Clean Grinding Technique: A Facile Synthesis and In Silico Antiviral Activity of Hydrazones, Pyrazoles, and Pyrazines Bearing Thiazole Moiety against SARS-CoV-2 Main Protease (M pro )Article Published on 2020-10-062022-10-30 Journal: Molecules [Category] COVID-19, MERS, SARS, [키워드] activity anti-viral activity average Bearing binding affinity Compound compounds condensation cyclo-condensation derivatives docking Evidence Grinding hydrazide hydrazone lifecycle M pro MDs moiety molecular docking Molecular dynamics simulation nelfinavir positive control SARS-CoV-2 SARS-CoV-2 Mpro SARS-CoV-2 main protease SARS-CoV-2 Mpro Structure synthesis virus was tested [DOI] 10.3390/molecules25194565 PMC 바로가기 [Article Type] Article
New hydrazine and hydrazide quinoxaline 1,4-di-N-oxide derivatives: In silico ADMET, antiplasmodial and antileishmanial activityArticle Published on 2017-04-152024-08-27 Journal: Bioorganic & Medicinal Chemistry Letters [Category] 말라리아, [키워드] hydrazide Hydrazine Leishmaniasis malaria Quinoxaline 1,4-di-N-oxide.