Characterization of the swarming behavior of Anopheles coluzzii and Anopheles gambiae (Diptera: Culicidae) populations in a hybrid zone of SenegalArticle Published on 2023-11-142024-08-28 Journal: Annals of Medicine and Surgery [Category] 말라리아, [키워드] Anopheles coluzzii Anopheles gambiae hybridization Senegal swarming behavior.
Hybridization Approach Toward Novel Antituberculars: Design, Synthesis, and Biological Evaluation of Compounds Combining Pyrazinamide and 4-Aminosalicylic AcidArticle Published on 2023-01-132023-07-11 Journal: ACS Infectious Diseases [Category] COVID19(2023년), [키워드] 4-aminosalicylic acid hybridization Multidrug resistance pyrazinamide stability Tuberculosis [DOI] 10.1021/acsinfecdis.2c00433
A computational approach to biological pathogenicityArticle Published on 2022-11-012022-11-15 Journal: Molecular genetics and genomics : MGG [Category] 바이오마커, [키워드] Accuracy adverse impact approach assessment Biochemistry Biomarkers clinical trial COVID-19 death Digital Digital genomic signature DNA DNA sequence energy event feature genomic Gibbs energy h-distance. Health Host humans hybridization machine machine learning machine learning model methodology microbe mitigate new strain oligonucleotide Other pandemic pathogen pathogenic Pathogenic relationship pathogenicity Pathogens/nonpathogens Perspective predict Quality reducing sensitivity Sensitivity and specificity Sickness specificity structural property [DOI] 10.1007/s00438-022-01951-w PMC 바로가기
Electrochemical Aptasensing of SARS-CoV-2 Based on Triangular Prism DNA Nanostructures and Dumbbell Hybridization Chain ReactionArticle Published on 2022-10-252022-11-15 Journal: Analytical Chemistry [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] amplified chain clinical samples detect development DNA Dumbbell Efficiency hybridization Infection linear molecular nanostructure platform Prism provide reaction robust S1 protein SARS-CoV-2 sequence target protein the SARS-CoV-2 triangular utility [DOI] 10.1021/acs.analchem.2c03401 PMC 바로가기
An electrochemical aptasensor with N protein binding aptamer-complementary oligonucleotide as probe for ultra-sensitive detection of COVID-19N 단백질 결합 앱타머-상보성 올리고뉴클레오티드를 COVID-19의 초고감도 검출을 위한 프로브로 사용하는 전기화학적 앱타센서Article Published on 2022-10-012022-09-11 Journal: Biosensors & bioelectronics [Category] 치료기술, 치료제, [키워드] affected applied aptamer binding blood sample Blood samples changes in complementary Complementary DNA Concentration conformational COVID-19 COVID-19 epidemic COVID-19 in patients DNA double-stranded Early detection effective Electrochemical aptasensor gold hybridization Incubation linear relationship log logarithm N protein N protein detection probe R 2 Rapid Rapid COVID-19 diagnosis Regenerable aptamer sensor. reported sensor solution target the N protein throat swab throat swabs vaccination volunteers was measured [DOI] 10.1016/j.bios.2022.114436 PMC 바로가기 [Article Type] Article
Synthesis of Potential Antiviral Agents for SARS-CoV-2 Using Molecular Hybridization ApproachArticle Published on 2022-09-122022-11-15 Journal: Molecules [Category] SARS, 치료제, [키워드] agent antiviral property approach computational studies conjugate Conjugates cytotoxicity healthcare hybridization indole investigated molecular Molecular modeling Potential quinoline rhodanine. SAR-CoV-2 SARS-CoV-2 small molecule synthesis virus [DOI] 10.3390/molecules27185923 PMC 바로가기
Clinical evaluation of the Diagnostic Analyzer for Selective Hybridization (DASH): A point-of-care PCR test for rapid detection of SARS-CoV-2 infectionDASH(Diagnostic Analyzer for Selective Hybridization) 임상 평가: SARS-CoV-2 감염의 신속한 검출을 위한 현장 진료 PCR 검사Article Published on 2022-06-162022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료기술, [키워드] analyzed Analyzer Antigen calculated Cepheid clinical clinical setting collected Concordance conducted correlated COVID-19 COVID-19 symptoms COVID-19 vaccine cross-sectional cross-sectional study DASH dose doses enrolled evaluated female gold gold standard hybridization information Laboratory median age mRNA nasal swab negative and positive Negative predictive value participant PCR PCR test performed POC point-of-care positive Positive predictive value Predictive Predictive value provided SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR sensitivity specificity speed Swab symptomatic symptoms of COVID-19 vaccination was tested without symptom [DOI] 10.1371/journal.pone.0270060 PMC 바로가기 [Article Type] Article
Reprogrammed tracrRNAs enable repurposing of RNAs as crRNAs and sequence-specific RNA biosensors재프로그래밍된 tracrRNA는 RNA를 crRNA 및 서열 특이적 RNA 바이오센서로 용도 변경 가능Article Published on 2022-04-112022-09-11 Journal: Nature Communications [Category] Coronavirus, COVID19(2023년), SARS, 치료기술, 치료제, [키워드] alarm can not Cas9 cellular CRISPR DNA facilitate functions Genes genomic gRNA guide RNA hybridization hybridized in vitro Interaction mRNAs Protein RNA SARS-CoV-2 RNA sequence Streptococcus pyogene Streptococcus pyogenes transcriptional activity [DOI] 10.1038/s41467-022-29604-x PMC 바로가기 [Article Type] Article
Electrochemiluminescent nanostructured DNA biosensor for SARS-CoV-2 detectionSARS-CoV-2 검출을 위한 전기화학발광 나노구조 DNA 바이오센서Article Published on 2022-04-012022-09-11 Journal: Talanta [Category] COVID19(2023년), SARS, 치료기술, [키워드] AuNMs biosensor carbon changes in Combination detect Detection limit DNA DNA biosensor DNA sequence ECL gold Gold nanoparticle hybridization mixture platform SARS-CoV-2 SARS-CoV-2 detection shown [DOI] 10.1016/j.talanta.2021.123203 PMC 바로가기 [Article Type] Article
Hybridization chain reaction circuit-based electrochemiluminescent biosensor for SARS-cov-2 RdRp gene assaySARS-cov-2 RdRp 유전자 분석을 위한 혼성화 연쇄 반응 회로 기반 전기화학발광 바이오센서Article Published on 2022-04-012022-09-11 Journal: Talanta [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] activated amplification applied Au-g-C(3)N(4) Base pairing Chain Reaction complementary complex decrease detect Detection limit DNA ECL gradually increased HCR hybridization Luminescence nucleic acids probe quantified RdRP RdRp gene SARS-CoV-2 nucleic acid SARS-CoV-2 RdRp SARS-CoV-2 RdRp gene signal target gene the SARS-CoV-2 this system Y-DNA. [DOI] 10.1016/j.talanta.2022.123207 PMC 바로가기 [Article Type] Article