An engineered 5-helix bundle derived from SARS-CoV-2 S2 pre-binds sarbecoviral spike at both serological- and endosomal-pH to inhibit virus entrySARS-CoV-2 S2에서 파생된 조작된 5나선 번들은 바이러스 진입을 억제하기 위해 혈청학적 pH와 엔도솜 pH 모두에서 사베코바이러스 스파이크를 사전 결합합니다.Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] [DOI] 10.1080/22221751.2022.2095308 PMC 바로가기 [Article Type] Article
Lucidenic acid A inhibits the binding of hACE2 receptor with spike protein to prevent SARS-CoV-2 invasionArticle Published on 2022-11-012022-11-15 Journal: Food and chemical toxicology : an international jo [Category] [DOI] 10.1016/j.fct.2022.113438 PMC 바로가기
Isolation of an escape-resistant SARS-CoV-2 neutralizing nanobody from a novel synthetic nanobody libraryArticle Published on 2022-09-162022-11-15 Journal: Frontiers in Immunology [Category] [DOI] 10.3389/fimmu.2022.965446 PMC 바로가기
COVID-19 symptom relationship to antibody response and ACE2 neutralization in recovered health systems employees before and after mRNA BNT162b2 COVID-19 vaccineArticle Published on 2022-09-092022-11-15 Journal: PLoS ONE [Category] [DOI] 10.1371/journal.pone.0273323 PMC 바로가기
Current status of antihistamine drugs repurposing for infectious diseasesReview article Published on 2022-09-012022-10-05 Journal: Medicine in Drug Discovery [Category] [DOI] 10.1016/j.medidd.2022.100140 [Article Type] Review article
Identification of a novel immune-inflammatory signature of COVID-19 infections, and evaluation of pharmacokinetics and therapeutic potential of RXn-02, a novel small-molecule derivative of quinoloneResearch article Published on 2022-09-012022-10-05 Journal: Computers in biology and medicine [Category] [DOI] 10.1016/j.compbiomed.2022.105814 [Article Type] Research article
A potent neutralizing antibody provides protection against SARS-CoV-2 Omicron and Delta variants via nasal deliveryArticle Published on 2022-08-302022-10-05 Journal: Signal Transduction and Targeted Therapy [Category] [DOI] 10.1038/s41392-022-01135-3 [Article Type] Article
Targeting the Receptor-Binding Motif of SARS-CoV-2 with D-Peptides Mimicking the ACE2 Binding Helix: Lessons for Inhibiting Omicron and Future Variants of ConcernACE2 결합 나선을 모방한 D-펩타이드로 SARS-CoV-2의 수용체 결합 모티프 표적화: 오미크론 및 우려되는 미래 변이를 억제하기 위한 교훈Article Published on 2022-08-082022-09-11 Journal: Journal of Chemical Information and Modeling [Category] [DOI] 10.1021/acs.jcim.2c00500 PMC 바로가기 [Article Type] Article
Potential medicinal plants involved in inhibiting 3CLpro activity: A practical alternate approach to combating COVID-19Review article Published on 2022-08-012022-10-05 Journal: Journal of integrative medicine [Category] [DOI] 10.1016/j.joim.2022.08.001 [Article Type] Review article
Two-pore channel blockade by phosphoinositide kinase inhibitors YM201636 and PI-103 determined by a histidine residue near pore-entrance Research Published on 2022-07-232022-10-05 Journal: Communications Biology [Category] [DOI] 10.1038/s42003-022-03701-5 [Article Type] Research