Long Term Assessment of Anti-SARS-CoV-2 Immunogenicity after mRNA Vaccine in Persons Living with HIVArticle Published on 2023-11-222024-09-05 Journal: Vaccines [Category] update2024, [키워드] HIV-1 infection immunity waning mRNA vaccines Neutralizing antibodies SARS-COV-2 infection T cell immunity [DOI] 10.3390/vaccines11121739 PMC 바로가기 [Article Type] Article
The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive-strand RNA virusesArticle Published on 2022-11-072022-11-16 Journal: EMBO Reports [Category] SARS, 변종, [키워드] Antiviral approach cell line complexes CRISPR DDX42 DDX42 DEAD-box RNA helicase Depletion DNA dominant-negative elements expression Helicase HIV-1 HIV-1 infection identify immunoprecipitation in vitro increase Infection inhibit inhibitor Interaction intrinsic intrinsic immunity LINE-1 mutant overexpression Perspective primary cells Replication restrict reverse transcription ribonucleoprotein RNA RNA virus RNA viruses RNA-seq analysis SARS-CoV-2 target cells viral infections viral inhibition viruses [DOI] 10.15252/embr.202154061 PMC 바로가기
Neuropilin-1 in the pathogenesis of preeclampsia, HIV-1, and SARS-CoV-2 infection: A reviewReview Published on 2022-10-022023-07-10 Journal: Virus research [Category] COVID19(2023년), [키워드] HIV-1 infection MicroRNAs Neuropilin-1 preeclampsia SARS-COV-2 infection [DOI] 10.1016/j.virusres.2022.198880 PMC 바로가기 [Article Type] Review
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies Reviews Published on 2022-08-122022-10-05 Journal: Nature reviews. Immunology [Category] 변종, 유전자 메커니즘, 임상, [키워드] acquisition activate B cell complex mechanism Critical effective expand genetic diversity glycoprotein HIV-1 HIV-1 infection immune evasion immune system induce Interaction Lineage mutations neutralizing antibody Research Safe Strategy vaccination Vaccine Vaccine development [DOI] 10.1038/s41577-022-00753-w [Article Type] Reviews
Ultrasensitive detection and quantification of viral nucleic acids with Raindance droplet digital PCR (ddPCR)Raindance droplet 디지털 PCR(ddPCR)을 사용한 바이러스 핵산의 초고감도 검출 및 정량화Article Published on 2022-05-012022-09-11 Journal: Methods (San Diego, Calif.) [Category] COVID19(2023년), SARS, 치료기술, [키워드] animal models Antiretroviral therapy approaches assays caused Cell Combination cure Cure research ddPCR detect Detection sensitivity diagnosis and monitoring digital PCR disease DNA and RNA Efficacy example highlighting HIV HIV prevention HIV-1 HIV-1 infection HIV-1 viral immunodeficiency virus infected individual infected individuals Infection Infectious disease Infectious diseases inhibition inhibitors Interpretation model systems NHP non-human primate nucleic acid Nucleic acid detection nucleic acids outcome platform predictor progression quantification quantitation Raindance reduced required Research reverse transcription rhesus macaque rhesus macaques RNA RT-ddPCR SARS-CoV2 sensitive Simian simian immunodeficiency virus SIV step tissue tissues Treatment treatment intervention treatment interventions viral DNA viral nucleic acid viral nucleic acid detection viral nucleic acids Viral reservoir virus viruses [DOI] 10.1016/j.ymeth.2021.04.025 PMC 바로가기 [Article Type] Article
Prolonged viral suppression with anti-HIV-1 antibody therapy Research Published on 2022-04-132022-10-05 Journal: Nature [Category] 변종, 임상, [키워드] absence administration Affect Analysis antibody ART CD4+ changes in clearance clinical study Combination Concentration decrease dose Drug administration effective Genome HIV-1 HIV-1 infection Immunotherapy individual individuals Infection neutralizing antibody performed Predictive Prolonged provirus public health reached remained required reservoir sensitivity sensitivity analysis serum Seven suppress suppressed the antibody therapy to define Viraemia Virologic suppression virus Volunteer with HIV [DOI] 10.1038/s41586-022-04597-1 [Article Type] Research
Assessment of NKG2C copy number variation in HIV-1 infection susceptibility, and considerations about the potential role of lacking receptors and virus infection Research Published on 2022-03-222022-10-05 Journal: Journal of Human Genetics [Category] 유전자 메커니즘, [키워드] absence activating assessment association Cell cells Clinical features Co-infection coding Cohort Complete controls evaluated expressed expression Frequency function genetic background genotyping HBV HCV healthy blood donors HIV HIV infection HIV-1 HIV-1 infection HIV-infected patient Host Human individuals Infection involved knowledge natural PCR Phenotypes polymorphism protein expression receptor signaling pathway susceptibility triggered Variation virus infection was performed [DOI] 10.1038/s10038-022-01029-w [Article Type] Research
SARS-CoV-2 Evolution and Spike-Specific CD4+ T-Cell Response in Persistent COVID-19 with Severe HIV Immune SuppressionCase Report Published on 2022-01-112022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] acute respiratory syndrome adaptive CD4+ CD4+ T cell response complex Control coronavirus coronavirus disease Course COVID-19 diagnosed Evolution HIV HIV-1 HIV-1 infection HIV-negative IL-2 immunological Immunosuppressed Infection Lineage B.1.1.7 marker Mutation Mycobacterium nasopharyngeal sample outcome persistence persistent Pneumonia polymerase chain reported response reverse transcription RNA SARS-CoV-2 SARS-CoV-2 evolution SARS-COV-2 infection severe COVID-19 suppression T-cell Response variant [DOI] 10.3390/microorganisms10010143 PMC 바로가기 [Article Type] Case Report
Stage II and stage III periodontitis clinical burdens of HIV-1 undergoing antiretroviral therapyOriginal Article Published on 2021-10-032024-09-04 Journal: Clinical Oral Investigations [Category] 대상포진, [키워드] HAART HIV-1 infection Periodontitis [DOI] 10.1007/s00784-021-04201-2 PMC 바로가기 [Article Type] Original Article
The Role of L-Selectin in HIV InfectionReview Published on 2021-09-292023-08-30 Journal: Frontiers in Microbiology [Category] E형 간염, [키워드] ADAM metalloproteinases envelope gp120 HIV-1 infection L-selectin (CD62L) shedding viral entry viral release [DOI] 10.3389/fmicb.2021.725741 PMC 바로가기 [Article Type] Review