Antimalarial activity assay of artesunate-3-chloro-4(4-chlorophenoxy) aniline in vitro and in mice modelsarticle Published on 2023-04-302024-09-01 Journal: Parasitology Research [Category] 말라리아, [키워드] ADMET profiles antimalaria Artesunate-3-chloro-4-(4-chlorophenoxy) aniline hybrid drugs [Article Type] article
Advancement of chimeric hybrid drugs to cure malaria infection: An overview with special emphasis on endoperoxide pharmacophoresarticle Published on 2021-07-312024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] Antimalarials Artemisinin combination therapy Chimeric bitherapy endoperoxide hybrid drugs [Article Type] article
Anti-COVID drugs: repurposing existing drugs or search for new complex entities, strategies and perspectivesPerspective Published on 2020-07-232022-10-31 Journal: Future Medicinal Chemistry [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Analysis antiviral activity antiviral agent antiviral drugs Bioactivity calculated characteristic complex COVID-19 double hit effect drug drugs effective drug hybrid drugs Modification molecular oleanolic acid parameter Perspective predicted repurposing SARS-CoV-2 selected Spread Structure therapy virus [DOI] 10.4155/fmc-2020-0204 PMC 바로가기 [Article Type] Perspective
Novel antimalarial chloroquine- and primaquine-quinoxaline 1,4-di-N-oxide hybrids: Design, synthesis, Plasmodium life cycle stage profile, and preliminary toxicity studiesarticle Published on 2018-10-312024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] blood stage Chloroquine hybrid drugs liver stage primaquine Quinoxaline 1,4-di-N-Oxide [Article Type] article
From hybrid compounds to targeted drug delivery in antimalarial therapyArticle Published on 2015-08-152024-08-29 Journal: Bioorganic & Medicinal Chemistry [Category] 말라리아, [키워드] drug combination endoperoxide hybrid drugs malaria quinoline resistance Targeted drug delivery
Quinine conjugates and quinine analogues as potential antimalarial agentsarticle Published on 2015-06-302024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] Chloroquine Ferroquine heterocycles hybrid drugs malaria Quinine [Article Type] article
A Fragmenting Hybrid Approach for Targeted Delivery of Multiple Therapeutic Agents to the Malaria Parasite말라리아 기생충에 대한 다중 치료제의 표적 전달을 위한 분열형 하이브리드 접근법Communication Published on 2011-03-072024-08-15 Journal: ChemMedChem [Category] 말라리아, [키워드] Antiparasitic agents drug delivery hybrid drugs malaria prodrugs [DOI] 10.1002/cmdc.201100002 PMC 바로가기 [Article Type] Communication