HSP70 positively regulates translation by interacting with the IRES and stabilizes the viral structural proteins VP1 and VP3 to facilitate duck hepatitis A virus type 1 replicationResearch Article Published on 2024-05-172024-09-05 Journal: Veterinary Research [Category] update2024, [키워드] assembly DHAV-1 Hsp70 IRES translation VP1 VP3 [DOI] 10.1186/s13567-024-01315-9 PMC 바로가기 [Article Type] Research Article
Targeting heat shock proteins 90 and 70: A promising remedy for both autoimmune bullous diseases and COVID-19Review Published on 2022-12-152023-07-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), [키워드] autoimmune bullous disorders (AIBDs) COVID-19 heat shock proteins (HSPs). Hsp70 Hsp90 SARS-CoV-2 [DOI] 10.3389/fimmu.2022.1080786 PMC 바로가기 [Article Type] Review
Rationale for 1068 nm Photobiomodulation Therapy (PBMT) as a Novel, Non-Invasive Treatment for COVID-19 and Other Coronaviruses: Roles of NO and Hsp70Review Published on 2022-05-072023-06-15 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), MERS, SARS, [키워드] 1068 nm COVID-19 Cytoprotection Hsp70 Inflammation nitric oxide Photobiomodulation SARS-CoV-2 thrombosis viral replication [DOI] 10.3390/ijms23095221 PMC 바로가기 [Article Type] Review
Preexisting antibodies targeting SARS-CoV-2 S2 cross-react with commensal gut bacteria and impact COVID-19 vaccine induced immunityArticle Published on 2022-01-012022-11-15 Journal: Gut Microbes [Category] SARS, 진단, [키워드] anti-SARS-CoV-2 antibodies antibody Antibody titer Bacteria binding collected commensal gut bacteria correlated COVID-19 vaccine cross-react cross-reactive cross-reactive antibody demonstrated DNA vaccine domain dominant dose E. coli Efficacy epitope fecal Gut gut bacteria gut microbiota healthy Host Hsp60 Hsp70 Immunity immunized Impact inactivated LC-MS metagenomic sequencing mice microbial monoclonal antibodies monoclonal antibody mounted naïve P144 Protein RBD binding reactive S protein SARS-CoV-2 SARS-CoV-2 S SARS-CoV-2 S2 SARS-CoV-2 vaccination SPF Spike protein Vaccine vaccine immunogenicity variety [DOI] 10.1080/19490976.2022.2117503 PMC 바로가기
Heat shock protein 70 could enhance porcine epidemic diarrhoea virus replication by interacting with membrane proteinsResearch Article Published on 2021-10-302022-10-28 Journal: Veterinary Research [Category] Coronavirus, MERS, [키워드] assays Cell cells cellular complex diarrhoea downregulated early stage ENhance Epidemic expression Heat shock heat shock protein heat shock protein 7 Hsp70 immunofluorescence immunoprecipitation Infection investigated M protein membrane membrane protein MOST overexpression PEDV Porcine epidemic diarrhoea virus Protein protein expression reduction in Replication resulting significantly structural protein virions virus virus replication [DOI] 10.1186/s13567-021-01006-9 PMC 바로가기 [Article Type] Research Article
Identification of a Region in the Common Amino-terminal Domain of Hendra Virus P, V, and W Proteins Responsible for Phase Transition and Amyloid FormationArticle Published on 2021-09-072023-08-29 Journal: Biomolecules [Category] E형 간염, [키워드] amyloids CR binding assays fibrils Hendra virus Hsp70 Intrinsically disordered proteins phase separation and transitions SAXS TEM V protein [DOI] 10.3390/biom11091324 PMC 바로가기 [Article Type] Article
Analysis of allergen components and identification of bioactivity of HSP70 in pollen of Populus deltoidesResearch Published on 2021-09-032023-08-30 Journal: Proteome Science [Category] E형 간염, [키워드] Populus deltoides pollen allergen allergic disease Hsp70 Proteosome [DOI] 10.1186/s12953-021-00178-8 PMC 바로가기 [Article Type] Research
Role of Heat Shock Proteins (HSP70 and HSP90) in Viral InfectionReview Published on 2021-08-292022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, SARS, [키워드] antiviral therapy Bacteria biological significance can be used carried Cell cell differentiation chaperone complex conditions Course current death ENhance eukaryote expression facilitate Factor heat heat shock protein homeostasis Host HSP Hsp70 Hsp90 Hsps immune in some Infection Inflammatory maintain mechanism molecular basis polymerase presenting Protein Proteins responsible role SARS-CoV-2 shown stability stressors survival therapeutic potential transcriptional translational viral gene viral infection Viral protein viral replication virus [DOI] 10.3390/ijms22179366 PMC 바로가기 [Article Type] Review
Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA VirusesArticle Published on 2020-12-102022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Antiviral antiviral activity Antiviral compound Antiviral compounds Antiviral strategies antiviral therapies antivirals approach caused cellular cellular pathway complex coronavirus Ebola virus Effect effort Essential Factor health emergency Hemorrhagic fever virus highlighting host cell Hsp70 identify Interaction knowledge novel outbreak pathogenic pathogenic RNA viruses pathway phenotypic Protein recent RNA RNA virus RNA viruses SARS-CoV-2 small molecule inhibitor target Target identification targeting Treatment Viral proteins viral replication virus Virus-host interactions [DOI] 10.3390/v12121423 PMC 바로가기 [Article Type] Article
Interaction of HSPA5 (Grp78, BIP) with negatively charged phospholipid membranes via oligomerization involving the N-terminal end domainArticle Published on 2020-11-012023-07-12 Journal: Cell stress & chaperones [Category] SARS, [키워드] Charged phospholipids Hsp70 HSPA5 liposomes membranes [DOI] 10.1007/s12192-020-01134-9 PMC 바로가기