A novel method to monitor COVID-19 fatality rate in real-time, a key metric to guide public health policyArticle Published on 2022-10-312022-11-16 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] applied approach changes in COVID-19 Delta driven by early phase Effect Epidemic Epidemics epidemiological data Fatality rate fused Germany high accuracy Infection MONITOR omicron pandemic public health required sensitivity vaccination Vaccine variant [DOI] 10.1038/s41598-022-23138-4 PMC 바로가기
DeepLPI: a novel deep learning-based model for protein-ligand interaction prediction for drug repurposingArticle Published on 2022-10-282022-11-16 Journal: Scientific Reports [Category] 신약개발, [키워드] applied approved drug baseline CNN computational method COVID-19 dataset Davis downloaded drug-target interaction drugs Features high accuracy Interaction memory molecular patients predict protein-ligand interaction Research sequence target protein target protein sequence vector [DOI] 10.1038/s41598-022-23014-1 PMC 바로가기
An explainable model of host genetic interactions linked to COVID-19 severityArticle Published on 2022-10-262022-11-16 Journal: Communications Biology [Category] 변종, 유전자 메커니즘, [키워드] age and gender Analysis classifiers Cohort contributing to covariates COVID-19 COVID-19 severity dataset Factor Features Follow-up Genetic GWAS high accuracy highest Host identify immune pathways immune system increased risk Inflammatory Interaction Italian patients MCC molecular mechanism offer outcome Patient phenotypic predict predicted Predictive screened several variant Severe COVID-19 Infection severity Signaling significantly Stratification stratified Support tested therapeutic intervention Thoracic variant viral infection WES with COVID-19 [DOI] 10.1038/s42003-022-04073-6 PMC 바로가기
Cov2clusters: genomic clustering of SARS-CoV-2 sequencesArticle Published on 2022-10-192022-11-16 Journal: BMC Genomics [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Accuracy advance approach bioinformatics Canada Cluster Clustering Combination COVID-19 pandemic epidemiological data epidemiologically Evidence genomic Genomic analysis global public health high accuracy High-resolution identify identifying increase in management mimicking pandemic pathogen Phylogenetic Phylogenetic tree produced producing Public public health Repository SARS-CoV-2 SARS-CoV-2 sequence SARS-CoV-2 sequence data sequence sequencing technology stability Surveillance the disease Transmission viral pathogen WGS whole genome sequence Whole genome sequencing [DOI] 10.1186/s12864-022-08936-4 PMC 바로가기
Recent Advances of Representative Optical Biosensors for Rapid and Sensitive Diagnostics of SARS-CoV-2Article Published on 2022-10-122022-11-15 Journal: Biosensors [Category] COVID19(2023년), SARS, 치료기술, [키워드] advance biosensor Corona COVID-19 Diagnosis diagnostic diagnostics disadvantage enhancement equipment explained high accuracy IMPROVE infected patients inherent limit operator optical optical biosensors outbreak pandemic Plasmon point-of-care point-of-care diagnostics polymerase chain Rapid recent required Research resonance reverse transcription RT-PCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 vaccines sensitive sensitivity Sensitivity and specificity SPR surface time-consuming virus [DOI] 10.3390/bios12100862 PMC 바로가기
Knowledge, attitudes, and practices toward COVID-19: A cross-sectional study during normal management of the epidemic in ChinaArticle Published on 2022-09-082022-11-15 Journal: Frontiers in Public Health [Category] 진단, [키워드] acute viral infection Administered affected analysis of variance Attitude average China Chinese COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 vaccine cross-sectional demographic characteristics Descriptive statistics Epidemic high accuracy IMPROVE KAP knowledge Logistic regression management measure Measures online survey participant positive attitude practices Prevent preventive measures promote public health question recruited Stage statistical analysis Symptoms symptoms of COVID-19 the epidemic total score Transmission were used [DOI] 10.3389/fpubh.2022.913478 PMC 바로가기
COVID salivary diagnostics: A comparative technical studyCOVID 타액 진단: 비교 기술 연구Article Published on 2022-09-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 assumption can be used Care Chain Reaction coronavirus coronavirus disease Coronavirus disease 2019 COVID COVID-19 Delta diagnostic diagnostics direct methods eliminating envelope golden standard heat heat-released RNA high accuracy indicate individuals infected individual infected individuals Intervention Isolation mass mass surveillance molecular molecular diagnostics Mouthwash nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs noninvasive NPs Open reading frame open reading frame 1 open reading frame 1ab ORF1ab pandemic patients polymerase chain polymerase chain reaction promote remained reported respiratory restriction RNA RNA extraction robust RT-PCR Saliva salivary sampling SARS-CoV-2 sensitivity severe acute respiratory syndrome Coronavirus specificity Surveillance the patient Viral viral gene viral genes virus spread while widespread [DOI] 10.1002/jmv.27883 PMC 바로가기 [Article Type] Article
Biomarkers selection for population normalization in SARS-CoV-2 wastewater-based epidemiologyArticle Published on 2022-09-012022-11-15 Journal: Water research [Category] SARS, 바이오마커, [키워드] 5-hydroxyindoleacetic acid acute respiratory syndrome addition approach Biomarker Biomarkers CDC changes in city Community complement Concentration contributing to coronavirus coronavirus disease correlation COVID-19 creatinine Critical demonstrated Dilution distribution epidemiological Epidemiology evaluated FIVE help high accuracy investigated Local metabolite Mild normalized outbreak Paraxanthine plant Population Population biomarker Population normalization Prevalence reported SARS-CoV-2 SARS-CoV2 selected significantly tested the SARS-CoV-2 Treatment utility Variability Viral load viral loads virus Volume Wastewater-based epidemiology [DOI] 10.1016/j.watres.2022.118985 PMC 바로가기
A non-invasive ultrasensitive diagnostic approach for COVID-19 infection using salivary label-free SERS fingerprinting and artificial intelligenceResearch article Published on 2022-09-012022-10-05 Journal: Journal of photochemistry and photobiology. B, Bio [Category] SARS, 바이오마커, 변종, 진단, 치료기술, [키워드] Accuracy approach artificial intelligence biochemical change Classifier clinical COVID-19 COVID-19 infected patient COVID-19 infection COVID-19 outbreak demonstrated Diagnosis diagnostic diagnostics Efficiency false-negative genetic diversity global healthcare gold standard healthy healthy control high accuracy invasive Label-free limit Machine learning algorithms management MERS-CoV Mutation Nasopharyngeal swab Non-invasive Patient Population screening positive predicted reagents risk Saliva salivary SARS-CoV SARS-CoV-2 SARS-COV-2 infection scattering sensitivity specificity Stage subjects Support surface enhanced Raman spectroscopy SVM the patient virus virus spike protein [DOI] 10.1016/j.jphotobiol.2022.112545 [Article Type] Research article
Combining metabolome and clinical indicators with machine learning provides some promising diagnostic markers to precisely detect smear-positive/negative pulmonary tuberculosis대사체와 임상 지표를 기계 학습과 결합하면 도말 양성/음성 폐결핵을 정확하게 감지하는 몇 가지 유망한 진단 마커를 제공합니다.Article Published on 2022-08-252022-09-11 Journal: BMC Infectious Diseases [Category] Coronavirus, 바이오마커, 치료기술, [키워드] Amino acid Analysis best Biomarker Biomarkers cause Characteristics Combination conducted Control controls COVID-19 death death case death cases detect Diagnosis diagnostic diagnostic biomarker Diagnostic biomarkers discriminant analysis dysfunction enriched pathways fatty Fatty acid feature global pandemic high accuracy Infectious disease machine machine learning marker metabolisms metabolite metabolome metabolomic metabolomic analysis metabolomic profiling metabolomics Mycobacterium tuberculosis Mycobacterium tuberculosis (Mtb) offer Patient patients performed plasma Precision provide pulmonary tuberculosis R package random Random forest Seven significant enrichment smear Smear-positive/negative pulmonary tuberculosis Support SVM TB patient three group three groups Tuberculosis Tuberculosis (TB) was performed [DOI] 10.1186/s12879-022-07694-8 PMC 바로가기 [Article Type] Article