Evaluation of qualitative and semi-quantitative cut offs for rapid diagnostic lateral flow test in relation to serology for the detection of SARS-CoV-2 antibodies: findings of a prospective studyArticle Published on 2022-10-312022-11-15 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] 95% CI Accuracy acute respiratory syndrome Analysis antibodies antibody Antibody detection assessments Blood capillary blood chemiluminescent immunoassay CLIA coronavirus coronavirus disease COVID-19 COVID-19 disease cut off cut-off Diagnosis diagnosis of COVID-19 diagnostic Efficacy ELISA evaluate facilitate gold standard identify IgM and IgG immunochromatographic assay information intensity Italy Laboratory Lateral lateral flow lateral flow immunoassay Lateral flow test measure NAAT Non-invasive nucleic acid amplification Patient patients performed POC positive Prospective Study provided Quantitative Rapid Rapid diagnostic test RDT SARS-CoV-2 SARS-CoV-2 antibody semi-quantitative sensitivity serological test serology Severity of disease specificity symptom onset Test the timing venous whole sample [DOI] 10.1186/s12879-022-07786-5 PMC 바로가기
Anti-SARS-CoV-2 antibody immunoreactivity profiles during COVID-19 recurrenceArticle Published on 2022-10-242022-11-15 Journal: Revista da Sociedade Brasileira de Medicina Tropic [Category] COVID19(2023년), SARS, 진단, [키워드] antibody Clinical data correlated COVID-19 evaluate evaluated group healthcare worker IgG and IgM IgG antibody IgM and IgG immunoreactivity Mild symptom profile SARS-CoV-2 seroconverted serum antibody spike receptor-binding domain symptomatic Symptoms the SARS-CoV-2 were assessed were used [DOI] 10.1590/0037-8682-0106-2022 PMC 바로가기
Coinfection and cross-reaction of dengue and COVID-19: a case series analysisArticle Published on 2022-10-212022-11-15 Journal: Revista da Sociedade Brasileira de Medicina Tropic [Category] 진단, [키워드] Analysis case sery clinical criteria Clinical symptoms Coinfection common clinical symptoms cough COVID-19 COVID-19 transmission cross-reaction Dengue fever determine diagnosing Diagnosis diagnostic died False-positive Follow-up headache Hospital admission IgG IgM IgM and IgG immunochromatographic Infection intensive care Laboratory lymphopenia myalgia Patient patients positive prevalent rapid serological test reactive recruited required risk RT-PCR serological severe COVID-19 manifestations similarity tested with COVID-19 worsening [DOI] 10.1590/0037-8682-0243-2022 PMC 바로가기
Development of a high-sensitivity and short-duration fluorescence in situ hybridization method for viral mRNA detection in HEK 293T cellsArticle Published on 2022-10-042022-11-15 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] acute respiratory syndrome addition antibody Antigen applied approach Blood caused Cell Cell culture cells Concentration contagious coronavirus Coronavirus disease 2019 COVID-19 development Diagnosis disease DNA virus effective false-negative False-positive results faster Fluorescence in situ hybridization gold standard HEK 293T HEK 293T cell hepatitis A virus HPV Human immunodeficiency virus human papillomavirus IgM and IgG IMPROVE influenza viruses limitation MERS-CoV Middle East Monkeypox mRNA patients plasmids probe Protein public health reduced respiratory syndrome coronavirus RNA RNA virus RT-PCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 viral Sensitivity and specificity significantly spike Surveillance tissue Treatment virus was increased yielding [DOI] 10.3389/fcimb.2022.960938 PMC 바로가기
COVID-19 seroprevalence and clinical picture in Swedish pediatric oncology and hematology patients스웨덴 소아 종양 및 혈액학 환자의 COVID-19 혈청 유병률 및 임상 양상Article Published on 2022-10-012022-09-12 Journal: Pediatric blood & cancer [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome age analyzed anti-S1 IgM anti-SARS-CoV-2 antibodies antibody blood sample clinical clinical picture Cohort collected coronavirus coronavirus disease COVID-19 cumulative develop Diagnosis disease electronic medical records hematology IgG antibody IgM and IgG immunology Immunosuppressive treatment incidence of COVID-19 increased risk Increasing Infection investigated majority Mild MOST National nine oncology outpatients pandemic Patient patient cohort patients PCR test pediatric pediatrics polymerase chain questionnaire recruited recruitment reported SARS-CoV-2 SARS-COV-2 infection seropositive severe COVID-19 study period Swedish symptomatic Treatment underlying disease Uppsala University vaccination wild-type [DOI] 10.1002/pbc.29773 PMC 바로가기 [Article Type] Article
Pre-vaccination immune response to COVID-19 in a population in Northeast PortugalArticle Published on 2022-10-012022-11-15 Journal: Irish Journal of Medical Science [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome age Analysis antibody application Asymptomatic coronavirus COVID-19 diagnosed Diagnosis exhibited group highest IgG IgM IgM and IgG immune response Immunity immunization individuals initial Laboratory median value participant Participants Patient PCR PCR diagnosis peaked Portugal Protein reported responders RT-PCR SARS-CoV-2 Seronegativity seropositive significant decrease statistically significant study population Symptom symptomatic vaccination [DOI] 10.1007/s11845-021-02799-6 PMC 바로가기
Prevalence, incidence and longevity of antibodies against SARS-CoV-2 among primary healthcare providers in Belgium: a prospective cohort study with 12 months of follow-upArticle Published on 2022-09-192022-11-15 Journal: BMJ Open [Category] SARS, 변종, 진단, [키워드] 95% CI age antibody asked Belgium booster vaccination Care circulation cohort study Complete COVID-19 COVID-19 infection dominant eight eligible Epidemiology Follow-up general medicine (see internal medicine) Health Healthcare provider IgM and IgG incidence internal Longevity measure natural infection participant Participants participated Patient patients physically Prevalence primary care Prospective prospective cohort study provided questionnaire reached Receptor binding domain Registered SARS-CoV-2 SARS-CoV-2 antibody secondary outcome serological test supported vaccination variant virus women [DOI] 10.1136/bmjopen-2022-065897 PMC 바로가기
High Seroprevalence of SARS-CoV-2 in Mwanza, Northwestern Tanzania: A Population-Based SurveyArticle Published on 2022-09-162022-11-15 Journal: International Journal of Environmental Research an [Category] SARS, 진단, 치료기술, [키워드] African antibodies antibody blood sample cause Community conducted country COVID-19 cross-sectional survey Data analysis detect distribution enrolled Evidence Factors IgG IgG and IgM IgM and IgG interquartile range investigated loss of taste magnitude median age Mwanza occurred participant prevention protocol rapid test kit SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 IgM selected seropositive Seroprevalence survey Tanzania the SARS-CoV-2 the SARS-CoV-2 virus Transmission understanding was obtained were used [DOI] 10.3390/ijerph191811664 PMC 바로가기
Kinetics of humoral immune response over 17 months of COVID-19 pandemic in a large cohort of healthcare workers in Spain: the ProHEpiC-19 studyArticle Published on 2022-09-032022-11-15 Journal: BMC Infectious Diseases [Category] SARS, 진단, [키워드] antibodies Asymptomatic Barcelona clinical Clinical spectrum Cohort COVID-19 COVID-19 pandemic criteria Critical determine Diagnosis disease disease severity Effect exceptional Factor Gender Health care health care workers healthcare healthcare worker healthy heterogeneous humoral immune response Humoral immunity IgG IgG and IgM IgM IgM and IgG immune response infected with SARS-CoV-2 interactions Kinetics kinetics of antibody large cohort Ministry of Health nine non-linear mixed model Non-linear mixed models nucleocapsid participant patients with asymptomatic positive provide public health Regional remained SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection Seroprevalence Significant study period the SARS-CoV-2 virus threshold understanding vaccination [DOI] 10.1186/s12879-022-07696-6 PMC 바로가기
Evaluating the immunogenicity of gold nanoparticles conjugated RBD with Freund’s adjuvant as a potential vaccine against SARS-CoV-2Article Published on 2022-09-012022-11-15 Journal: Microbial pathogenesis [Category] COVID19(2023년), SARS, 진단, [키워드] adjuvant Antigen assays BALB/c mice boost candidate candidate vaccine cell-mediated immune response cell-mediated response cloned COVID-19 COVID-19 pandemic COVID-19 vaccine cytokine E. coli ENhance evaluated Evaluating examined expressed Freund's adjuvant global pandemic gold Gold nanoparticle Gold nanoparticles Health Host humoral Humoral immunity Humoral response IFN-γ IgG IgM IgM and IgG immune immune response immune system Immunogenic proteins Incomplete injected interval long-term immune response marker material Nano-vaccines outcome pandemic purified RBD RBD antigen RBD protein repeated SARS-CoV-2 significantly higher stimulate structural protein the RBD protein treatment group Vaccine while [DOI] 10.1016/j.micpath.2022.105687 PMC 바로가기