Mutations in Genes Encoding Subunits of the RNA Exosome as a Potential Novel Cause of Thrombotic MicroangiopathyCase Report Published on 2024-07-112024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] hemolytic uremic syndrome RNA exosome thrombotic microangiopathy [DOI] 10.3390/ijms25147604 PMC 바로가기 [Article Type] Case Report
How We Interpret Thrombosis with Thrombocytopenia Syndrome?Review Published on 2024-05-012024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] antiphospholipid antibody syndrome Disseminated intravascular coagulation hemolytic uremic syndrome heparin-induced thrombocytopenia paroxysmal nocturnal hemoglobinuria Thrombosis with thrombocytopenia syndrome thrombotic microangiopathy Thrombotic thrombocytopenic purpura vaccine-induced immune thrombotic thrombocytopenia [DOI] 10.3390/ijms25094956 PMC 바로가기 [Article Type] Review
Thrombotic microangiopathies after kidney transplantation in modern era: nosology based on chronologyarticle Published on 2023-09-202024-09-02 Journal: BMC Nephrology [Category] 대상포진, [키워드] hemolytic uremic syndrome Infection Kidney transplantation Malignant hypertension outcomes [DOI] 10.1186/s12882-023-03326-8 PMC 바로가기 [Article Type] article
The choline-binding proteins PspA, PspC, and LytA of Streptococcus pneumoniae and their interaction with human endothelial and red blood cells스트렙토코쿠스 뉴모니아의 콜린 결합 단백질 PspA, PspC 및 LytA와 이들의 인간 내피세포 및 적혈구와의 상호작용Article Published on 2023-09-082024-07-28 Journal: Infection and Immunity [Category] 폐렴구균 감염증, [키워드] Biofilms cell wall endothelial Hemolysis hemolytic uremic syndrome immune evasion [DOI] 10.1128/iai.00154-23 PMC 바로가기
Complement-Mediated Thrombotic Microangiopathy Related to COVID-19 or SARS-CoV-2 Vaccinationarticle Published on 2023-05-222024-09-05 Journal: Kidney International Reports [Category] update2024, [키워드] COVID-19 genetic renal disease hemolytic uremic syndrome SARS-CoV-2 thrombotic microangiopathy vaccination [DOI] 10.1016/j.ekir.2023.05.010 PMC 바로가기 [Article Type] article
Pathology findings in pediatric patients with COVID-19 and kidney dysfunctionArticle Published on 2022-10-012023-07-08 Journal: Pediatric Nephrology (Berlin, Germany) [Category] COVID19(2023년), [키워드] Acute kidney injury AKI COVID-19 Glomerulonephritis hemolytic uremic syndrome Henoch-Schönlein Purpura HSP HUS IgA Vasculitis Kidney biopsy kidney dysfunction nephrotic syndrome Proteinuria Renal pathology SARS-CoV-2 thrombotic microangiopathy TMA [DOI] 10.1007/s00467-022-05457-w PMC 바로가기
Anti-factor H antibody associated hemolytic uremic syndrome following SARS-CoV-2 infectionSARS-CoV-2 감염 후 항인자 H 항체 관련 용혈성 요독 증후군Case Reports Published on 2022-09-012022-09-11 Journal: Pediatric Nephrology (Berlin, Germany) [Category] MERS, SARS, 진단, 치료기술, [키워드] Abnormalities Abstract Alternative complement pathway antibody Atypical autoantibody CFHR1 Chain Reaction complement Complement factor H related protein consecutive patient Coronavirus 19 cut-off Cyclophosphamide dialysis disease episode of estimated glomerular filtration rate Factor Factor H febrile illness filtration rate Follow-up Genetic Genetic studies glomerular filtration rate hemolytic uremic syndrome homozygous Increased information initial management median median titer mycophenolate mycophenolate mofetil New one patient pandemic Pathogenesis Patient patients plasma plasma exchanges polymerase chain polymerase chain reaction Prednisolone ranged required respiratory respiratory symptom respiratory symptoms reverse transcriptase Reverse transcriptase polymerase chain reaction RT-PCR SARS-CoV-2 SARS-COV-2 infection screened serology Specific thrombotic microangiopathy transcriptase Trigger triggered uremic syndrome [DOI] 10.1007/s00467-021-05390-4 PMC 바로가기 [Article Type] Case Reports
C5a and C5aR1 are key drivers of microvascular platelet aggregation in clinical entities spanning from aHUS to COVID-19C5a 및 C5aR1은 aHUS에서 COVID-19에 이르는 임상 기관에서 미세혈관 혈소판 응집의 주요 동인입니다Article Published on 2022-01-082022-09-11 Journal: Blood advances [Category] SARS, 유전자 메커니즘, [키워드] Activation acute respiratory syndrome added aggregation Alternative pathway antithrombogenic Atypical Bacterial infection Bacterial infections binding blockade C5a C5aR1 C5b-9 caused CCX168 Cell chronic inflammatory diseases clinical entity clinical implications Comorbidities Comorbidity complement complement system coronavirus COVID-19 Critical demonstrated develop driver dysfunction dysregulation Effect endothelial endothelial cells Endothelial dysfunction Endothelium Ex vivo Exocytosis Genetic hemolytic uremic syndrome highlight human serum Hyperactivation Infection Inflammatory diseases Microvascular thrombosis normal human serum P-selectin pathogenic mechanisms Patient patients treated Platelet platelet adhesion prothrombotic RalA rare disease Registered selectin serum severe acute respiratory syndrome Coronavirus severe COVID-19 severely ill patients suffered thrombosis Thrombus thrombus formation translate Trial triggered uremic syndrome viral infections von Willebrand factor [DOI] 10.1182/bloodadvances.2021005246 PMC 바로가기 [Article Type] Article
Complement Mediated Hemolytic Anemias in the COVID-19 Era: Case Series and Review of the LiteratureImmunology Published on 2021-11-252022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Activation Atypical Autoimmune autoimmune hemolytic anemia benefit CAD carried clinically Cold agglutinin disease complement Complement inhibitor complex Complication condition COVID-19 COVID-19 disease COVID-19 infection COVID19 vaccine disease dose greater Hemodialysis hemolytic hemolytic anemia hemolytic uremic syndrome include Infection inhibitor Laboratory LDH literature manuscript Mediated occur occurred Occurrence paroxysmal nocturnal hemoglobinuria pathophysiologic Patient Patient education patient population plasma Platelet Prophylaxis provided recognize required review Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine Sery severity steroid subject therapeutic intervention Thrombotic complications Treatment Trigger uremic syndrome Vaccine warm [DOI] 10.3389/fimmu.2021.791429 PMC 바로가기 [Article Type] Immunology
Complement activation in children with Streptococcus pneumoniae associated hemolytic uremic syndrome폐렴구균 관련 용혈성 요독 증후군이 있는 아동에서의 보체 활성화Brief Report Published on 2021-02-042024-07-30 Journal: Pediatric Nephrology (Berlin, Germany) [Category] 폐렴구균 감염증, [키워드] children complement eculizumab hemolytic uremic syndrome Streptococcus pneumonia [DOI] 10.1007/s00467-021-04952-w PMC 바로가기 [Article Type] Brief Report