Leprosy Reactions: Clinical Pharmacologist Perspective with Repurposed Medicationsarticle Published on 2023-12-312024-09-01 Journal: Infectious Disorders - Drug Targets [Category] 한센병, [키워드] Anti-leprosy drugs Biomarkers hypersensitivity reaction leprosy neuritis newer drugs plasma exchange [Article Type] article
Patients with previous immediate hypersensitivity reactions to polyethylene glycol can safely receive the BNT162b2 mRNA COVID-19 vaccineArticle Published on 2022-10-012022-11-15 Journal: Internal medicine journal [Category] 진단, [키워드] allergic anaphylaxis BNT162b2 mRNA Community COVID-19 COVID-19 vaccine doses eight Evidence first dose glycol hospital hypersensitivity hypersensitivity reaction Mild molecular weight New offered Patient Pfizer reaction receive receiving Record second dose thought Vaccine Vaccines [DOI] 10.1111/imj.15821 PMC 바로가기
Repeat subcutaneous administration of casirivimab and imdevimab in adults is well-tolerated and prevents the occurrence of COVID-19Randomized Controlled Trial Published on 2022-09-012022-10-04 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] administration adverse event antibody Casirivimab clinically conducted COVID-19 death defined demonstrated development dose doses double-blind Efficacy end point evaluate evaluated exploratory hypersensitivity reaction Imdevimab incidence of COVID-19 laboratory-confirmed monoclonal antibody occurred Occurrence occurrence of COVID-19 Odds ratio participant Placebo placebo-controlled trial Prevent proportion Randomized reaction reduction in Repeat reported risk reduction SARS-CoV-2 Seroconversion substantial risk Tolerability treatment period treatment-emergent adverse event uninfected volunteers [DOI] 10.1016/j.ijid.2022.06.045 PMC 바로가기 [Article Type] Randomized Controlled Trial
Monitoring Anti-PEG Antibodies Level upon Repeated Lipid Nanoparticle-Based COVID-19 Vaccine Administration반복적인 지질 나노입자 기반 COVID-19 백신 투여 시 항-PEG 항체 수준 모니터링Article Published on 2022-08-092022-09-12 Journal: International Journal of Molecular Sciences [Category] 진단, [키워드] adverse effects Analysis anti-PEG Ig anti-Spike Ig antibodies antibody booster Cohort COVID-19 COVID-19 vaccines dose Efficacy Evolution hypersensitivity reaction IgG IgM Immunity Level Lipid lipid-nanoparticle-mRNA (LNP-mRNA)-based vaccine. monitoring mRNA COVID-19 vaccines not affect Prevalence raised reducing repeated reported Result SARS-CoV-2 significant increase vaccinated individuals vaccination Vaccine [DOI] 10.3390/ijms23168838 PMC 바로가기 [Article Type] Article
Applying lessons learned from nanomedicines to understand rare hypersensitivity reactions to mRNA-based SARS-CoV-2 vaccines Reviews Published on 2022-04-072022-10-05 Journal: Nature nanotechnology [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 치료제, [키워드] adverse events Adverse reaction affected anaphylaxis Applying approach contribute Factor hypersensitivity hypersensitivity reaction immunization include individual knowledge manifestation mechanism mRNA mRNA vaccine mRNA vaccines mRNA-based SARS-CoV-2 vaccine nanomedicine nanomedicines predicted Predictive reaction recipient recommendation repeated Research risk Safe SARS-CoV-2 vaccines second dose Symptom the SARS-CoV-2 vaccination Vaccine viral variant viruses [DOI] 10.1038/s41565-022-01071-x [Article Type] Reviews
First Identified Case of Fatal Fulminant Necrotizing Eosinophilic Myocarditis Following the Initial Dose of the Pfizer-BioNTech mRNA COVID-19 Vaccine (BNT162b2, Comirnaty): an Extremely Rare Idiosyncratic Hypersensitivity ReactionPfizer-BioNTech mRNA COVID-19 백신(BNT162b2, Comirnaty)의 초기 투여 후 치명적인 전격성 괴사성 호산구성 심근염의 첫 번째 확인된 사례: 극히 드문 특발성 과민 반응Case Reports Published on 2022-04-012022-09-12 Journal: Journal of Clinical Immunology [Category] 진단, [키워드] adverse event adverse events Autopsy benefit BNT162b2 cause Complete Complication COVID-19 COVID-19 infection COVID-19 vaccines death described drug early diagnosis eosinophil Eosinophilic eosinophilic myocarditis facilitate first dose fulminant Hospital admission hypersensitivity hypersensitivity reaction Identified Intervention less male Mild mortality risk mRNA mRNA COVID-19 vaccines mRNA-based myocarditis Myopericarditis non-specific clinical feature observation occurred Other Pfizer-BioNTech reaction risk second dose Transient Treatment triggered vaccination Vaccine variety [DOI] 10.1007/s10875-021-01187-0 PMC 바로가기 [Article Type] Case Reports
Hypersensitivity reaction to hyaluronic acid dermal filler after COVID-19 vaccination: A series of cases in São Paulo, Brazil코로나19 예방접종 후 히알루론산 필러 과민반응: 브라질 상파울루에서 발생한 일련의 사례Case Reports Published on 2022-03-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 변종, [키워드] aesthetic procedure Brazil carried Case report COVID-19 COVID-19 vaccination COVID-19 vaccine delayed hypersensitivity dermal filler Hyaluronic acid hyaluronic acid. hypersensitivity hypersensitivity reaction omicron Patient professional vaccination variants [DOI] 10.1016/j.ijid.2022.01.024 PMC 바로가기 [Article Type] Case Reports
COVID-19 Vaccination Safety and Tolerability in Patients Allegedly at High Risk for Immediate Hypersensitivity ReactionsArticle Published on 2022-02-142022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] adenoviral vector allergy Analysis anaphylaxis Cell Cohort cohort of patient COVID-19 COVID-19 vaccination criteria disease doses female HAE Hereditary angioedema high risk hypersensitivity hypersensitivity reaction IHR Immediate incidence indication Mastocytosis Mild MOST mRNA-based COVID-19 vaccine mRNA-based vaccine occurred Occurrence Patient patient group patients pediatric performed protocol reaction reported retrospective risk Safe Safety SARS-CoV-2 Sex significantly Symptom Symptoms Tolerability vaccination vaccine dose Vaccines were assessed [DOI] 10.3390/vaccines10020286 PMC 바로가기 [Article Type] Article
Cutaneous and systemic hyperinflammation drives maculopapular drug exanthema in severely ill COVID-19 patients피부 및 전신 고인 염증은 심하게 아픈 Covid-19 환자에서 황반 약물 엑스 산마를 유도합니다.Article Published on 2022-02-012022-08-31 Journal: Allergy [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 치료기술, 치료제, [키워드] activated Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis analyzed CCL11 CD8 cellular chemokine chemokines Cluster Clustering coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 patient COVID-19 patients Cutaneous cytokine Cytokine storm Cytometry demonstrated Diagnosis drug rash drug-induced maculopapular exanthema. eosinophil eosinophilia Exanthema Features healthy controls hypersensitivity hypersensitivity reaction hypersensitivity reactions IFN-γ IL-4 IL-5 IL-6 inflammatory mediator Inflammatory mediators Macrophage MCP-3 MDR mediators nasopharyngeal Patient PCR performed positive promote proteomic rashe respiratory RNA sequencing robust SARS-CoV-2 serum severe acute respiratory syndrome Coronavirus severe COVID-19 patients skin biopsies skin biopsy systemic cytokine systemic hyperinflammation systemic symptom systemic symptoms T cell T cells TNF Transcriptome turn upregulation [DOI] 10.1111/all.14983 PMC 바로가기 [Article Type] Article
Delayed localized hypersensitivity reactions to COVID-19 mRNA vaccines: a 6-month retrospective studyCOVID-19 mRNA 백신에 대한 지연된 국소 과민 반응: 6개월 후향적 연구Article Published on 2022-01-012022-09-12 Journal: Clinical and experimental dermatology [Category] MERS, SARS, 진단, [키워드] case sery clinical COVID-19 Delayed hypersensitivity reaction hypersensitivity reactions individual mRNA mRNA COVID-19 vaccine reaction Retrospective study vaccination Vaccine Vaccines [DOI] 10.1111/ced.14856 PMC 바로가기 [Article Type] Article