SARS-CoV-2 Virus Culture, Genomic and Subgenomic RNA Load, and Rapid Antigen Test in Experimentally Infected Syrian HamstersArticle Published on 2022-09-282022-11-16 Journal: Journal of Virology [Category] SARS, 유전자 메커니즘, [키워드] Antigen benefit characterized Contact tracing correlated COVID-19 COVID-19 patients Culture determine genomic genomic and subgenomic RNA genomic RNA gRNA hamster hamsters high correlation highlight Isolation load Nasal washes oropharyngeal swabs predicted Rapid rapid antigen test RNA RT-PCR SARS-CoV-2 sgRNA Syrian hamsters Test threshold viral culture virus [DOI] 10.1128/jvi.01034-22 PMC 바로가기
Clinical factors affecting depression in patients with painful temporomandibular disorders during the COVID-19 pandemic Research Published on 2022-08-292022-10-05 Journal: Scientific Reports [Category] 치료법, [키워드] Affect affecting aggravate Anxiety arthralgia assessment axis BAI Beck clinical clinical factors COVID-19 COVID-19 pandemic Depression diagnosed disorder Factor Factors female females high correlation increase in intensity inventory investigated moderate multifactorial Multiple regression analysis myalgia negatively affected Novel coronavirus Pain pandemic Patient physical positively correlated Psychological Psychological distress recent Sex significantly significantly increased Stress stress level temporomandibular disorder TMD TMD pain was recorded [DOI] 10.1038/s41598-022-18745-0 [Article Type] Research
Humoral immune response characterization of heterologous prime-boost vaccination with CoronaVac and BNT162b2CoronaVac 및 BNT162b2를 사용한 이종 프라임-부스트 백신 접종의 체액 면역 반응 특성화Article Published on 2022-08-192022-09-12 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome ADCC ADCP Analysis anti-RBD anti-RBD IgG antibody antibody Antibody binding assays baseline binding domain binding kinetics BNT162b2 booster Cohort CoronaVac coronavirus decrease dose elapsed enrolled evaluated Fc-mediated function Fc-mediated functions Follow-up General population healthy individual Heterologous heterologous prime-boost heterologous vaccination high correlation humoral immune response IgG antibody IgG level immune immune response increase in individual Interaction mechanisms Neutralization assay Participants Prevent Prospective Study RBD RBD-ACE2 remained reporter SARS-CoV-2 SARS-COV-2 infection Seroconversion serological seronegative serum severe infections significantly to define vaccination vaccination schedule Vaccine [DOI] 10.1016/j.vaccine.2022.07.023 PMC 바로가기 [Article Type] Article
A fast online questionnaire for screening mental illness symptoms during the COVID-19 pandemic Research Published on 2022-08-042022-10-05 Journal: Translational Psychiatry [Category] 치료법, [키워드] Analysis Anxiety applied caused characteristic Clinical practice COVID-19 COVID-19 pandemic criterion demonstrated Depression disorder Effect Efficiency evaluate explained Factor GLA healthy controls high correlation identify illness Mental mental health mental illness mental symptom Patient PCA Prevalence principal component analysis questionnaire reliability Research Result ROC Screen Symptom Symptoms Validity [DOI] 10.1038/s41398-022-02086-7 [Article Type] Research
Development of flow cytometry-based assays to assess the ability of antibodies to bind to SARS-CoV-2-infected and spike-transfected cells and mediate NK cell degranulationSARS-CoV-2 감염 및 스파이크 형질감염 세포에 결합하고 NK 세포 탈과립을 매개하는 항체의 능력을 평가하기 위한 유세포 분석 기반 분석법 개발Article Published on 2022-06-012022-09-11 Journal: Cytometry. Part A : the journal of the Internation [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제, [키워드] antibody Antibody binding Antibody Response Antibody responses Antibody titer Antibody titers assays binding capture Cell cells Clinical studies correlation COVID-19 degranulation demonstrated detect determine develop development Dilution dilution sery Efficiency effort elicited facilitate function functional antibody response healthy control high correlation Immunity IMPROVE infected cell infected cell. infected cells infected individuals magnitude moderate NK cell NK cell degranulation outcome overlap pandemic plasma platform ranged reduce response response rates responses SARS-CoV-2 SARS-CoV-2 disease SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2-infected cell SARS-CoV-2-infected cells SARS-CoV-2-infected individual SARS-CoV-2-infected individuals Spearman the SARS-CoV-2 transfected cells Undetermined vaccination [DOI] 10.1002/cyto.a.24552 PMC 바로가기 [Article Type] Article
Application of the SARS-CoV-2-S1 ACE-2 receptor interaction as the basis of the fully automated assay to detect neutralizing SARS-CoV-2-S1 antibodies in blood samples혈액 샘플에서 중화 SARS-CoV-2-S1 항체를 검출하기 위한 완전 자동화 분석의 기초로서 SARS-CoV-2-S1 ACE-2 수용체 상호작용의 적용Article Published on 2022-05-012022-09-11 Journal: Journal of Immunological Methods [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] ACE-2 receptor ACE-2 receptor binding inhibition assay anti-SARS-CoV-2 anti-SARS-CoV-2 antibody antibody Antibody titer Antibody titers application automated binding blood sample Blood samples BNT162b2 Concentration Control convalescent patient Convalescent patients detect determine Diagnostic method EliA high correlation Interaction large cohort mRNA mRNA-1273 neutralization test Neutralizing Neutralizing antibodies neutralizing antibody neutralizing antibody titers Phadia plaque reduction neutralization PRNT provide quantified Quantitative SARS-CoV-2 SARS-CoV-2 S1 protein Sensitivity and specificity [DOI] 10.1016/j.jim.2022.113258 PMC 바로가기 [Article Type] Article
Rapid Quantitative Point-Of-Care Diagnostic Test for Post COVID-19 Vaccination Antibody Monitoring코로나19 백신 접종 후 항체 모니터링을 위한 신속한 정량적 현장 진료 진단 테스트Article Published on 2022-04-272022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] agreement analyzed Antibody Response Antibody responses Antibody Units assays binding antibody unit capillary blood chemiluminescence CLIA CLIA analyzer correlation correlation coefficient COVID-19 COVID-19 pandemic demonstrated diagnostic DiaSorin evaluate evaluated expressed high correlation IgG immune response immune responses immunoassay immunomagnetic agglutination assay individual Infection Laboratory laboratory assays lateral flow LIAISON monitoring performed plasma plasma sample plasma samples POC POC test point-of-care quantification Quantitative Rapid rapid IgG-IgM-IgA combined test Result S protein S protein trimer S1/S2 SARS-CoV-2 SARS-CoV-2 IgM SARS-CoV-2 spike SARS-CoV-2 spike protein sensitivity Serological testing serology test Spearman Spike protein Support Test Total total antibodies total antibody Trimeric spike protein vaccination venous were measured Whole blood [DOI] 10.1128/spectrum.00396-22 PMC 바로가기 [Article Type] Article
Fluorescent bioassay for SARS-CoV-2 detection using polypyrene-g-poly(ε-caprolactone) prepared by simultaneous photoinduced step-growth and ring-opening polymerizations동시 광유도 단계 성장 및 개환 중합에 의해 제조된 폴리피렌-g-폴리(ε-카프로락톤)를 사용한 SARS-CoV-2 검출을 위한 형광 생물검정Article Published on 2022-04-262022-09-11 Journal: Mikrochimica Acta [Category] COVID19(2023년), SARS, 치료기술, [키워드] Analysis approach calibrated characterized coefficient Coefficient of variation construction demonstrated described Diagnosis feature Fluorescence fluorescence intensity fluorescent Fluorescent biosensor Graft Graft copolymer high correlation immunofluorescence limit of detection Nasopharyngeal samples negative and positive Photopolymerization platform pyrene quantification repeatability reporter reproducibility Ring-opening polymerization RT-PCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody Significant significant differences spectral analysis Step-growth polymerization. Variation was tested was used [DOI] 10.1007/s00604-022-05244-2 PMC 바로가기 [Article Type] Article
Long-Term Antibody Response and Vaccination Efficacy in Patients with COVID-19: A Single Center One-Year Prospective Study from the Czech RepublicCOVID-19 환자의 장기 항체 반응 및 예방 접종 효능: 체코의 단일 센터 1년 전향적 연구Article Published on 2022-03-042022-09-11 Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, [키워드] Admission analyzed antibody Antibody Response Antibody responses antigen detection center characterized Cohort courses COVID-19 patient COVID-19 patients Czech Republic diagnosis of SARS-CoV-2 diagnostic disease Dynamics ELISA enrolled Evidence high correlation hospitalized patient hospitalized patients IgA IgG IgG antibodies IgG antibody IgG level IgG levels IgM and IgG indicated Infection Laboratory neutralization test Patient PCR performed positive positive antibody response positive antibody responses Prospective Prospective Study Reinfection response Sample SARS-CoV-2 SARS-COV-2 infection sensitivity serological data serology significantly specific antibodies specific antibody sustained the SARS-CoV-2 vaccination Virus neutralization virus neutralization test VNT [DOI] 10.3390/v14030526 PMC 바로가기 [Article Type] Article
Direct comparison of Xpert Xpress, FilmArray Respiratory Panel, Lumipulse antigen test, and RT-qPCR in 165 nasopharyngeal swabs165 Nasopharyngeal Swabs에서 Xpert Xpress, FilmArray 호흡기 패널, Lumipulse 항원 검사 및 RT-QPCR의 직접 비교Research Article Published on 2022-03-042022-09-10 Journal: BMC Infectious Diseases [Category] MERS, SARS, 치료기술, [키워드] 95% CI 95% confidence interval Antigen approved automated COVID-19 Ct values diagnostic test diagnostic tests Direct except for exhibited FilmArray high correlation less Lumipulse NAAT Nasopharyngeal swab nasopharyngeal swabs nucleic acid nucleic acid amplification nucleic acid amplification test offer Panel positive Quantitative random random access respiratory Result RT-qPCR RT-qPCR assays SARS-CoV-2 sensitivity specificity Viral Viral load viral loads Xpert Xpress [DOI] 10.1186/s12879-022-07185-w PMC 바로가기 [Article Type] Research Article