Molecular Pathogenesis of Ischemic and Hemorrhagic Strokes: Background and Therapeutic ApproachesReview Published on 2024-06-072024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] Hemorrhagic Ischemic Long non-coding RNAs MicroRNAs pathophysiology stroke stroke therapeutics [DOI] 10.3390/ijms25126297 PMC 바로가기 [Article Type] Review
Randomized, double-blind, placebo-controlled, crossover trial of oral doxycycline for epistaxis in hereditary hemorrhagic telangiectasiaArticle Published on 2022-11-072022-11-16 Journal: Orphanet Journal of Rare Diseases [Category] 유전자 메커니즘, [키워드] Analysis Angiogenesis assigned Biomarkers bleeding Blood center double-blind doxycycline Effectiveness ENG Epistaxis Frequency heart failure help hemorrhage Hemorrhagic Hereditary Hereditary hemorrhagic telangiectasia Hereditary hemorrhagic telangiectasia. HHT IL-6 Inflammatory intravenous limitations Liver disease malformation marker mechanism Michael morbidity no significant difference not significantly different observation pathway Patient Placebo placebo-controlled provided Quality of life Randomized controlled trial Randomly RBC recruited Registered Registration secondary significantly higher stroke telangiectasia therapy Toronto Treatment treatment period Trial VEGF [DOI] 10.1186/s13023-022-02539-8 PMC 바로가기
Crimean-Congo Hemorrhagic Fever Outbreak in Refugee Settlement during COVID-19 Pandemic, Uganda, April 2021Article Published on 2022-11-012022-11-15 Journal: Emerging Infectious Diseases [Category] 진단, 치료기술, [키워드] approach Bunyavirales coronavirus coronavirus disease COVID-19 Crimean-Congo hemorrhagic fever Fever Hemorrhagic highlight Human IgG investigation outbreak Outbreak investigation refugee Uganda viral hemorrhagic fever viruses zoonoses zoonotic [DOI] 10.3201/eid2811.220365 PMC 바로가기
Detection of SARS-CoV-2 in a dog with hemorrhagic diarrheaArticle Published on 2022-10-122022-11-15 Journal: BMC veterinary research [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome Affect African amino acid substitution analyzed Asymptomatic B.1.177 Bacterial Cell Ceuta characteristic circulation coronavirus COVID-19 detection diarrhea disease dog Dog COVID-19 excluded fecal gastrointestinal tract Genome Hemorrhagic Highland human SARS-CoV-2 human-to-animal transmission Ile402Val S protein substitution Infection Interaction intrinsic knowledge mapped microbial Microbiome MOST negative test Next-generation sequencing NGS North one health pandemic Pathogens pathology positive presenting RBD Receptor binding domain reported RT-PCR test S protein SARS-CoV-2 SARS-CoV-2 genome sequence Sequencing Spain Spanish suffered Terrier the S protein the spike protein USA variant viral loads viral variant virus West zoonosis [DOI] 10.1186/s12917-022-03453-8 PMC 바로가기
Propofol infusion syndrome & COVID-19 in a victim of multiple gunshot wounds: Diagnostic and therapeutic dilemmasCase report Published on 2022-10-012022-10-05 Journal: Trauma Case Reports [Category] 진단, [키워드] affected Anomaly center Clinical finding condition Contusion COVID COVID-19 Diagnosis differential diagnoses global pandemic gunshot wound Hemorrhagic hypoxia imaging infusion intubation Laboratory lung male more difficult Non-traumatic shock in trauma patients pandemic pathology Patient PCR pharyngeal Pneumonia positive propofol Propofol infusion syndrome retained returned Right upper lobe SARS-CoV-2 Sedation Shock suggested Symptom symptomatic syndrome therapeutic transferred trauma patients worsening [DOI] 10.1016/j.tcr.2022.100687 [Article Type] Case report
A case of acquired hemophilia A and bullous pemphigoid following SARS-CoV-2 mRNA vaccinationArticle Published on 2022-09-012022-11-15 Journal: Journal of the Formosan Medical Association = Taiw [Category] SARS, 진단, [키워드] Acquired acquired hemophilia Acquired hemophilia A activated AHA autoantibody Autoimmunity bleeding Blister bullous bullous pemphigoid Characteristics Diagnosis environmental factor epithelial FVIII Genetic hemophilia Hemorrhagic high mortality rate immune tolerance inhibitor Isolated membrane Moderna mRNA mRNA vaccination mRNA vaccine pathophysiology pemphigoid rare disease recent reported resulting SARS-CoV-2 supported vaccination zone [DOI] 10.1016/j.jfma.2022.02.017 PMC 바로가기
Brain dural arteriovenous fistulas in the COVID-19 Era: A warning and rationale for associationResearch article Published on 2022-09-012022-10-05 Journal: Clinical neurology and neurosurgery [Category] 바이오마커, 변종, 진단, [키워드] age Artery association average Brain dural arteriovenous fistula cardiovascular risk factors cerebral Cerebral venous thrombosis Clinical features Cohort conducted connection correlation COVID-19 COVID-19 infection COVID-19 vaccine diagnosed dural sinus thrombosis Hemorrhagic incidence increase in interval males Neurovascular not different objective Pathogenesis pathogenic Patient post-COVID-19 vaccination prevaccination prothrombotic radiological raise Research Result retrospective risk factor Sex significant increase significantly higher thrombotic treated vaccination Vaccine Vaccines Vascular venous Warning with COVID-19 [DOI] 10.1016/j.clineuro.2022.107367 [Article Type] Research article
SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19코로나19 사망자의 SARS-CoV-2 뇌 부위 검출, 조직병리학, 유전자 발현 및 면역조절 변화Article Published on 2022-08-162022-09-11 Journal: Journal of neuropathology and experimental neurolo [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] Amygdala arising Autopsies Autopsy Blood Brain brains cerebellar cortex change Control COVID-19 COVID-19 cases cytokine Deafferentation detection Differentially expressed genes downregulation Encephalitis fraction Gene Expression Genes Hemorrhagic hemorrhagic encephalitis Histopathology immune immune response indicated involved marker microglia mucosa neuronal Non-COVID-19 olfactory olfactory bulb portal receptor reduced reduction Region Regional RNA polymerase RNA sequence RNA sequences RNA-dependent RNA polymerase RNAseq RT-PCR S gene SARS-CoV-2 SARS-CoV-2 E gene sequence serum Significant subject upregulation viral sequence virus with COVID-19 [DOI] 10.1093/jnen/nlac056 PMC 바로가기 [Article Type] Article
Thromboembolic events in COVID-19 ambulatory patients: An observational study about incidence, and thromboprophylaxis outcomesObservational Study Published on 2022-08-042022-10-05 Journal: PLoS ONE [Category] 임상, [키워드] age ambulatory patients Cohort Complication complications conducted COVID-19 defined described eight event FIVE Hemorrhagic hemorrhagic event high risk incidence LMWH management occurred outcome Patient prophylactic strategy rivaroxaban thromboembolic complication Thromboprophylaxis venous venous thromboembolic [DOI] 10.1371/journal.pone.0270195 PMC 바로가기 [Article Type] Observational Study
Neurological Complications of Dengue Fever뎅기열의 신경학적 합병증Review Published on 2022-08-012022-09-12 Journal: Current neurology and neuroscience reports [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Acute disseminated encephalomyelitis antibody Antibody-dependent enhancement Autoimmune blood vessel cause Cell Central nervous system characterized CNS Coagulopathy Complication Course cranial cytokine release Dengue Dengue fever Dengue hemorrhagic fever Dengue shock syndrome dengue virus described develop Diagnosis differential diagnosis dysregulated Encephalitis Encephalopathy Epidemiology febrile hemorrhages Hemorrhagic Hemorrhagic Stroke Immune-mediated imperative implicated include increasingly infect Infection Inflammatory Injury Involvement Ischemic Isolated manifestation mechanism molecular nervous system Neural neurological Neurological complication Neurological complications of dengue. neuromuscular weakness neurotropic nuclei occur ocular paralysis Pathogenesis Patient plasma Posterior recent renal resulting SARS-CoV2 infection screened serotype Shock syndrome the disease treated Vasculitis virus [DOI] 10.1007/s11910-022-01213-7 PMC 바로가기 [Article Type] Review