A Randomized Controlled Clinical Trial of Nasal Immunization with Live Virulence Attenuated Streptococcus pneumoniae Strains Using Human Infection Challenge인간 감염 도전을 이용한 생균 독성 약화 폐렴구균 균주로의 비강 면역화에 대한 무작위 대조 임상 시험Article Published on 2023-10-152024-08-24 Journal: American Journal of Respiratory and Critical Care Medicine [Category] 폐렴구균 감염증, [키워드] attenuated strains human challenge nasal administration. Streptococcus pneumoniae
Shigella-Specific Immune Profiles Induced after Parenteral Immunization or Oral Challenge with Either Shigella flexneri 2a or Shigella sonnei시겔라 플렉스네리 2a 또는 시겔라 소네이로 경구 도전 또는 비경구 면역화 후 유도된 시겔라 특이 면역 프로파일Article Published on 2021-08-252024-08-22 Journal: mSphere [Category] 세균성이질, [키워드] antibody Correlate of protection Gut-homing responses human challenge Immune profile immunogenicity Shigella
Immune response characterization in a human challenge study with a Shigella flexneri 2a bioconjugate vaccine인간 도전 연구에서 Shigella flexneri 2a 생체접합 백신의 면역 반응 특성화Research Paper Published on 2021-04-012024-07-30 Journal: eBioMedicine [Category] 세균성이질, [키워드] Bioconjugate vaccine Gut-homing responses human challenge immunogenicity Parenteral immunization Shigella [DOI] 10.1016/j.ebiom.2021.103308 PMC 바로가기 [Article Type] Research Paper
Controlled Human Infection to Speed Up SARS-CoV-2 Vaccine DevelopmentSARS-CoV-2 백신 개발을 가속화하기 위한 통제된 인간 감염Immunology Published on 2021-03-122022-08-31 Journal: Frontiers in Immunology [Category] MERS, SARS, 신약개발, [키워드] Controlled controlled human infection (CHI) coronavirus development Ethics Human human challenge SARS-CoV-2 speed Vaccine development [DOI] 10.3389/fimmu.2021.658783 PMC 바로가기 [Article Type] Immunology
Establishment of a Controlled Human Infection Model with a Lyophilized Strain of Shigella sonnei 53GShigella sonnei 53G의 동결 건조 균주를 이용한 통제된 인간 감염 모델 구축Article Published on 2020-09-232024-08-22 Journal: mSphere [Category] 세균성이질, [키워드] Controlled human infection models diarrhea enteric disease human challenge Shigella Shigellosis
Toward a Controlled Human Infection Model of Pertussis백일해의 통제된 인간 감염 모델을 향하여Article Published on 2020-07-112024-08-25 Journal: Clinical infectious diseases : an official publication of the Infectious [Category] 백일해, [키워드] Bordetella pertussis human challenge Immunity Pathogenesis Vaccine
The Ratiometric Transcript Signature MX2/GPR183 Is Consistently Associated With RTS,S-Mediated Protection Against Controlled Human Malaria InfectionMX2/GPR183 비율 전사 서명은 조절된 인간 말라리아 감염에 대한 RTS,S 매개 보호와 일관되게 연관되어 있습니다.Original Research Published on 2020-04-282024-08-11 Journal: Frontiers in immunology [Category] 말라리아, [키워드] clinical immunology human challenge interferon response Malaria vaccines Systems vaccinology vaccine correlates [DOI] 10.3389/fimmu.2020.00669 PMC 바로가기 [Article Type] Original Research
Generating the Evidence for Typhoid Vaccine Introduction: Considerations for Global Disease Burden Estimates and Vaccine Testing Through Human Challenge장티푸스 백신 도입을 위한 증거 생성: 글로벌 질병 부담 추정 및 인간 도전을 통한 백신 테스트에 대한 고려사항Article Published on 2019-11-012024-07-29 Journal: Clinical infectious diseases : an official publication of the Infectious [Category] 살모넬라증, [키워드] Epidemiology human challenge Infectious diseases typhoid Vaccines [DOI] 10.1093/cid/ciz630 PMC 바로가기
Differential Effects of Influenza Virus NA, HA Head, and HA Stalk Antibodies on Peripheral Blood Leukocyte Gene Expression during Human InfectionArticle Published on 2019-05-142023-06-14 Journal: mBio [Category] Fulltext, 신종인플루엔자, [키워드] antibody function Genomics HA head antibodies HA stalk antibodies host response human challenge immune markers immune response Influenza Microarrays NA antibodies regulation of gene expression [DOI] 10.1128/mBio.00760-19 PMC 바로가기
Intestinal Immunity to Poliovirus Following Sequential Trivalent Inactivated Polio Vaccine/Bivalent Oral Polio Vaccine and Trivalent Inactivated Polio Vaccine–only Immunization Schedules: Analysis of an Open-label, Randomized, Controlled Trial in Chilean Infants폴리오바이러스에 대한 장 면역: 순차적인 삼가형 불활성 폴리오 백신/이원성 경구 폴리오 백신 및 삼가형 불활성 폴리오 백신 단독 면역 일정에 따른 분석 - 칠레 유아를 대상으로 한 공개 라벨, 무작위, 대조 시험 분석Article Published on 2018-11-152024-08-01 Journal: Clinical infectious diseases : an official publication of the Infectious [Category] 폴리오, [키워드] human challenge Inactivated vaccine live oral vaccine mucosal immunity Poliovirus [DOI] 10.1093/cid/ciy603 PMC 바로가기