Poxvirus MVA Expressing SARS-CoV-2 S Protein Induces Robust Immunity and Protects Rhesus Macaques From SARS-CoV-2SARS-CoV-2 S 단백질을 발현하는 폭스바이러스 MVA는 강력한 면역을 유도하고 SARS-CoV-2로부터 붉은털원숭이를 보호합니다Article Published on 2022-03-162022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 변종, 진단, [키워드] BAL Bronchoalveolar lavage caused Cell clinical trials Computed tomography COVID-19 COVID-19 pandemic cytokine Cytokine storm domain effective vaccine Effective vaccines Efficacy elicited expressing favor Fever full-length SARS-CoV-2 histological histological examination IFNγ IgG antibodies IgG antibody IL-4 immunogenic immunogenicity lung Lung pathology Lungs macaque macaques modified vaccinia virus MVA vaccine nasal mucosa Neutralizing antibodies neutralizing antibody novel Protein Receptor-binding domain reduced reduction rhesus rhesus macaque rhesus macaques robust Safe Safety SARS-CoV-2 SARS-CoV-2 S several variant several variants spike tomography vaccination Vaccine virus load [DOI] 10.3389/fimmu.2022.845887 PMC 바로가기 [Article Type] Article
Synchronous “skip” facial metastases from colorectal adenocarcinoma: a case report and review of literature결장 직장 선암종의 동기식 "건너 뛰기"안면 전이 : 사례 보고서 및 문헌 검토Review Published on 2022-02-162022-09-10 Journal: BMC Gastroenterology [Category] 치료기술, [키워드] abdomen abdominal pain abdominal wall absence adenocarcinoma affected Case report Chest clinical suspicion Colon Colonoscopy Colorectal cancer Colorectal surgery Complete condition COVID-19 pandemic CT scan described diarrhoea dissemination evaluated excisional biopsy facial Facial lesions histological histological examination laparoscopic left hemicolectomy Left hemicolectomy lesion lesions liver Local lung Lungs male Mask medical history nodule palpable mass Patient patient reported performed perineum Physical examination poorly differentiated postoperative recurrence Seven sigmoid colon signet ring cell skin Skin metastasis Spread stenosis synchronous Tumor venous [DOI] 10.1186/s12876-022-02141-z PMC 바로가기 [Article Type] Review
The Tissue Distribution of SARS-CoV-2 in Transgenic Mice With Inducible Ubiquitous Expression of hACE2Molecular Biosciences Published on 2022-01-182022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] ACE2 Activation alteration Brain Brain tissues change clinically COVID-19 COVID-19 pathogenesis Cre recombinase Day death distribution examined expressing expression hACE2 hACE2 switch-on mice histological examination human ACE2 induce Infection infections internal organ intestine intranasal intranasal infection Isolation Laboratory lung Lungs mice Mild murine model novel coronavirus disease offspring prevented provide resulting Safe SARS-CoV-2 SARS-COV-2 infection strain Tamoxifen tissue transgene transgenic mice treated Treatment Viral load virus weighed weight loss [DOI] 10.3389/fmolb.2021.821506 PMC 바로가기 [Article Type] Molecular Biosciences
Assessment of adjuvantation strategy of lipid squalene nanoparticles for enhancing the immunogenicity of a SARS-CoV-2 spike subunit protein against COVID-19코로나19에 대한 SARS-CoV-2 스파이크 소단위 단백질의 면역원성을 향상시키기 위한 지질 스쿠알렌 나노입자의 면역보강 전략 평가Article Published on 2021-09-252022-09-12 Journal: International journal of pharmaceutics [Category] MERS, SARS, 진단, [키워드] Administered aluminum assessment comparable coronavirus disease COVID-19 COVID-19 vaccine cytokine dose effective intervention Efficacy ELISA enhancing the immunogenicity group histological examination IgG IL-10 immune response immunomodulation induce information injection interferon intramuscularly investigated Lipid Lipid squalene nanoparticles mice modulating Neutralizing pandemic Protective antibody Protein S-protein SARS-CoV-2 spike secretion serum sample significantly Single injection splenocytes subunit the SARS-CoV-2 the vaccine Vaccine vaccine adjuvant vaccine injection virus [DOI] 10.1016/j.ijpharm.2021.121024 PMC 바로가기 [Article Type] Article
Roborovski hamster (Phodopus roborovskii) strain SH101 as a systemic infection model of SARS-CoV-2Research Article Published on 2021-09-142022-10-28 Journal: Virulence [Category] COVID-19, SARS, [키워드] Phodopus roborovskii SH101 acute respiratory syndrome animal model animal models Antiviral Brain cause chills clinical manifestation clinical symptom cough COVID-19 COVID-19 animal model COVID-19 cases Dyspnea Evolution Fever histological examination hunched posture Infection initial Laboratory labored breathing liver organ damage Pathogenesis Phodopus Pneumonia Post-infection representing respiratory viruses roborovski hamster ruffled fur SARS-CoV-2 SARS-COV-2 infection shaking Strains Symptom systemic symptoms transmission rate Vaccine weight loss [DOI] 10.1080/21505594.2021.1972201 PMC 바로가기 [Article Type] Research Article
Papulo-purpuric dermatitis of childhood: a distinct PLEVA-like eruption associated to SARS-CoV-2 infection. Clinical, histopathological and immunohistochemical study of 10 cases소아의 구진 자반 피부염: SARS-CoV-2 감염과 관련된 뚜렷한 PLEVA 유사 발진. 10건의 임상, 조직병리학 및 면역조직화학 연구Article Published on 2021-09-012022-09-11 Journal: Pediatric dermatology [Category] SARS, 치료법, [키워드] 2019-nCoV antibody children clinical dermatopathology dermatosis evidence of feature histological examination histopathological Histopathology Italy nucleocapsid pandemic papular papular eruption pediatric PLEVA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic skin histopathology. staining the SARS-CoV-2 Viral protein Viral proteins [DOI] 10.1111/pde.14777 PMC 바로가기 [Article Type] Article
Fetal and placental infection with SARS-CoV-2 in early pregnancy임신 초기 SARS-CoV-2에 의한 태아 및 태반 감염Case Reports Published on 2021-07-012022-09-11 Journal: Journal of medical virology [Category] SARS, 치료법, [키워드] accompanied acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Chain Reaction clinician consequence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection double-stranded RNA dsRNA early pregnancy fetal fetus first trimester histological histological examination Hyperinflammatory immunofluorescence immunohistochemistry in some Infection Inflammation kidney lung management Microscopy miscarriage nucleocapsid protein organ organs outcomes pandemic Particle Particles Placenta placental Placental infection polymerase chain polymerase chain reaction positive Pregnancy pregnant women produced Prominent Protein provided Quantitative Replication responsible reverse transcription RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid SARS-CoV-2 protein severe acute respiratory syndrome Coronavirus target targets tissues Transmission Viral RNA [DOI] 10.1002/jmv.26965 PMC 바로가기 [Article Type] Case Reports
Toxicity and Activity of Ethanolic Leaf Extract of Paullinia pinnata Linn (Sapindaceae) in Shigella flexneri-Induced Diarrhea in Wistar RatsArticle Published on 2020-12-312024-09-07 Journal: J Evid Based Integr Med [Category] 세균성이질, [키워드] Biochemical parameters histological examination infectious diarrhea Paullinia pinnata subacute toxicity. PMC 바로가기
Mechanisms and evidence of vertical transmission of infections in pregnancy including SARS-CoV-2sSARS-CoV-2를 포함한 임신 중 감염의 수직 전파 메커니즘 및 증거Review Published on 2020-12-012022-09-11 Journal: Prenatal diagnosis [Category] SARS, 치료기술, [키워드] ACE-2 amniotic Amniotic fluid Blood breast milk Chain Reaction Child clinical sample clinical samples co-expression concerning Consensus Cord blood COVID-19 cytoplasmic demonstrated determine diagnostic eight entry of SARS-CoV-2 Evidence explain histological examination Infection Inflammation Interaction involved lack membrane Migration mother Neonatal Neonatal COVID-19 pathogen performed Placenta placental placental barrier polymerase chain polymerase chain reaction Pregnancy pregnant women Prevent protective mechanism protective mechanisms question real-time polymerase chain reaction receptor reported SARS-CoV-2 SARS-CoV-2 IgM screened secretion susceptibility Swab tissue TMPRSS2 Transmission transplacental infection Umbilical cord umbilical cord blood Vascular Viral Viral particles with COVID-19 [DOI] 10.1002/pd.5765 PMC 바로가기 [Article Type] Review
Spontaneous pneumothorax as unusual presenting symptom of COVID-19 pneumonia: surgical management and pathological findingsCase Report Published on 2020-10-122022-10-30 Journal: Journal of Cardiothoracic Surgery [Category] Coronavirus, MERS, SARS, [키워드] bleeding Blood Bullectomy Case report Chest COVID-19 COVID-19 patient disease histological examination hospital Infection infiltration initial interstitial interstitial pneumonia ipsilateral lung surgery lymphocyte management microthrombi Novel coronavirus parenchymal pathological finding pathology Patient performed Plasma cells Pneumonia Pneumothorax presenting reported Spontaneous pneumothorax surgical Surgical Procedure Symptom Thoracoscopy tissue treated Treatment Two patient vascular congestion vessel [DOI] 10.1186/s13019-020-01343-4 PMC 바로가기 [Article Type] Case Report