BNT162b2 coronavirus disease-2019 vaccination accelerated rheumatoid arthritis disease activity in chronic eosinophilic pneumonia: A case reportArticle Published on 2022-09-302022-11-15 Journal: Medicine [Category] 진단, [키워드] accelerated adverse events Affect Anti-inflammatory antibody BNT162b2 Case report Cell coronavirus COVID-19 COVID-19 vaccination COVID-19 vaccine diagnosed Diagnosis Disease activity eosinophil Eosinophilic had no immune reactions Immunological response Inflammation initial joint laboratory examination peptide Pneumonia pulse reaction receiving reflected respiratory symptom response rheumatoid arthritis steroid treatment suggested Symptom Symptoms T cell T helper therapy vaccination worsened [DOI] 10.1097/MD.0000000000030806 PMC 바로가기
Omicron variant receptor-binding domain phylogenetics and molecular dynamics오미크론 변이체 수용체 결합 도메인 계통발생학 및 분자 역학Article Published on 2022-07-012022-09-11 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 변종, [키워드] addition Alpha alpha and delta variants Amino acid analyses angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Angiotensin-converting enzyme 2 receptor anticipated antigenic antigenic epitope antigenic epitopes antigenic site arithmetic mean Beta binding changes in Clustering conformation conserved COVID-19 Delta deviation domain epitope Epitopes evolutionary relationships expected FIVE fluctuation Gamma greater immune reactions investigated MD simulations molecular molecular dynamics Mutation mutations omicron Omicron variant other variants Phylogenetic Phylogenetic relationship phylogenetics predicted RBD RBD binding RBD mutation RBD of SARS-CoV-2 receptor Receptor-binding domain residue residues Root-mean-square deviation SARS-CoV-2 SARS-CoV-2 RBD SARS-CoV-2 variant SARS-CoV-2 variants sequence significantly suggested surface area tested the receptor-binding domain the SARS-CoV-2 variant variants [DOI] 10.1016/j.compbiomed.2022.105633 PMC 바로가기 [Article Type] Article
Autochthonous leprosy in Europe: a case report and literature reviewarticle Published on 2021-09-302024-09-01 Journal: International journal of infectious diseases : IJID : official publication [Category] 한센병, [키워드] Autochthonous leprosy Europe Hansen's disease immune reactions [Article Type] article
Putative Role of Vitamin D for COVID-19 VaccinationCOVID-19 예방 접종을 위한 비타민 D의 추정 역할Review Published on 2021-08-202022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 변종, 임상, [키워드] 2019 coronavirus disease ACE2 expression acute respiratory syndrome acute respiratory syndrome coronavirus adaptive Adaptive immunity airways Analysis angiotensin applied caused characterized Clinical use complementary complex component coronavirus coronavirus disease correlated COVID-19 COVID-19 vaccines Cytokines defend delayed response demonstrated develop DNA effective Effectiveness Efficacy effort elicited Evidence Extensive Factor global pandemic highly pathogenic IFN-III Immune cell infiltration immune dysfunction immune reactions immune signaling pathways Immunity inactivated incidence innate immune response Innate immunity innate response Interaction interferon interferons involved knowledge mechanism modulation molecular mechanism mRNA observational studies observational study pathophysiological progression Proinflammatory cytokine proinflammatory cytokines Protein subunit vaccines pulmonary disease RAS reduce Renin renin-angiotensin system respiratory role SARS-CoV-2 Serum level serum levels severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 patient severe COVID-19 patients severity severity of COVID-19 shown Significant Strategy subunit vaccines synthesis Treatment Vaccine vaccine efficacy Vaccines variant virus viruses Vitamin D Vitamin D supplementation [DOI] 10.3390/ijms22168988 PMC 바로가기 [Article Type] Review
COVID-19 in Children: Expressions of Type I/II/III Interferons, TRIM28, SETDB1, and Endogenous Retroviruses in Mild and Severe CasesArticle Published on 2021-07-132022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] Activation Adults Amplification assay children comparable Concentration contribute controls correlation COVID-19 COVID-19 patient COVID-19 patients cross-talk Decline deficiency disease endogenous Evolution Exogenous expression expression level Genes HERV HERVs human endogenous retrovirus human endogenous retroviruses IFN IFN-I IFN-III IFN-λ IFNs immune reactions immune response induce Infection Inflammatory information interferon involved Mild mild symptoms MIS-C moderate disease New coronavirus patients PCR Pediatric patients Peripheral blood positive correlation preserved Prognosis real time regulate reported retrovirus SARS-CoV-2 SARS-COV-2 infection SETDB1 Severe case severe disease stimulated subjects Symptom SYN2 syndrome Transcription transcriptional level TRIM28 turn Type type I uninfected upregulation viral infection [DOI] 10.3390/ijms22147481 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Causes Severe Epithelial Inflammation and Barrier DysfunctionVirus-Cell Interactions Published on 2021-02-262022-10-30 Journal: Journal of Virology [Category] COVID-19, [키워드] accompanied acute respiratory syndrome affected alveolar Asymptomatic barrier cause cell type chip model complex component composed conducted coronavirus Coronavirus disease-19 Course courses COVID-19 Culture cytokine damaged dependent on dissemination Effect endothelial Endothelial cell Endothelium epithelial epithelial cell epithelial/endothelial barrier experimental model experiments expression Factor Health care system homeostatic Host immune reactions in vitro experiments infected with SARS-CoV-2 Infection Inflammatory response Interaction interferon interferons Mild molecular mononuclear cells overcome Prolonged infection promote Replication Research Respiratory system SARS-CoV-2 severe COVID-19 severe COVID-19 disease Symptom systemic symptoms the disease Thromboembolic event variety viral infection Viral load viral particle viral pathogen viral spread Viremia virus virus replication [DOI] 10.1128/JVI.00110-21 PMC 바로가기 [Article Type] Virus-Cell Interactions
Case Report: Posterior Reversible Leukoencephalopathy Syndrome (PRES) as a Biologically Predictable Neurological Association in Severe COVID-19. First Reported Case From Australia and Review of Internationally Published CasesNeurology Published on 2021-01-272022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] ACE2 receptors blood pressure Brain Case report change clinical status clinical suspicion clinically co-morbidities Confusion COVID-19 Cytokine storm delirium diagnosed diagnosed with COVID-19 downregulation Encephalopathy Endotheliitis exacerbated full recovery Headaches hypertension hypertensive immune reactions kidney leukoencephalopathy MRI neurological manifestation patients with COVID-19 Posterior posterior reversible encephalopathy syndrome (pres) problems Renin report reported reversed Reversible review SARS-CoV-2 supported syndrome therapy Variability vulnerable patient [DOI] 10.3389/fneur.2020.600544 PMC 바로가기 [Article Type] Neurology
Use of biologicals in allergic and type-2 inflammatory diseases during the current COVID-19 pandemic Position paper of Ärzteverband Deutscher Allergologen (AeDA) , Deutsche Gesellschaft für Allergologie und Klinische Immunologie (DGAKI) , Gesellschaft für Pädiatrische Allergologie und Umweltmedizin (GPA) , Österreichische Gesellschaft für Allergologie und Immunologie (ÖGAI) , Luxemburgische Gesellschaft für Allergologie und Immunologie (LGAI) , Österreichische Gesellschaft für Pneumologie (ÖGP) in co-operation with the German, Austrian, and Swiss ARIA groups , and the European Academy of Allergy and Clinical Immunology (EAACI)Research Article Published on 2020-09-072022-10-28 Journal: Allergologie Select [Category] COVID-19, [키워드] Academy Affect allergic allergic disease analyzed atopic atopic dermatitis benefit benralizumab bronchial asthma Care carried clinical collected complex Course courses COVID-19 COVID-19 pandemic Cytokine storm decrease develop disease disease course drastic Dupilumab early phase Effect European Evidence group immune reaction immune reactions immune response immunological increased risk Infection infection risk infection with SARS-CoV-2 inflammatory disease inhibit Interaction involved lack later phase maintain material mechanisms mepolizumab monoclonal antibodies nasal offer omalizumab pandemic Patient patients patients treated position positive potential risk provide question recommendation reslizumab risk Safe SARS-CoV-2 SARS-COV-2 infection selective severe COVID-19 Telemedicine the patient therapy These data Treatment [DOI] 10.5414/ALX02166E PMC 바로가기 [Article Type] Research Article
A contemporary review on pathogenesis and immunity of COVID-19 infectionOriginal Article Published on 2020-06-292023-07-01 Journal: Molecular biology reports [Category] SARS, [키워드] coronavirus COVID-19 cytopathic effects immune reactions viral accessory proteins viral receptors [DOI] 10.1007/s11033-020-05621-1 PMC 바로가기 [Article Type] Original Article