Identification of 5-(3-(methylsulfonyl)phenyl)-3-(4-(methylsulfonyl)phenyl)-3H-imidazo[4,5-b]pyridine as novel orally bioavailable and metabolically stable antimalarial compound for further explorationarticle Published on 2023-03-312024-09-01 Journal: Chemical Biology & Drug Design [Category] 말라리아, [키워드] ADME-PK antimalarial docking Imidazopyridine PI4 kinase synthesis [Article Type] article
Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty강력한 이환형 말라리아 cGMP 의존성 단백질 키나제 억제제: 세포 효능, 선택성 및 구조적 참신성의 개선을 결합하는 접근법Article Published on 2019-10-012024-08-26 Journal: Bioorganic & Medicinal Chemistry Letters [Category] 말라리아, [키워드] cGMP Imidazopyridine malaria Plasmodium falciparum Protein kinase G SAR [DOI] 10.1016/j.bmcl.2019.08.014 PMC 바로가기 [Article Type] Article