healthy subjects – Communicable Diseases Research

Antibody response after COVID-19 vaccination in intravenous immunoglobulin-treated immune neuropathies

Article

Published on 2022-11-012022-11-15
Journal: European journal of neurology [Category] SARS, 진단,

Exploratory analysis of interleukin-38 in hospitalized COVID-19 patients

Article

Published on 2022-11-012022-11-15
Journal: Immunity, Inflammation and Disease [Category] SARS, 바이오마커,

[키워드] Adaptive immune response Admission age Analysis anti-inflammatory effect anti-inflammatory properties binding Biomarker cartilage CD244 CHL1 circulating Clinical data Cohort cohorts Concentration concentrations coronavirus disease correlated correlation COVID-19 COVID-19 patient COVID-19 severity disease dismutase dysregulated enzyme-linked immunosorbent exploratory fatty healthy control healthy controls healthy subjects hospital Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients IL-1 Immunoglobulin in viral increase in infections Inflammatory biomarker intensive care interleukin-38 investigated men moderate Mortality no difference outcome plasma positive correlation positively correlated progression Protein proximity extension assay recent receptor reduce retrieved retrospective cohort study SARS-CoV-2 SERPINA12 severity shown subjects thrombocyte TNF TNFRSF9 validation cohort were measured while women
[DOI] 10.1002/iid3.712 PMC 바로가기

A systematic review and meta-analysis of immune response against first and second doses of SARS-CoV-2 vaccines in adult patients with hematological malignancies

혈액암이 있는 성인 환자의 SARS-CoV-2 백신 1차 및 2차 접종에 대한 면역 반응의 체계적인 검토 및 메타 분석

Review

Published on 2022-09-012022-09-11
Journal: International immunopharmacology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

[키워드] 95% confidence interval 95%CI affected affecting anti-CD20 therapy antibody Antibody detection Antibody Response article booster dose booster doses calculated Cancer patients chronic lymphocytic leukemia CLL Complete conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines develop Diagnosis disease doses evaluate first dose Google Google Scholar healthy subject healthy subjects Hematological malignancies Hematological malignancy higher risk highlight highlighting immune response Immunity immunization Immunocompromised immunogenicity immunosuppressive IMPROVE kinase inhibitors less leukemia lowest Lymphocytic leukemia lymphoma malignancy measure Meta-analysis mRNA mRNA-1273 Myeloma Patient Primary outcome response rate SARS-CoV-2 SARS-CoV-2 vaccine second dose secondary outcome Secondary outcomes seropositive Seropositivity severe coronavirus disease solid tumor solid tumors status subgroup subtype systematic review the disease the vaccine tumors tyrosine tyrosine kinase inhibitor tyrosine kinase inhibitors Vaccine vaccine dose vaccine's immunogenicity Web of Science
[DOI] 10.1016/j.intimp.2022.109046 PMC 바로가기 [Article Type] Review

Retinal microvascular morphology versus COVID-19: What to anticipate?

Research article

Published on 2022-09-012022-10-05
Journal: Photodiagnosis and photodynamic therapy [Category] COVID19(2023년), SARS, 바이오마커, 변종,

High Monocyte Count Associated with Human Cytomegalovirus Replication In Vivo and Glucocorticoid Therapy May Be a Hallmark of Disease

Article

Published on 2022-08-242022-11-16
Journal: International Journal of Molecular Sciences [Category] 치료기술,

[키워드] caused CD14 Characteristics clinical model/translational medicine clinical response Clinical symptoms CMV comparable correlated corticosteroid therapy count COVID-19 cytomegalovirus cytomegalovirus (CMV) kinetics decrease defined definitions of cytomegalovirus disease described Dexamethasone disease dose glucocorticoid growth hallmark healthy subjects homogeneous homogeneous sample of subjects logarithmic phase of infection Human Increased Infection Infectious disease innate immune innate immune response investigated leukopenia lymphopenia macrophages molecular monocyte monocytes characteristics and analysis monocytosis mononucleosis neutropenia observation onset of fever pathogen detection Patient prodrome Replication Sample Significant steroid subject syndrome tested the median viral infection Viral load viral replication Viremia virome virus virus replication
[DOI] 10.3390/ijms23179595 PMC 바로가기

Plasma metabolome and cytokine profile reveal glycylproline modulating antibody fading in convalescent COVID-19 patients

혈장 대사체 및 사이토카인 프로필은 회복기 COVID-19 환자에서 글리실프롤린 조절 항체 퇴색을 나타냅니다

Article

Published on 2022-08-232022-09-11
Journal: Proceedings of the National Academy of Sciences of [Category] SARS, 바이오마커, 진단,

[키워드] accumulated Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alteration antibody association catalyzed cleavage conducted convalescent convalescent COVID-19 patient convalescent COVID-19 patients convalescent patient Convalescent patients coronavirus COVID-19 COVID-19 convalescent patients COVID-19 pandemic cytokine cytokine profile cytokine profiling Cytokines demonstrated dipeptide dipeptidyl peptidase Dipeptidyl peptidase 4 domain down-regulate DPP4 experiment feature Feature selection glycylproline healthy healthy subjects IL-12p40 immune response immune responses individual inhibitor inhibitory effect Inhibitory effects M-CSF machine-learning mechanism metabolite metabolites metabolome metabolomics mice modulating neutralizing antibody outcome peptide plasma Plasma cytokine product public health Quantitative respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination severe acute respiratory syndrome Coronavirus sitagliptin suppresse therapeutic Treatment vaccination Vaccination strategy with COVID-19
[DOI] 10.1073/pnas.2117089119 PMC 바로가기 [Article Type] Article

Ongoing Mycophenolate Treatment Impairs Anti-SARS-CoV-2 Vaccination Response in Patients Affected by Chronic Inflammatory Autoimmune Diseases or Liver Transplantation Recipients: Results of the RIVALSA Prospective Cohort

진행중인 미코페놀레이트 치료는 만성 염증성 자가면역 질환 또는 간 이식 수혜자의 영향을 받는 환자에서 항-SARS-CoV-2 백신 반응을 손상시킵니다: RIVALSA 예상 코호트의 결과

Observational Study

Published on 2022-08-122022-09-11
Journal: Viruses [Category] SARS, 임상, 진단, 치료기술,

[키워드] 95% CI administration Analysis anti-SARS-CoV-2 anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG anti-SARS-CoV-2 vaccination Antibody Response Antibody titers ARMS Arthritis Autoimmune Autoimmune disease Autoimmune diseases Autoimmune hepatitis calcineurin calcineurin inhibitors chronic cohort of patients Complete connective tissue disease Connective tissue diseases detectable develop Diagnosis dose dose reduction Effect effective Eligible patients enrolled evaluate evaluated example first dose healthy subjects hepatology identify IgG immunogenicity immunosuppressive immunosuppressive therapy Immunosuppressive treatment independent predictor independent predictors individual inhibitor liver liver transplant Liver transplantation MMF mRNA COVID-19 vaccine mRNA COVID-19 vaccines mRNA vaccine mRNA-based Multivariate analysis mycophenolate mycophenolate. neoplasia Novara observational study organ other diseases overlapped Patient patients performed predictor Prevent Prospective prospective observational study receiving recipients rejection required response Result rheumatoid arthritis rheumatological SARS-COV-2 infection selected Seroconversion seroconversion failure spondyloarthritis subgroups of patient suffered Suspension Tertiary therapy transplantation transplants treated Treatment unit Univariate analysis university vaccinated individual vaccination Vaccine vaccine response Vasculitis
[DOI] 10.3390/v14081766 PMC 바로가기 [Article Type] Observational Study

Evaluation of serological response to anti-SARS-CoV-2 mRNA vaccination in hematological patients

혈액학적 환자에서 anti-SARS-CoV-2 mRNA 백신접종에 대한 혈청학적 반응 평가

Article

Published on 2022-08-082022-09-12
Journal: Frontiers in Immunology [Category] SARS, 진단,

[키워드] Administered anti-SARS-CoV-2 anti-SARS-CoV-2 IgG anti-SARS-CoV-2 vaccination Anti-spike anti-Spike IgG anti-spike IgG level antibody Antibody titer association Cell Cohort cohort of patient Concentration control arm control group Cutoff demographic variable difference drug Effect evaluated greater health worker healthy healthy subjects hematological Hematological malignancies Hematological malignancy heterogeneous highest identify IgG IgG titer immune system immunoassay Immunocompromised patients Immunosuppression implication inhibitor Italy leukemia Microparticle molecular mRNA mRNA vaccination mRNA vaccine onco-hematology. parameter pathology Patient patients performed Predictive reached reduced reported SARS-CoV-2 SARS-CoV-2 antibody second dose seroconversion rate serological response shown significantly lower spike IgG statistical significance steroid stratified Surveillance the mean the patient Therapies therapy treated tyrosine underlying disease vaccination Vaccine was reduced
[DOI] 10.3389/fimmu.2022.892331 PMC 바로가기 [Article Type] Article

Plasmatic renin-angiotensin system in normotensive and hypertensive patients hospitalized with COVID-19

Research article

Published on 2022-08-012022-10-05
Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] 바이오마커, 치료기술,

[키워드] ACE ACE2 ACE2 expression ACE2 protein acute respiratory syndrome Analysis Ang II angiotensin Angiotensin receptor blockers Angiotensin-converting enzyme angiotensin-converting enzyme 2 angiotensin-converting enzyme inhibitors blockade cause circulating control group coronavirus COVID-19 COVID-19 group COVID-19 patient COVID-19 patients enzymatic activity etiological agent healthy healthy subjects Hospitalized hypertension hypertensive hypertensive patient investigated medications normotensive not different Patient patients protein level RAS receptor remained renin-angiotensin system reported Result significantly Support treated Treatment were excluded were measured with COVID-19
[DOI] 10.1016/j.biopha.2022.113201 [Article Type] Research article

Evaluation of individual and combined NLR, LMR and CLR ratio for prognosis disease severity and outcomes in patients with COVID-19

COVID-19 환자의 질병 중증도 및 결과에 대한 개별 및 결합된 NLR, LMR 및 CLR 비율 평가

Article

Published on 2022-08-012022-09-11
Journal: International immunopharmacology [Category] 바이오마커, 진단, 치료기술,

[키워드] Analysis C-reactive protein characterized CLR Combination Combined Combined markers COVID-19 COVID-19 cases COVID-19 disease COVID-19 patients Critically ill Deceased develop disease disease severity Efficacy healthy controls healthy subject healthy subjects Hospital admission Hospitalization ICU ill patient immunological parameter IMPROVE independent Inflammatory intensive care unit lymphocyte marker material Mild moderate Mortality multivariate logistic regression multivariate logistic regression analysis neutrophil neutrophil/lymphocyte ratio NLR non-ICU normal value outcome parameter pathology Patient patients with COVID-19 performed Peripheral blood Predictive Prognosis Prognostic factor Prominent resulting returned ROC SARS-CoV-2 severe disease Severe infection severity of COVID-19
[DOI] 10.1016/j.intimp.2022.108781 PMC 바로가기 [Article Type] Article