clinical Clinical data clinical symptom collected conducted coronavirus COVID-19 CT finding D-dimer dry cough epidemiological Epidemiology Evolution feature Fever GenBank Genome genomic sequencing Haemoglobin Haplotype haplotypes identity Illumina Infectious disease isolate Laboratory Lineage lymphocytopenia male Mutation NCBI pandemic participant patients Pneumonia predominant reported resulting rRT-PCR SARS-CoV-2 SARS-CoV-2 variant sequence sequenced Serum ferritin Spread strain submitted suspected patient Swab System unique variant virus was performed Whole genome sequencing Wuhan-Hu-1 [DOI] 10.1016/j.heliyon.2022.e08864 PMC 바로가기 [Article Type] Research Article