NLRC5 senses NAD + depletion to form a PANoptosome driving PANoptosis and inflammationArticle Published on 2024-06-122024-09-05 Journal: Cell [Category] update2024, [키워드] Apoptosis ASC caspase caspase-1 caspase-3 caspase-7 caspase-8 Colitis creatinine DAMP DSS gasdermin D gasdermin E heme Hemolysis hemophagocytic lymphohistiocytosis Inflammasome Inflammation Inflammatory cell death LPS MLKL necroptosis nicotinamide adenine dinucleotide NLRC5 NLRP12 NLRP3 Pam3CSK4 PAMP PANoptosis PANoptosome Phenylhydrazine poly(I:C) pyroptosis RIPK3 ROS TLR2 TLR4 TLRs TNF [DOI] 10.1016/j.cell.2024.05.034 PMC 바로가기 [Article Type] Article
New N-Terminal Fatty-Acid-Modified Melittin Analogs with Potent Biological ActivityArticle Published on 2024-01-102024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] antimicrobial activity Hemolysis melittin N-terminal fatty acid conjugation proteolytic stability [DOI] 10.3390/ijms25020867 PMC 바로가기 [Article Type] Article
Reduced splenic function can mimic artemisinin resistance in severe malariaArticle Published on 2023-12-282024-08-29 Journal: Journal of Travel Medicine [Category] 말라리아, [키워드] Anaemia Hemolysis hyposplenism Inflammation malaria spleen
The choline-binding proteins PspA, PspC, and LytA of Streptococcus pneumoniae and their interaction with human endothelial and red blood cells스트렙토코쿠스 뉴모니아의 콜린 결합 단백질 PspA, PspC 및 LytA와 이들의 인간 내피세포 및 적혈구와의 상호작용Article Published on 2023-09-082024-07-28 Journal: Infection and Immunity [Category] 폐렴구균 감염증, [키워드] Biofilms cell wall endothelial Hemolysis hemolytic uremic syndrome immune evasion [DOI] 10.1128/iai.00154-23 PMC 바로가기
Coagulation and hemolysis complications in neonatal ECLS: Role of devicesReview Published on 2022-12-012023-06-23 Journal: Seminars in fetal & neonatal medicine [Category] 신종인플루엔자, [키워드] extracorporeal life support Hemolysis Neonatal oxygenator pump thrombosis [DOI] 10.1016/j.siny.2022.101405 [Article Type] Review
Cold agglutinin anti-I antibodies in two patients with COVID-19Article Published on 2022-09-012022-11-15 Journal: Journal of Clinical Laboratory Analysis [Category] 진단, [키워드] abnormality anti-I antibody antibody CAS clinical presentation Cold Agglutinin coronavirus disease COVID-19 COVID-19 case COVID-19 patient diagnosed Diseases Hemolysis hemolytic anemia increase lymphoproliferative diseases Mycoplasma pneumoniae pathophysiology Patient patients with COVID-19 Peripheral blood RBCs red blood cell red blood cells reported required risk risk factor severe COVID-19 syndrome thrombosis Two patient [DOI] 10.1002/jcla.24629 PMC 바로가기
Hyperhemolysis in a patient with sickle cell disease and recent SARS-CoV-2 infection, with complex auto- and alloantibody work-up, successfully treated with tocilizumab복합 자가항체 및 동종항체 검사가 포함된 겸상적혈구병 및 최근 SARS-CoV-2 감염 환자의 과용혈, 토실리주맙으로 성공적으로 치료Case Reports Published on 2022-07-012022-09-12 Journal: Transfusion [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] AIHA/drug-induced IHA antibody appear approved auto autoantibody Blood Cell characterized Chest complex concerning COVID-19 discharged disease Donor Evidence hemoglobin Hemolysis hospital Hospitalization immunohematology (RBC serology, blood groups) incompatible Inflammation lab Patient patients RBC RBCs Red cell returned SARS-COV-2 infection SCD serology single dose Symptom syndrome Tocilizumab transfused transfusion complications-non-infectious. treated Treatment treatment for COVID-19 warm [DOI] 10.1111/trf.16932 PMC 바로가기 [Article Type] Case Reports
The significance of antiglobulin (Coombs) test reactivity in patients with COVID-19COVID-19 환자에서 항글로불린(Coombs) 검사 반응성의 중요성Article Published on 2022-07-012022-09-12 Journal: Immunobiology [Category] COVID19(2023년), MERS, SARS, 신약개발, 진단, [키워드] alteration Analysis Anemia Antiglobulin Antiglobulin (Coombs) test association autoantibody Autoimmune binding CAD Case report characterized Clinical finding complement system activation conducted COVID-19 COVID-19 patients Critical CRP cytokine D-dimer demonstrated described disease disease severity Erythrocytapheresis etiology Evidence examined hemoglobin Hemoglobinopathy Hemolysis hemolytic anemia hospitalized COVID-19 patient hyperinflammation ICU admission indirect bilirubin Laboratory lactate dehydrogenase mechanism metabolites pathophysiological Patient patients with COVID-19 peripheral smear positive RBC RBCs reactive reactivity red blood cell Retrospective study SARS-CoV-2 SARS-CoV-2 protein severity of COVID-19 statistically significant Symptom tested therapy treated Treatment understanding Univariate analysis worsening [DOI] 10.1016/j.imbio.2022.152240 PMC 바로가기 [Article Type] Article
Hemolysis induced by SARS-CoV-2 mRNA vaccination in patients with paroxysmal nocturnal hemoglobinuriaArticle Published on 2022-07-012023-07-09 Journal: International journal of hematology [Category] COVID19(2023년), [키워드] Complement inhibitor Hemolysis mRNA vaccine PNH SARS-CoV-2 [DOI] 10.1007/s12185-022-03387-9 PMC 바로가기
Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open-label studyClinical Trial Published on 2022-06-012022-10-05 Journal: American journal of hematology [Category] 임상, [키워드] Administered AEs antibody approved Autoimmune B-cell lymphoma baseline Blood Cell common adverse event COVID-19 database declined diarrhea disease Dizziness double-blind Europe evaluated fatigue fostamatinib hemoglobin Hemolysis hemolytic anemia Hgb hypertension Immune thrombocytopenia increase inhibitor Insomnia lactate dehydrogenase median multicenter Open-label Patient performed Phase 2 Phase 2 study phase 3 study primary endpoint Randomized rheumatoid arthritis Safety assessment spleen sustained the primary endpoint the United State therapeutic option therapy Treatment tyrosine warm [DOI] 10.1002/ajh.26508 PMC 바로가기 [Article Type] Clinical Trial