Development by design of experiment and validation of a HPLC-UV method for simultaneous quantification of 1-nitro-2-phenylethane and methyleugenol: Application to nail permeation/retention studiesArticle Published on 2024-02-282024-08-30 Journal: Journal of Pharmaceutical and Biomedical Analysis [Category] 백선증, [키워드] 1-Nitro-2-phenylethane Design of experiment HPLC Methyleugenol Nail permeation Porcine hoof. PMC 바로가기
A simple and rapid external standard calibration HPLC method for determination of lumefantrine in dried blood spot samples from malaria patients in Botswanaarticle Published on 2024-01-312024-09-01 Journal: Biomedical Chromatography [Category] 말라리아, [키워드] dried blood spot HPLC LLOQ Lumefantrine malaria [Article Type] article
Assessing in vitro stability of remdesivir (GS-5734) and conversion to GS-441524 in feline plasma and whole bloodResearch Article Published on 2024-01-302024-09-05 Journal: The Veterinary Quarterly [Category] update2024, [키워드] cat Feline infectious peritonitis feline microsome FIP GS-441524 GS-5734 HPLC Remdesivir [DOI] 10.1080/01652176.2024.2305731 PMC 바로가기 [Article Type] Research Article
Quantification of GS-441524 concentration in feline plasma using high performance liquid chromatography with fluorescence detectionResearch Article Published on 2023-08-172024-09-05 Journal: The Veterinary Quarterly [Category] update2024, [키워드] cat feline Feline infectious peritonitis FIP GS-441524 HPLC Remdesivir [DOI] 10.1080/01652176.2023.2246553 PMC 바로가기 [Article Type] Research Article
High-performance liquid chromatography with fluorescence detection for mycophenolic acid determination in saliva samplesarticle Published on 2023-03-112024-09-05 Journal: Pharmacological Reports [Category] update2024, [키워드] HPLC mycophenolate mofetil mycophenolic acid nephrotic syndrome Saliva Therapeutic Drug Monitoring [DOI] 10.1007/s43440-023-00474-4 PMC 바로가기 [Article Type] article
Structural interactions of phytoconstituent(s) from cinnamon, bay leaf, oregano, and parsley with SARS-CoV-2 nucleocapsid protein: A comparative assessment for development of potential antiviral nutraceuticalsArticle Published on 2022-10-012022-11-15 Journal: Journal of food biochemistry [Category] COVID19(2023년), SARS, 진단, 치료제, [키워드] affinity Antiviral antiviral agent apigenin binding binding domain binding interaction biological activity C-terminal Cancer Cancer cells candidate carried cell line cell lines cells Cinnamomum cinnamon complex complexes components Compound computational analysis computational approach CTD cytotoxicity death drug candidate Druglikeness effective Efficacy evaluate evaluated examined greater HPLC in silico in vitro in vivo Interaction lack less molecular molecular dynamics MTT N-terminal Naturally NTD nucleocapsid nutraceutical oregano Origanum outcome parsley. plant predicted profile Prophylactic Protein provided Research responsible RNA SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 nucleocapsid protein stability symptomatic targets therapeutic therapeutic drug therapy Toxicity treating COVID-19 Treatment virus was determined was performed worsened [DOI] 10.1111/jfbc.14262 PMC 바로가기
Structures, biomimetic synthesis, and anti-SARS-CoV-2 activity of two pairs of enantiomeric phenylpropanoid-conjugated protoberberine alkaloids from the rhizomes of Corydalis decumbensArticle Published on 2022-09-012022-11-15 Journal: Archives of pharmacal research [Category] SARS, 치료제, [키워드] ACE2 receptor analyses Analysis anti-SARS-CoV-2 Anti-SARS-CoV-2 Activity Antiviral binding Biomimetic synthesis biosynthetic Compound Corydalis Corydalis decumbens COVID-19 ECD exhibited ferulic acid host cells HPLC Isoquinoline alkaloid. Pathways purified SARS-CoV-2 pseudovirus Structure X-ray [DOI] 10.1007/s12272-022-01401-6 PMC 바로가기
Alterations in the molecular composition of COVID-19 patient urine, detected using Raman spectroscopic/computational analysis라만 분광/전산 분석을 사용하여 감지한 COVID-19 환자 소변의 분자 구성 변화Article Published on 2022-07-182022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Abnormalities Accuracy affected alteration Analysis analyzed Bladder cancer Care Chain Reaction Chromatography Clinical pathology collected complex component components computational analysis Contact contact with contributing to correlation correlations COVID-19 COVID-19 disease COVID-19 patient creatinine defined detect determine disease disease severity EGFR elevated fingerprint gas chromatography Gas Chromatography-Mass Spectrometry GC-MS glomerular filtration rate healthy healthy individual healthy individuals Hospitalized HPLC identify in urine include Infection Inflammatory liquid Liquid chromatography Long mass spectrometry metabolomic analysis Mild moderate molecular Negative predictive value pathology Patient patients performance Peritoneal dialysis positive Positive predictive value Predictive value Raman spectroscopy random ranged reaction representing respiratory RT-PCR SARS-CoV-2 virus sensitivity serum creatinine severity specificity specimen specimens Spectrometry Symptom symptomatic tested Urinalysis Urine urine specimens Viral Volunteer with COVID-19 [DOI] 10.1371/journal.pone.0270914 PMC 바로가기 [Article Type] Article
Improved HPLC method for the determination of ribavirin concentration in red blood cells and its application in patients with COVID-19적혈구 내 리바비린 농도 측정을 위한 개선된 HPLC 방법 및 COVID-19 환자에 대한 적용Article Published on 2022-07-012022-09-11 Journal: Biomedical chromatography : BMC [Category] 치료제, [키워드] addition Adverse drug reactions Anemia antiviral drug Blood changes in Concentration correlation coefficient COVID-19 declined determine Efficacy erythrocyte hematocrit hematological parameter hematological parameters hemoglobin HPLC Improved Interim linear lowest Patient patients with COVID-19 phosphatase phosphorylated ranged red blood cell red blood cells ribavirin synthetic the patient [DOI] 10.1002/bmc.5370 PMC 바로가기 [Article Type] Article
Non-glycosylated SARS-CoV-2 RBD elicited a robust neutralizing antibody response in mice글리코실화되지 않은 SARS-CoV-2 RBD는 마우스에서 강력한 중화 항체 반응을 유도했습니다Article Published on 2022-07-012022-09-12 Journal: Journal of Immunological Methods [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] adjuvant Analysis Antibody Response binding activity candidate vaccine CpG Delta domain Efficacy elicited enzyme Escherichia Escherichia coli glycosylated HPLC immune response Inclusion induce mice neutralized Neutralizing activity neutralizing antibody Neutralizing antibody response omicron overexpressed produced protective immunity protective neutralizing antibody Protein provided pseudovirus pseudoviruses purification RBD Receptor-binding domain Receptor-binding domain (RBD) robust SARS-CoV-2 SARS-CoV-2 RBD the RBD Vaccine was obtained wild-type [DOI] 10.1016/j.jim.2022.113279 PMC 바로가기 [Article Type] Article