Repurposing screen identifies novel candidates for broad-spectrum coronavirus antivirals and druggable host targetsAntiviral Agents Published on 2024-03-062024-09-05 Journal: Med Instrum [Category] update2024, [키워드] antivirals coronavirus CRISPR/Cas9 HCoV-229E host-targeting antiviral therapy repurposing SARS-CoV-2 [DOI] 10.1128/aac.01210-23 PMC 바로가기 [Article Type] Antiviral Agents
Clear polyurethane coatings with excellent virucidal properties: Preparation, characterization and rapid inactivation of human coronaviruses 229E and SARS-CoV-2Article Published on 2023-04-292024-09-05 Journal: Applied Materials Today [Category] update2024, [키워드] HCoV-229E N-halamines Polyurethanes Reinfection SARS-CoV-2 Virucidal coatings [DOI] 10.1016/j.apmt.2023.101828 PMC 바로가기 [Article Type] Article
Structural basis of main proteases of HCoV-229E bound to inhibitor PF-07304814 and PF-07321332Article Published on 2023-03-172024-09-05 Journal: Biochemical and Biophysical Research Communication [Category] update2024, [키워드] HCoV-229E inhibitor main protease PF-07304814 PF-07321332 [DOI] 10.1016/j.bbrc.2023.03.043 PMC 바로가기 [Article Type] Article
Mouse models susceptible to HCoV-229E and HCoV-NL63 and cross protection from challenge with SARS-CoV-2Biological Sciences Published on 2023-01-182024-09-05 Journal: Proceedings of the National Academy of Sciences of [Category] update2024, [키워드] HCoV-229E HCoV-NL63 mouse model SARS-CoV-2 Therapeutics Vaccine [DOI] 10.1073/pnas.2202820120 PMC 바로가기 [Article Type] Biological Sciences
Epidemiology of Non-SARS-CoV2 Human Coronaviruses (HCoVs) in People Presenting with Influenza-like Illness (ILI) or Severe Acute Respiratory Infections (SARI) in Senegal from 2012 to 2020Article Published on 2022-12-212023-07-11 Journal: Viruses [Category] COVID19(2023년), [키워드] coronavirus characterization Epidemiology HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 human coronaviruses ILI respiratory infections SARI [DOI] 10.3390/v15010020 PMC 바로가기
Calibration of Methods for SARS-CoV-2 Environmental Surveillance: A Case Study from Northwest TuscanyArticle Published on 2022-12-092023-07-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), [키워드] HCoV-229E mengovirus VMC0 SARS-CoV-2 wastewater surveillance Wastewater-based epidemiology [DOI] 10.3390/ijerph192416588 PMC 바로가기
Antigenic mapping reveals sites of vulnerability on α-HCoV spike proteinArticle Published on 2022-11-042022-11-15 Journal: Communications Biology [Category] SARS, 진단, [키워드] antigenic appear characterized conserved distal domain dominant effective epitope Epitopes feasibility HCoV-229E HCoV-NL63 highlight human coronavirus imperative N-terminal domain Neutralizing neutralizing antibody panel of antibody Protein RBD Receptor binding domain receptor binding site recognize representing reveal S protein S proteins similarity spike Spike protein subset the SARS-CoV-2 understanding Vaccine design Vaccine development [DOI] 10.1038/s42003-022-04160-8 PMC 바로가기
More tools for our toolkit: The application of HEL-299 cells and dsRNA-nanoparticles to study human coronaviruses in vitroArticle Published on 2022-11-012022-11-15 Journal: Virus research [Category] SARS, 치료법, 치료제, [키워드] ACE2 receptor Analysis Antiviral antiviral genes antiviral response antiviral therapy can be used Cell cell line cells Combination competent Complete coronavirus Coronavirus replication CXCL10 cytidylic acid double-stranded expand fibroblast Gene Expression HCoV-229E HCoV-NL63 help Human human coronavirus human coronaviruses human lung IFN IFNs IFNβ in vitro increase in inducer Infection inhibit innate immune interferons ISG15 limit MERS-CoV Nanoparticles Pathogens Poly I:C. post infection PROTECT provided required SARS-CoV-2 SARS-CoV-2 pandemic stimulate translated Treatment Type I IFN type I interferon virus production were infected while [DOI] 10.1016/j.virusres.2022.198925 PMC 바로가기
Pulsed-Xenon Ultraviolet Light Highly Inactivates Human Coronaviruses on Solid Surfaces, Particularly SARS-CoV-2Article Published on 2022-10-232023-07-10 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), [키워드] coronavirus HCoV-229E MERS-CoV pulsed-xenon ultraviolet SARS-CoV-2 virus inactivation [DOI] 10.3390/ijerph192113780 PMC 바로가기
Seasonality of Common Human Coronaviruses, United States, 2014-20211Article Published on 2022-10-012022-11-15 Journal: Emerging Infectious Diseases [Category] 치료기술, [키워드] 2019 novel coronavirus disease acute respiratory syndrome Alpha alphacoronavirus annual variation applied Betacoronavirus Better can be used common coronavirus coronavirus disease Coronaviruses COVID-19 defined enteric expected HCoV-229E HCoV-HKU1 HCoV-NL63 Human human coronavirus Mild Novel coronavirus occurred offset parameter predominant respiratory respiratory infections retrospective SARS-CoV-2 seasonal seasonality seasons severe acute respiratory syndrome coronavirus 2 System the United State United States upper respiratory viruses with COVID-19 zoonoses [DOI] 10.3201/eid2810.220396 PMC 바로가기