HLA association – Communicable Diseases Research

Individualized Constellation of Killer Cell Immunoglobulin-Like Receptors and Cognate HLA Class I Ligands that Controls Natural Killer Cell Antiviral Immunity Predisposes COVID-19

Genetics

Published on 2022-02-222022-10-31
Journal: Frontiers in Genetics [Category] COVID-19,

[키워드] absence activating acute respiratory syndrome anti-SARS-CoV-2 Antiviral antiviral immunity Asymptomatic Biomarker cause Cell characterized class Cognate Combination constellation Control controls coronavirus Coronavirus-2 COVID-19 COVID-19 cohort COVID-19 host genetics COVID-19 patient COVID-19 susceptibility Defense determine detrimental Frequency General population Genetic healthy HLA HLA association HLA class I HLA gene HLA-Bw4 Host Hypothesis individual individuals Infection Inflammatory cytokine KIR KIR receptors KIR-HLA KIR-HLA association KIR2DL2 + KIR2DS1 KIR2DS5 KIR3DL1 KIR3DL2 Ligand ligands majority maturation natural NK cell NK cell function NK cells offer outcome pathologic Patient patients hospitalized receptor reduce regulated responsible SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 susceptibility severe COVID-19 severe COVID-19 patient significantly lower subsequent tested the patient triggered variable with mild disease
[DOI] 10.3389/fgene.2022.845474 PMC 바로가기 [Article Type] Genetics

HLA-DRB1 Alleles Associated with Lower Leishmaniasis Susceptibility Share Common Amino Acid Polymorphisms and Epitope Binding Repertoires

Article

Published on 2021-03-172024-09-02
Journal: Vaccines [Category] 대상포진,

[키워드] Antigen presentation HLA association human leukocyte antigen Immunogenetics immunoinformatics Leishmania Leishmaniasis vaccine candidates
[DOI] 10.3390/vaccines9030270 PMC 바로가기 [Article Type] Article

Tetanus-diphtheria vaccination in adults: the long-term persistence of antibodies is not dependent on polyclonal B-cell activation and the defective response to diphtheria toxoid re-vaccination is associated to HLADRB1∗01

성인에서의 파상풍-디프테리아 백신 접종: 항체의 장기적인 지속성은 다클론 B세포 활성화에 의존하지 않으며, 디프테리아 톡소이드 재접종에 대한 결함 있는 반응은 HLADRB1∗01과 관련이 있다.

Article

Published on 2018-10-292024-08-19
Journal: Vaccine [Category] 파상풍,

[키워드] Anti-toxoid antibodies duration of protection HLA association memory vaccination
[DOI] 10.1016/j.vaccine.2018.09.041

Increased herpes zoster risk associated with poor HLA-A immediate early 62 protein (IE62) affinity

HLA-A 즉각 초기 62 단백질 (IE62) 친화성이 낮을수록 증가하는 대상포진 위험

Article

Published on 2018-06-012023-05-31
Journal: Immunogenetics [Category] 대상포진, 두창, 수두, 홍역,

[키워드] herpes zoster HLA association MHC peptide affinity Varicella zoster virus
[DOI] 10.1007/s00251-017-1047-x

Immunological evasion of immediate-early varicella zoster virus proteins

Article

Published on 2016-07-012023-05-31
Journal: Immunogenetics [Category] 두창, 수두, 홍역,

[키워드] HLA association MHC affinity prediction Varicella zoster virus Viral immune evasion
[DOI] 10.1007/s00251-016-0911-4

Immunological evasion of immediate-early varicella zoster virus proteins

Article

Published on 2016-07-012023-05-31
Journal: Immunogenetics [Category] 두창, 수두, 홍역,

[키워드] HLA association MHC affinity prediction Varicella zoster virus Viral immune evasion
[DOI] 10.1007/s00251-016-0911-4

HLA targeting efficiency correlates with human T-cell response magnitude and with mortality from influenza A infection

Article

Published on 2013-08-132023-06-14
Journal: Proceedings of the National Academy of Sciences of [Category] Fulltext, 신종인플루엔자,

[키워드] HLA association MHC Native American T-cell epitope
[DOI] 10.1073/pnas.1221555110 PMC 바로가기