Anti-Biofilm Perspectives of Propolis against Staphylococcus epidermidis InfectionsArticle Published on 2024-06-292024-09-05 Journal: Biomolecules [Category] update2024, [키워드] Biofilms hydrophobicity Propolis Staphylococcus epidermidis zeta potential [DOI] 10.3390/biom14070779 PMC 바로가기 [Article Type] Article
Computational and comparative investigation of hydrophobic profile of spike protein of SARS-CoV-2 and SARS-CoVArticle Published on 2022-12-012023-07-10 Journal: Journal of biological physics [Category] COVID19(2023년), [키워드] aliphatic aromatic hydrophobicity SARS-CoV SARS-CoV-2 Spike protein [DOI] 10.1007/s10867-022-09615-x PMC 바로가기
Structural bioinformatics analysis of SARS-CoV-2 variants reveals higher hACE2 receptor binding affinity for Omicron B.1.1.529 spike RBD compared to wild type referenceSARS-CoV-2 변이체의 구조적 생물정보학 분석은 야생형 참조에 비해 Omicron B.1.1.529 스파이크 RBD에 대해 더 높은 hACE2 수용체 결합 친화력을 보여줍니다Article Published on 2022-08-252022-09-11 Journal: Scientific Reports [Category] SARS, 변종, 신약개발, [키워드] ACE2 binding affinity Alpha Amino acid amino acid substitution amino acid substitutions Analysis B.1.1.529 binding binding affinity Bioinformatics analysis calibrated characterized COVID-19 pandemic develop Effect hACE2 receptor Halo highest hydrophobicity infected with SARS-CoV-2 Interaction linear molecular dynamics Molecular dynamics simulation molecular dynamics simulations much higher new SARS-CoV-2 occurred omicron pandemic RBD Receptor binding domain receptor hACE2 reveal SARS-CoV-2 variant SARS-CoV-2 variants sequence Spread the RBD the SARS-CoV-2 variant variants VoC wild type [DOI] 10.1038/s41598-022-18507-y PMC 바로가기 [Article Type] Article
An Electrostatically-steered Conformational Selection Mechanism Promotes SARS-CoV-2 Spike Protein Variation정전기로 조종되는 구조적 선택 메커니즘은 SARS-CoV-2 스파이크 단백질 변이를 촉진합니다Article Published on 2022-07-152022-09-11 Journal: Journal of Molecular Biology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] ACE2 amino acids Analysis analyzed collected conformational conformational change conformational changes COVID-19 COVID-19 pandemic Critical Cross-species transmission epidemiological epidemiological surveillance Evolution fusion global public health global public health emergency HADDOCK heterogeneity host cell host cell receptor hydrophobicity identify immune evasion IMPROVE local interaction local interactions MOST outbreak promote Protein protein–protein interactions Recognition recorded reducing Region replacing risk S protein SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Selection sequence variation spike Substitution substitutions Surveillance the S protein trimer vaccination Vaccine development variant [DOI] 10.1016/j.jmb.2022.167637 PMC 바로가기 [Article Type] Article
Hydrophobic Residues at the Intracellular Domain of the M2 Protein Play an Important Role in Budding and Membrane Integrity of Influenza VirusArticle Published on 2022-05-112023-06-14 Journal: Journal of Virology [Category] Fulltext, 신종인플루엔자, [키워드] budding hydrophobicity LC3-interacting region matrix protein 2 membrane integrity. [DOI] 10.1128/jvi.00373-22 PMC 바로가기
An in-silico study of the mutation-associated effects on the spike protein of SARS-CoV-2, Omicron variantSARS-CoV-2, Omicron 변이체의 스파이크 단백질에 대한 돌연변이 관련 효과에 대한 in-silico 연구Article Published on 2022-04-212022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] accompanied Affect alkalinity all-atom molecular dynamics simulations B.1.1.529 change Combination concern COVID-19 pandemic Critical decrease delta variant demonstrated Effect electrostatic epitope Epitopes exhibit functional hACE2 Health higher affinity hydrogen Hydrogen bond hydrogen bonds hydrophobic hydrophobic interaction hydrophobic interactions hydrophobicity in silico Approach in-silico increase in Infection Interaction modulate molecular dynamics Molecular dynamics simulation mutated Mutation new infection omicron Omicron variant predict predicted Protein RBD receptor Receptor-binding domain residue residues SARS-CoV-2 spike glycoprotein Spike protein the RBD the receptor-binding domain the spike protein transmission rate variant Variation variations virus [DOI] 10.1371/journal.pone.0266844 PMC 바로가기 [Article Type] Article
Antiviral/antibacterial biodegradable cellulose nonwovens as environmentally friendly and bioprotective materials with potential to minimize microplastic pollution항바이러스/항균 생분해성 셀룰로오스 부직포는 미세플라스틱 오염을 최소화할 수 있는 환경 친화적이고 생물 보호적인 소재입니다.Article Published on 2022-02-152022-09-11 Journal: Journal of hazardous materials [Category] COVID19(2023년), SARS, 치료제, [키워드] activity Antibacterial Antiviral Aquatic ecosystems biodegradability Cellulose component coronavirus SARS-CoV-2 COVID-19 COVID-19 crisis crisis demonstrated dominant Environment equipment Face mask Face masks grafting guanidine hydrophobicity lack Mask Microstructure Neomycin neomycin sulfate Personal protective equipment Polymer Polypropylene PPE Protective raised reagent robust SARS-CoV-2 sulfate textiles Textiles. virucidal [DOI] 10.1016/j.jhazmat.2021.127391 PMC 바로가기 [Article Type] Article
Synthetic molecule libraries for nucleic acid delivery: Design parameters in cationic/ionizable lipids and polymersReview article Published on 2022-02-012022-10-05 Journal: Drug metabolism and pharmacokinetics [Category] 비임상, [키워드] biodegradability Cationic lipid Cationic polymer described develop drug Extracellular facilitate hydrophobicity in vitro in vivo Lipid Liver disease mechanism nanomedicine nanoparticle Nuclease nucleic acid Nucleic acid delivery Other parameter Polymer PROTECT recent Structure synthetic translated Treatment virus infection [DOI] 10.1016/j.dmpk.2021.100428 [Article Type] Review article
Prion-like Domains in Spike Protein of SARS-CoV-2 Differ across Its Variants and Enable Changes in Affinity to ACE2Article Published on 2022-01-252022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] ACE2 ACE2 receptor acute respiratory syndrome affinity Algorithm analyzed angiotensin-converting enzyme 2 B.1.1.529 caused change conformation conformational coronavirus coronavirus disease COVID-19 delta variant distribution domain functional higher affinity host cell receptor hydrophobicity in silico in viral omicron Omicron variant pandemic PrD prion prion-like domains Protein proteome RBD Receptor-binding domain residue SARS-CoV S protein SARS-CoV-2 sequence spike Spike protein the receptor-binding domain the SARS-CoV-2 the spike protein unique variant variants viral infections viruses α1 helix [DOI] 10.3390/microorganisms10020280 PMC 바로가기 [Article Type] Article
Hotspots for mutations in the SARS-CoV-2 spike glycoprotein: a correspondence analysisArticle Published on 2021-12-082022-10-04 Journal: Scientific Reports [Category] SARS, 신약개발, [키워드] acute respiratory syndrome Affect Analysis assumed binding circulation complex Computational biology and bioinformatics coronavirus correspondence dissect domain Efficacy Epitopes events Evolution furin cleavage site glycoprotein help Host receptors hydrophobicity Interaction Interpretation Mutation predicted Probability RBD RBD-ACE2 residue SARS-CoV-2 sequence spike structural biology Substitution Support target the RBD the SARS-CoV-2 Vaccine virus [DOI] 10.1038/s41598-021-01655-y PMC 바로가기 [Article Type] Article