Deciphering the role of alternative splicing in neoplastic diseases for immune-oncological therapiesImmunology Review Published on 2024-04-262024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] alternative splicing Antibody therapy CTLA-4 HLA-G Immune checkpoints PD-1 PD-L1 [DOI] 10.3389/fimmu.2024.1386993 PMC 바로가기 [Article Type] Immunology Review
Mycobacterium tuberculosis : immune response, biomarkers, and therapeutic interventionReviews Published on 2024-01-062024-09-05 Journal: MedComm [Category] update2024, [키워드] Biomarkers diagnostic methods Immune checkpoints immune response Mycobacterium tuberculosis (Mtb) therapeutic vaccines Tuberculosis (TB) [DOI] 10.1002/mco2.419 PMC 바로가기 [Article Type] Reviews
Sex Differences in Genomic Features of Hepatitis B-Associated Hepatocellular Carcinoma With Distinct Antitumor ImmunityArticle Published on 2023-01-012023-06-11 Journal: Cellular and molecular gastroenterology and hepato [Category] B형 간염, [키워드] aflatoxin DNA double-strand break HBV Immune checkpoints Sex hormones [DOI] 10.1016/j.jcmgh.2022.10.009 PMC 바로가기
Viral load is associated with mitochondrial dysfunction and altered monocyte phenotype in acute severe SARS-CoV-2 infection바이러스 부하는 급성 중증 SARS-CoV-2 감염에서 미토콘드리아 기능 장애 및 변경된 단핵구 표현형과 관련이 있습니다Article Published on 2022-07-012022-09-11 Journal: International immunopharmacology [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, [키워드] CD14 CD16 CD39 Cell cell surface classical monocyte classical monocytes Clinical outcome COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity determined by evaluated exhibited expression Frequency GM-CSF healthy control healthy controls high viral load HLA-DR Hospital admission IFN-α Immune checkpoints induce Infection initial innate immune innate immune response less membrane Mitochondria mitochondrial mitochondrial dysfunction Mitochondrial function monocyte Monocyte activation Monocytes oxygen pathological mechanism patients PD-1 phenotype reactive oxygen species reactive oxygen specy SARS-CoV-2 SARS-CoV-2 viral load severe COVID-19 severe COVID-19 patient severe COVID-19 patients severe SARS-CoV-2 severity the cell the median These data Viral viral burden Viral load with COVID-19 [DOI] 10.1016/j.intimp.2022.108697 PMC 바로가기 [Article Type] Article
Deciphering the Plasmodium falciparum malaria-specific CD4+ T-cell response: ex vivo detection of high frequencies of PD-1+TIGIT+ EXP1-specific CD4+ T cells using a novel HLA-DR11-restricted MHC class II tetramerArticle Published on 2022-04-042024-08-28 Journal: Clinical and Experimental Immunology [Category] 말라리아, [키워드] CD4+ T cells host–pathogen interactions Immune checkpoints inhibitory/activating receptors parasitic-protozoan.
Advances in CAR-T Cell Genetic Engineering Strategies to Overcome Hurdles in Solid Tumors TreatmentReview Published on 2022-02-082023-08-30 Journal: Frontiers in Immunology [Category] E형 간염, [키워드] Angiogenesis CAR-T cell immunotherapy chemokines Immune checkpoints solid tumor Tumor Homing tumor microenvironment Tumor stroma [DOI] 10.3389/fimmu.2022.830292 PMC 바로가기 [Article Type] Review
Plasmodium infection inhibits triple negative 4T1 breast cancer potentially through induction of CD8+ T cell-mediated antitumor responses in micearticle Published on 2021-06-302024-09-01 Journal: Biomedicine & Pharmacotherapy [Category] 말라리아, [키워드] CD8(+) T cells granzyme B Immune checkpoints Plasmodium infection Triple negative breast cancer [Article Type] article
Emerging Immunotherapies against Novel Molecular Targets in Breast CancerReview Published on 2021-02-282022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, [키워드] administration antibody Antigen approach bispecific antibodies Breast Breast cancer Cancer CAR CAR-T Cell chimeric clinician COVID-19 vaccine expression profiles form generate highlight Immune checkpoints Immunotherapy improvement in vitro in vivo marker molecular target mRNA vaccine novel precision therapy receptor Research target therapeutic therapy TNBC Treatment triple-negative breast cancer tumor marker tumor specific/associated antigens [DOI] 10.3390/ijms22052433 PMC 바로가기 [Article Type] Review
Anti-Tumorigenic Activities of IL-33: A Mechanistic InsightArticle Published on 2020-11-302023-08-30 Journal: Frontiers in Immunology [Category] E형 간염, [키워드] basophils CD8 T cells eosinophils IL-33 ILC2 Immune checkpoints tumor immunity tumor microenvironment [DOI] 10.3389/fimmu.2020.571593 PMC 바로가기
CTLA-4 antibody ipilimumab negatively affects CD4 + T-cell responses in vitroCTLA-4 항체 이필리무맙은 시험관 내에서 CD4 + T 세포 반응에 부정적인 영향을 미칩니다Original Article Published on 2019-07-222024-07-30 Journal: Cancer Immunology, Immunotherapy [Category] 파상풍, [키워드] Coinhibitory pathways CTLA-4 Immune checkpoints Ipilimumab tetanus toxoid [DOI] 10.1007/s00262-019-02369-x PMC 바로가기 [Article Type] Original Article