Evaluation of novel Epstein-Barr virus-derived antigen formulations for monitoring virus-specific T cells in pediatric patients with infectious mononucleosisResearch Published on 2024-06-142024-09-05 Journal: Virology Journal [Category] update2024, [키워드] Epstein-Barr virus Immune monitoring infectious mononucleosis Pediatric patients T-cell Response [DOI] 10.1186/s12985-024-02411-0 PMC 바로가기 [Article Type] Research
Development and application of EpitopeScan, a Python3 toolset for mutation tracking in SARS-CoV-2 immunogenic epitopesImmunology Technology and Code Published on 2024-05-222024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] epitope Immune monitoring mutation tracking rheumatoid arthritis SARS-CoV-2 Software Vaccine design [DOI] 10.3389/fimmu.2024.1356314 PMC 바로가기 [Article Type] Immunology Technology and Code
Dynamics of torque teno virus load in kidney transplant recipients with indication biopsy and therapeutic modifications of immunosuppressionMedicine Original Research Published on 2024-01-242024-09-05 Journal: Frontiers in Medicine [Category] update2024, [키워드] Immune monitoring Immunosuppression Kidney transplantation precision medicine torque teno virus [DOI] 10.3389/fmed.2024.1337367 PMC 바로가기 [Article Type] Medicine Original Research
Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapyResearch Article Published on 2021-08-052022-10-31 Journal: eLife [Category] COVID-19, MERS, SARS, [키워드] Algorithm Analysis Cancer therapy CD4+ cell CD4+ T cell Cell cells changes in Chemotherapy clinical response comparable Complete COVID-19 COVID-19 patient Cytometry Disease progression emerging disease example homogeneous hotspot Human identify immune Immune cell immune changes Immune monitoring immune system immunology individual donor Infection inhibitor knowledge leukemia machine learning magnitude Melanoma MHCII Other Patient phenotype Post-infection provided reagent repeated reveal rhinovirus SARS-CoV-2 infections Single Cell subset Systems biology therapy trajectory virus virus-specific T cell [DOI] 10.7554/eLife.64653 PMC 바로가기 [Article Type] Research Article
Novel ways to monitor immunosuppression in pediatric kidney transplant recipients—underlying concepts and emerging dataArticle Published on 2021-07-262023-08-30 Journal: Molecular and Cellular Pediatrics [Category] E형 간염, [키워드] Biomarkers Immune monitoring Immunosuppression Kidney transplantation pediatric transplantation viral infections virus-specific T cells [DOI] 10.1186/s40348-021-00118-8 PMC 바로가기
Affinity Tag Coating Enables Reliable Detection of Antigen-Specific B Cells in Immunospot AssaysArticle Published on 2021-07-212022-10-31 Journal: Cells [Category] COVID-19, SARS, [키워드] affinity affinity tag antibody antibody-secreting cell Antigen antigen coating antigen-specific antibody antigen-specific B cell antigens approach ASC assessment B-cell coating Cohort COVID-19 vaccinations detection Donor EBV Efficiency effort engage facilitate FluoroSpot functional HCMV hexahistidine Humoral immunity Hypothesis immune Immune monitoring immune protection ImmunoSpot infectious agent Influenza information membrane memory B cell memory B-cell non-specific plasmablast platform Prevent protein concentration provide Re-infection Receptor binding domain Recombinant protein reduction in required response SARS-CoV-2 SARS-COV-2 infection secondary antibody sensitivity serum significantly single-cell spike Streamline Tag tested these cell Viral antigen [DOI] 10.3390/cells10081843 PMC 바로가기 [Article Type] Article
Highly Sensitive Flow Cytometry Allows Monitoring of Changes in Circulating Immune Cells in Blood After Tdap Booster Vaccination고감도 유세포 분석을 통해 Tdap 추가 백신 접종 후 혈액 내 순환 면역 세포의 변화를 모니터링할 수 있습니다.Original Research Published on 2021-06-102024-07-28 Journal: Frontiers in immunology [Category] 백일해, 파상풍, [키워드] correlation networks flow cytometry Immune monitoring pertussis vaccine Plasma cells [DOI] 10.3389/fimmu.2021.666953 PMC 바로가기 [Article Type] Original Research
Deconvoluting the T Cell Response to SARS-CoV-2: Specificity Versus Chance and Cognate Cross-ReactivitySARS-CoV-2에 대한 T 세포 반응의 해체: 특이성 대 우연 및 동족 교차 반응성Immunology Published on 2021-05-282022-09-11 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 치료기술, [키워드] Antibody Response Antigen antigens Biomarker chance characteristic clinically Cognate Cold common common cold common cold Coronaviruses coronavirus Course COVID-19 cross-reactive cross-reactivity ELISPOT exposure to False negative Human Immune monitoring immune protection Immunological memory ImmunoSpot individual individuals induce infected individual infected individuals infected with SARS-CoV-2 majority mega peptide pools Mild MOST negative control negative controls peptide peptide pool peptide pools provided respond response SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-COV-2 infection serum antibodies serum antibody specific serum T cell T cell affinity T cell memory T cell response T cells Viral viral infections virus [DOI] 10.3389/fimmu.2021.635942 PMC 바로가기 [Article Type] Immunology
Highlights of the 33rd annual scientific meeting of the Association of Medical Laboratory Immunologists (AMLI)Review Published on 2021-05-012024-09-02 Journal: Journal of Immunological Methods [Category] 대상포진, [키워드] antinuclear antibodies COVID-19 histocompatibility Immune monitoring immunodeficiency Immunotherapy [DOI] 10.1016/j.jim.2021.112994 PMC 바로가기 [Article Type] Review
Immune reconstitution and clinical recovery following anti-CD28 antibody (TGN1412)-induced cytokine storm항-CD28 항체(TGN1412) 유발 사이토카인 폭풍 후 면역 재구성 및 임상 회복Clinical Trial Published on 2021-04-012022-08-31 Journal: Cancer immunology, immunotherapy : CII [Category] MERS, SARS, 바이오마커, 임상, 진단, [키워드] adverse event adverse events antibody asymptomatic patients autoantibody Cancer immunotherapy CD28 CD4 CD8 cells clinical recovery clinical trial cognitive Cognitive deficits Concentration consequence COVID-19 cytokine Cytokine dysregulation cytokine release Cytokine release syndrome Cytokine storm Cytokines Day declined defined dendritic cell dendritic cells Depression described diagnosed dry gangrene dysregulation elevated Follow-up Gastrointestinal healthy volunteer IgE immune immune dysregulation Immune monitoring Immune-related adverse events (irAEs) immunopathology Immunotherapy infections initial irAEs irritability memory Mild-to-moderate mucosal naïve neutropenia observation one patient over Patient problem problems pruritus Psychological raynaud s phenomenon required serum cytokine serum cytokines subset suffered Symptom systemic symptoms T-cell T-cells T-regulatory cell T-regulatory cells targets TGN1412. Treatment undetectable [DOI] 10.1007/s00262-020-02725-2 PMC 바로가기 [Article Type] Clinical Trial