heterologous expression – Communicable Diseases Research

RelCoVax®, a two antigen subunit protein vaccine candidate against SARS-CoV-2 induces strong immune responses in mice

SARS-CoV-2에 대한 2개의 항원 소단위 단백질 백신 후보인 RelCoVax®는 마우스에서 강력한 면역 반응을 유도합니다

Article

Published on 2022-07-302022-09-11
Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법,

[키워드] adjuvant adjuvants Administered alum aluminum aluminum hydroxide Antibody titer Antibody titers Antigen antigen exposure Cell Cellular immune response cellular immune responses Combination contribute COVID-19 pandemic CpG Delta delta variant demonstrated develop dominant dose regimen dual E. coli effective vaccine elicited Emergency use authorization evade evidenced glycoprotein heterologous expression hydroxide IFN-γ immune responses immunize immunized immunized mice in vitro induce mammalian cell mammalian cells mice Mutation N protein N proteins neutralize Neutralizing antibodies neutralizing antibody nucleocapsid prime and boost Protein RBD Receptor binding domain Region RelCoVax® S protein Safe SARS-CoV-2 SARS-CoV-2 viral SARS-CoV-2 virus serum splenocyte splenocytes stimulated strain strong immune response subunit Subunit vaccine Th1 the SARS-CoV-2 virus vaccinated individuals Vaccine vaccine candidate vaccine candidates variants of SARS-CoV-2 viral strains virus entry
[DOI] 10.1016/j.vaccine.2022.06.026 PMC 바로가기 [Article Type] Article

Bomidin: An Optimized Antimicrobial Peptide With Broad Antiviral Activity Against Enveloped Viruses

Bomidin: 외피 바이러스에 대한 광범위한 항바이러스 활성을 가진 최적화된 항균 펩티드

Article

Published on 2022-05-192022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료제,

[키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Against AMP AMPs antibiotic antimicrobial antimicrobial peptide antimicrobial peptide. antimicrobial peptides AVP Bacteria Bacterial bovine Chikungunya Chikungunya virus CHIKV Coronavirus-2 Defense Dengue dengue virus DENV-2 disrupt Escherichia coli Evolution expressed expression extraction front line fungi global public health herpes simplex herpes simplex virus heterologous expression HSV-2 life-threatening lipids mechanism membrane membranes methionine molecular offer organism overcome pathogen Pathogens peptide peptides produced purification Research SARS-CoV-2 sequence Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus therapeutic variety virus viruses
[DOI] 10.3389/fimmu.2022.851642 PMC 바로가기 [Article Type] Article

The Nuts and Bolts of SARS-CoV-2 Spike Receptor-Binding Domain Heterologous Expression

SARS-COV-2 스파이크 수용체 결합 도메인 이종 발현의 견과류 및 볼트

Article

Published on 2021-12-022022-09-01
Journal: Biomolecules [Category] SARS, 유전자 메커니즘, 진단,

A Comprehensive Overview on the Production of Vaccines in Plant-Based Expression Systems and the Scope of Plant Biotechnology to Combat against SARS-CoV-2 Virus Pandemics

Review

Published on 2021-06-152022-10-28
Journal: Plants [Category] COVID-19,

SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target

SARS-CoV-2 외피 단백질은 급성 호흡곤란 증후군(ARDS)과 유사한 병리학적 손상을 유발하고 항바이러스 표적을 구성합니다.

Article

Published on 2021-06-102022-09-11
Journal: Cell Research [Category] MERS, SARS, 바이오마커, 변종, 유전자 메커니즘, 진단, 치료제,

[키워드] activity acute respiratory distress acute respiratory distress syndrome administration angiotensin Anti-SARS-CoV-2 Activity antiviral target ARDS cation channels cause caused Cell cell death cell types channel inhibitor chemokine chemokines cytokine Cytokine storm Cytokines damages death dominant negative drug target exhibited expressing heterologous expression human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 in vitro in vivo infected cells Inflammation inhibitor Intravenous administration lung Lungs macrophages membranes mice Molecular biology multi-organ failure Mutation positively correlated Prophylactic Protective Protein purified reduced respiratory distress robust SARS-CoV-2 SARS-CoV-2 envelope SARS-CoV-2-infected cells secretion spleen Support susceptible cell syndrome the SARS-CoV-2 therapeutic transgenic mice Viral Viral load
[DOI] 10.1038/s41422-021-00519-4 PMC 바로가기 [Article Type] Article

Endophytes: the novel sources for plant terpenoid biosynthesis

Endophytes: 식물 테르페노이드 생합성을 위한 새로운 소스

Review

Published on 2021-06-012022-09-11
Journal: Applied Microbiology and Biotechnology [Category] SARS, 유전자 메커니즘,

Soluble expression, rapid purification, biological identification of chicken interferon-alpha using a thioredoxin fusion system in E. coli and its antiviral effects to H9N2 avian influenza virus

Article

Published on 2019-01-012023-06-22
Journal: Preparative biochemistry & biotechnology [Category] 조류인플루엔자,

[키워드] Avian influenza virus chicken interferon-α heterologous expression Recombinant protein thioredoxin fusion system.
[DOI] 10.1080/10826068.2019.1566150

Vaccines to prevent severe acute respiratory syndrome coronavirus-induced disease

Article

Published on 2007-04-092022-11-01
Journal: Virus research [Category] Coronavirus, MERS,