The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in miceArticle Published on 2023-01-172023-07-11 Journal: Cell Reports Medicine [Category] COVID19(2023년), [키워드] ADCC convalescent plasma COVID-19 Fc-effector IgA IgG IgM macrophages neutrophils. SARS-CoV-2 [DOI] 10.1016/j.xcrm.2022.100893 PMC 바로가기
Mucosal and Systemic Responses to Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination Determined by Severity of Primary InfectionArticle Published on 2022-12-212023-07-10 Journal: mSphere [Category] COVID19(2023년), [키워드] IgA IgG mucosal immunity SARS-CoV-2 systemic response vaccination. [DOI] 10.1128/msphere.00279-22 PMC 바로가기
Humoral immunity and B-cell memory in response to SARS-CoV-2 infection and vaccinationArticle Published on 2022-12-162023-07-10 Journal: Biochemical Society Transactions [Category] COVID19(2023년), [키워드] COVID-19 IgG memory B cell neutralizing antibody. omicron SARS-CoV-2 [DOI] 10.1042/BST20220415 PMC 바로가기
Duration of BA.5 neutralization in sera and nasal swabs from SARS-CoV-2 vaccinated individuals, with or without omicron breakthrough infectionArticle Published on 2022-12-092023-07-10 Journal: Med (New York, N.Y.) [Category] COVID19(2023년), [키워드] BA.5 breakthrough IgA IgG mucosal immunity neutralization omicron SARS-CoV-2 Translation to patients Vaccine variants. [DOI] 10.1016/j.medj.2022.09.010 PMC 바로가기
Repertoires of SARS-CoV-2 epitopes targeted by antibodies vary according to severity of COVID-19코로나19 중증도에 따라 항체 표적 SARS-CoV-2 에피토프 레퍼토리 달라Article Published on 2022-12-012022-09-11 Journal: Virulence [Category] COVID19(2023년), SARS, 진단, 치료법, [키워드] antibodies antibody Antigen association Asymptomatic asymptomatic individual asymptomatic infection betacoronavirus Betacoronavirus Community convalescent correlated COVID-19 COVID-19 severity develop diagnosed diagnostics disease severity domains Epitopes Evidence evidence of finding FIVE five groups HKU1 Hospitalization IgG IgGs Immunity immunogenic immunogenic peptide individual Infection less MERS-CoV nucleocapsid protein Nucleocapsid proteins OC43 participant pathogenic pathogenic mechanisms peptide peptide array peptides pilot study predicted Protein RBDs reaction Receptor binding domain Region repertoire SARS-CoV RBD SARS-CoV RBDs SARS-CoV-2 SARS-CoV-2 epitope SARS-CoV-2 epitopes seroconverted Seroprevalence seroprevalence. severity severity of COVID-19 symptomatic symptomatic COVID-19 symptomatic infection therapeutic therapeutic antibodies Vaccines Viral with COVID-19 without symptoms [DOI] 10.1080/21505594.2022.2073025 PMC 바로가기 [Article Type] Article
Immunodeficient patient experience of emergency switch from intravenous to rapid push subcutaneous immunoglobulin replacement therapy during coronavirus disease 2019 shieldingArticle Published on 2022-12-012022-11-15 Journal: Current opinion in allergy and clinical immunology [Category] 진단, [키워드] administration Anxiety assessment collected Concentration coronavirus disease COVID-19 greater high risk IgG IgG level immunodeficient patient Immunoglobulin immunoglobulin replacement therapy In-hospital Infection intravenous Intravenous immunoglobulin IVIG Laboratory Measures mitigate outcome Patient receiving recent reported risk severe coronavirus disease shielding subcutaneously Subjective transitioned [DOI] 10.1097/ACI.0000000000000864 PMC 바로가기
COVID-19 breakthrough infections and humoral immune response among BNT162b2 vaccinated healthcare workers in Malaysia말레이시아에서 BNT162b2 백신을 접종한 의료 종사자의 COVID-19 획기적인 감염 및 체액성 면역 반응Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] 95% CI affected age Anti-S1 Anti-spike antibody Antibody Response antibody titres association Asymptomatic Asymptomatic individuals blood sample Blood samples BNT162b2 booster vaccination breakthrough Breakthrough infection breakthrough infections collected COVID-19 COVID-19 infection delta variant detectable domain geometric mean geometric mean titre GMT HCWs healthcare healthcare worker Healthcare workers humoral humoral immune response Humoral immunity IgG IgG assay individual individuals Infection investigated Malaysia not different notable outcome Participants prospective cohort study Protein response significantly significantly higher Support symptomatic the antibody response vaccination Vaccine vaccine doses vaccine. waned was measured [DOI] 10.1080/22221751.2022.2065936 PMC 바로가기 [Article Type] Article
Ultrasensitive monitoring of SARS-CoV-2-specific antibody responses based on a digital approach reveals one week of IgG seroconversionArticle Published on 2022-12-012022-11-15 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] addition antibodies Antibody Response approach AUC collected COVID-19 COVID-19 patient diagnostic diagnostics Donor Extreme early-stage seroconversion faster flow cytometry healthy IgG IgG and IgM IgG/IgM antibodies IgM immunoassay immunoassays immunological inactivated nucleic acid nucleic acids other diseases pathogen-specific Patient peptide platform probe Protein RBD reveal Rhesus monkeys SARS-CoV-2 S2 sensitivity Seroconversion seroconversion time Simoa tested Ultrasensitive digital detection. vaccination virus wild-type [DOI] 10.1016/j.bios.2022.114710 PMC 바로가기
SARS-CoV-2 IgG seropositivity after the severe Omicron wave of COVID-19 in Hong KongArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] age Anti-RBD IgG antibody children consequence COVID-19 diagnosed group Health healthcare Hong Kong IgG incidence individual Infection lowest measure nucleoprotein Older omicron ORF8 Public Receptor binding Receptor binding domain reflect SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection seropositive serosurveillance. subclinical infection vaccination variant [DOI] 10.1080/22221751.2022.2106899 PMC 바로가기
The long term vaccine-induced anti-SARS-CoV-2 immune response is impaired in quantity and quality under TNFα blockadeArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Activation acute respiratory syndrome alteration analysed anti-SARS-CoV-2 anti-SARS-CoV-2 IgG anti-TNF-α appear Autoimmune Autoimmune diseases blockade bystander Cell changes in chronic inflammatory disease Cohort comparable Control coronavirus COVID-19 Decline drugs Effect Efficacy ELISA flow cytometry groups healthy humoral immune response IgG immune cell populations immune response immunoblot investigated less Live virus Necrosis Neutralization assay neutralize neutralizing antibody neutralizing capacity Older omicron Patient patients plasma Plasma cell recipient reduced response SARS-CoV-2 second vaccination significantly T cell subset titre TNF-α TNFα tumor necrosis factor inhibitors tumor necrosis factor-α vaccination vaccination. Vaccine variants of concern virus VoC was increased while [DOI] 10.1002/jmv.28063 PMC 바로가기