Hepatitis A Virus Infection in Cynomolgus Monkeys Confounds the Safety Evaluation of a Drug CandidateOriginal Article Published on 2024-03-192024-09-05 Journal: International Journal of Toxicology [Category] update2024, [키워드] cynomolgus monkey Drug development hepatic pathology hepatitis A virus hepatotoxicity non-human primate safety evaluation toxicology [DOI] 10.1177/10915818241237992 PMC 바로가기 [Article Type] Original Article
Protective Effects of Propolis and Chitosan Nanoparticles against Ibuprofen-Induced Hepatotoxicity in Albino RatsArticle Published on 2024-02-282024-09-05 Journal: Diseases [Category] update2024, [키워드] Anti-inflammatory anti-oxidative Chitosan nanoparticles hepatotoxicity non-steroid anti-inflammatory drugs Propolis [DOI] 10.3390/diseases12030049 PMC 바로가기 [Article Type] Article
Anti-hepatitis C antibody carriage and risk of liver impairment in rural-Cameroon: adapting the control of hepatocellular carcinoma for resource-limited settingsarticle Published on 2023-12-132024-09-05 Journal: BMC Infectious Diseases [Category] update2024, [키워드] ASAT/ALAT Cameroon Hepatitis C virus antibodies (HCVAb) hepatotoxicity Liver impariment [DOI] 10.1186/s12879-023-08880-y PMC 바로가기 [Article Type] article
Liver transaminase concentrations in children with acute SARS-CoV-2 infectionShort Communication Published on 2023-05-302024-09-05 Journal: Clinical biochemistry [Category] update2024, [키워드] Aminotransferase COVID-19 hepatotoxicity liver transaminase pediatric SARS-CoV-2 [DOI] 10.1016/j.clinbiochem.2023.110588 PMC 바로가기 [Article Type] Short Communication
Risk of drug-induced liver injury in chronic hepatitis B and tuberculosis co-infection: A systematic review and meta-analysisMeta-Analysis Published on 2022-12-012023-06-12 Journal: Journal of viral hepatitis [Category] B형 간염, [키워드] DILI Hepatitis B virus hepatotoxicity systematic review Tuberculosis [DOI] 10.1111/jvh.13751 [Article Type] Meta-Analysis
Acute hepatitis in a paediatric patient: immune-mediated drug-induced liver injury or albendazole-induced autoimmune hepatitis?Case Reports Published on 2022-10-312023-06-01 Journal: Journal of infection in developing countries [Category] A형 간염, [키워드] albendazole Autoimmune hepatitis cholestasis hepatotoxicity immune-mediated. [DOI] 10.3855/jidc.16594 [Article Type] Case Reports
Successful liver transplantation for hepatitis B-related acute liver failure in a patient with active COVID-19활성 COVID-19 환자의 B형 간염 관련 급성 간부전에 대한 성공적인 간 이식Case Reports Published on 2022-08-012022-09-11 Journal: Transplant infectious disease : an official journa [Category] B형 간염, COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute COVID-19 acute liver failure Administered anti-spike antibodies anti-spike antibody Antiviral antiviral therapy benefit can not candidate competing complex coronavirus coronavirus disease COVID-19 detectable Deterioration effective Evidence evidence of female Hepatitis hepatitis B hepatotoxicity highlight hospital discharge liver liver failure Liver function liver transplant Liver transplantation management Mild monoclonal antibody nasopharyngeal omicron Patient paucity of data PCR potential risk presenting progression recipient SARS-CoV-2 secondary to significantly the patient Transplant transplantation while with COVID-19 [DOI] 10.1111/tid.13889 PMC 바로가기 [Article Type] Case Reports
In Silico Virtual Screening of Marine Aldehyde Derivatives from Seaweeds against SARS-CoV-2SARS-CoV-2에 대한 해조류의 해양 알데히드 유도체의 실리코 가상 스크리닝Article Published on 2022-06-162022-09-11 Journal: Marine Drugs [Category] COVID19(2023년), SARS, 치료제, [키워드] 3-hydroxybenzaldehyde 3,4-dihydroxybenzaldehyde 4-hydroxybenzaldehyde 6LU7 Absorption acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition aldehyde aldehyde derivatives Algorithm Analysis analyzed binding energy caused clinical trials Compound Computer simulation coronavirus coronavirus disease Coronavirus disease 2019 derivative derivatives disease distribution docking excretion exhibited global pandemic Health hepatotoxicity hydroxybenzaldehyde in silico indicated inhibitor Interaction metabolism molecular docking non-toxic outbreak PDB predicted protease Protein Data Bank protocol SARS-CoV-2 Screening seaweed severe acute respiratory syndrome Coronavirus therapeutic compound Therapeutic compounds these compound these compounds Toxicity Virtual screening [DOI] 10.3390/md20060399 PMC 바로가기 [Article Type] Article
Hepatotoxicity associated with PD-1 blockade antibodies in cancer patients co-infected with hepatitis B virusArticle Published on 2022-05-012023-06-12 Journal: Cancer immunology, immunotherapy : CII [Category] B형 간염, [키워드] Cancer, Hepatitis B virus hepatotoxicity Immunotherapy PD-1 Safety [DOI] 10.1007/s00262-021-03082-4
In silico analysis of the interactions of certain flavonoids with the receptor-binding domain of 2019 novel coronavirus and cellular proteases and their pharmacokinetic properties특정 플라보노이드와 2019년 신종 코로나바이러스 수용체 결합 도메인의 상호작용 및 세포성 프로테아제 및 이들의 약동학적 특성에 대한 실리코 분석Article Published on 2022-04-012022-09-11 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 치료제, [키워드] 2019 2019 novel coronavirus 2019-nCoV acute respiratory syndrome coronavirus Analysis binding blood-brain barrier cathepsin B caused cellular protease cellular proteases Compound conducted coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 death drug-likeness eukaryotic cells evaluated FIVE flavonoid flavonoids gallate glycoprotein hepatotoxicity hydrogen Hydrogen bond inhibit Interaction interactions microorganism MM/PBSA molecular molecular docking molecular dynamics Molecular mechanics nCoV P-glycoprotein pharmacokinetic Protein Proteins RBD Receptor binding domain respiratory SARS-CoV-2 Serine serine protease severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike glycoprotein subgroup substrate supported surface area target proteins the receptor-binding domain TMPRSS2 Toxicity transmembrane serine protease transmembrane serine protease 2 Van [DOI] 10.1080/07391102.2020.1840444 PMC 바로가기 [Article Type] Article